scholarly journals Come from away: Best practices in mini-sabbaticals for the development of young investigators: a White Paper by the SEQUIN (mini-Sabbatical Evaluation and QUality ImprovemeNt) Group

2019 ◽  
Vol 3 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Michael H. Pillinger ◽  
Stephenie C. Lemon ◽  
Martin S. Zand ◽  
P. Jeffrey Foster ◽  
Jeanne S. Merchant ◽  
...  
Keyword(s):  
Best Practice ◽  
Research Unit ◽  
White Paper ◽  
National Institutes Of Health ◽  
Regulatory Agencies ◽  
Limited Data ◽  
Non Profit ◽  
History Of ◽  
Training Institutions ◽  
And Training

AbstractMini-sabbaticals are formal short-term training and educational experiences away from an investigator’s home research unit. These may include rotations with other research units and externships at government research or regulatory agencies, industry and non-profit programs, and training and/or intensive educational programs. The National Institutes of Health have been encouraging training institutions to consider offering mini-sabbaticals, but given the newness of the concept, limited data are available to guide the implementation of mini-sabbatical programs. In this paper, we review the history of sabbaticals and mini-sabbaticals, report the results of surveys we performed to ascertain the use of mini-sabbaticals at Clinical and Translational Science Award hubs, and consider best practice recommendations for institutions seeking to establish formal mini-sabbatical programs.

scholarly journals Void spot assay: recommendations on the use of a simple micturition assay for mice

2018 ◽  
Vol 315 (5) ◽  
pp. F1422-F1429 ◽  
Author(s):  
Warren G. Hill ◽  
Mark L. Zeidel ◽  
Dale E. Bjorling ◽  
Chad M. Vezina
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Best Practice ◽  
Assessment Tool ◽  
National Institutes Of Health ◽  
Consensus Group ◽  
Lower Urinary Tract Function ◽  
Tract Function ◽  
History Of ◽  
Lower Urinary

Investigators have for decades used mouse voiding patterns as end points for studying behavioral biology. It is only recently that mouse voiding patterns were adopted for study of lower urinary tract physiology. The spontaneous void spot assay (VSA), a popular micturition assessment tool, involves placing a mouse in an enclosure lined by filter paper and quantifying the resulting urine spot pattern. The VSA has advantages of being inexpensive and noninvasive, but some investigators challenge its ability to distinguish lower urinary tract function from behavioral voiding. A consensus group of investigators who regularly use the VSA was established by the National Institutes of Health in 2015 to address the strengths and weaknesses of the assay, determine whether it can be standardized across laboratories, and determine whether it can be used as a surrogate for evaluating urinary function. Here we leverage experience from the consensus group to review the history of the VSA and its uses, summarize experiments to optimize assay design for urinary physiology assessment, and make best practice recommendations for performing the assay and analyzing its results.

scholarly journals INFOTERM – Information Disseminating Centre for Terminology

2014 ◽  
Vol 22 (2) ◽  
pp. 112-120
Author(s):  
Albina AUKSORIŪTĖ
Keyword(s):  
Knowledge Transfer ◽  
United Nations ◽  
Knowledge Society ◽  
Non Profit ◽  
Information Centre ◽  
United Nations Educational ◽  
Cultural Organization ◽  
The World ◽  
History Of ◽  
And Training

International Information Centre for Terminology (INFOTERM) was founded in 1971 by contract with the United Nations Educational, Scientific and Cultural Organization (UNESCO) and the Austrian Standards Institute (ASI). In 1996, INFOTERM was reorganized and established as an independent non-profit organization. INFOTERM promotes and supports the cooperation of existing and the establishment of new terminology centres and networks with the general aim to improve domain communication, knowledge transfer and provision of content with view to facilitating the participation of all in the global multilingual knowledge society. The article presents not only a history of the foundation of INFOTERM, the tasks and activities of INFOTERM and its members, which are international, regional or national terminology institutions, organizations and networks, as well as specialized public or semi-public or other non-profit institutions engaged in terminological activities, but also analyses “Guidelines for terminology policies”, preparied by INFOTERM, and cooperation between INFOTERM and the Institute of the Lithuanian Language.In conclusion, the experience and sharing expertise of INFOTERM regarding harmonized methods and guidelines for terminology management and policies, the management of terminology centres, terminology standardization, the use of terminological data, methods and tools in all applications etc are very important for all countries and language communities especially for countries and language communities with less mature terminologies. The Institute of the Lithuanian Language as a member of INFOTERM has a possibility to get information on terminology research and training, terminology publications, terminological events and activities all over the world.

Studying Effective Educational Strategies in Reducing Extremist Phenomena in Quran and Holy Books

2021 ◽  
pp. 138-145
Author(s):  
Esmail Salem Khoei ◽  
Seyyed Taghi Kabiri ◽  
Mahboob Mahdavian
Keyword(s):  
Educational Strategies ◽  
Cultural Economic ◽  
Theoretical Support ◽  
The Social ◽  
Inclusive Approach ◽  
History Of ◽  
Training Institutions ◽  
Sociological Approaches ◽  
The Individual ◽  
And Training

Nowadays, the educational and training institutions' activities are adjusted based on moral and human principles. Inhibiting and ultimately eliminating the real extremist organizations is a vital need of society. Now it is clear to everyone that an effective and successful fight against these phenomena requires an inclusive approach and a multi-sectoral strategy that, over and above all, is related to a conscious understanding of the social, cultural, economic, and global conditions. Consequently, it is crucial to study the solutions and correct imparting policy-making in the field of extremist phenomena, which is a global problem and has been condemned in the divine religions. The bloodshed and killing phenomenon as a tool to attain goals that do not presently exist, has happened a lot in the history of different societies, thus one of the dimensions of cognition and thinking to eradicate it, is related to the mental and theoretical support of its supporter. The current research has been prepared and compiled in a descriptive-analytical method. Based on the research results, it can be indicated that paying attention to the cultural peace strategy, the importance of science, education, and culture, and scientific-educational development play an important role in preventing the spread of extremist phenomena. Hence, adopting sociological approaches and strategies to promote social capacities at the individual and organizational (social) level is suggested.

scholarly journals INGGRIS SEBAGAI SENTRAL KEUANGAN ISLAM DI BARAT

2016 ◽  
Vol 1 (1) ◽  
pp. 120-143
Author(s):  
Ahmad Irvani
Keyword(s):  
Insurance Markets ◽  
Islamic Banking ◽  
Future Prospects ◽  
Banking And Finance ◽  
Excess Liquidity ◽  
History Of ◽  
Training Institutions ◽  
Increasing Demand ◽  
The Uk ◽  
And Training

United Kingdom is a country that is predominantly by non-Muslim, but development of Islamic banking and finance is very good. This is evidenced by the operation of six full sharia bank and the sixteen banks that serve Islamic windows. Sukuk deals for investors is also growing as evidenced by the increasing demand on the London Stock Exchenge with a total of £51 billion. Likewise with takaful products, UK re/insurance markets that are transacting Islamic finance. As one of the largest insurance markets in the world, and the leading global centre for wholesale insurance and reinsurance, the UK has the potential to support the growth of takaful business in the coming years. The development of Islamic banking and finance did not escape from the multicultural population of the UK. From the research, UK residents both Muslims and non-Muslims showed 66% of respondents believe the Islamic financial system is suitable for western economic communities such as the UK. 65% of respondents understand the workings of Islamic banking differs from conventional banking workings. 60% of respondents agree Islamic banking relevant to all religions. 57% of respondents also knew of Islamic banking to give the profit, not the interest. This means that they responded positively to the products offered Islamic banking and finance. There are several factors that lead to Islamic banking and finance can be grown in the UK, there are: including the global expansion of Islamic financial, single banking and financial regulator, public policy and taxation, the establishment of the Islamic Bank of Britain, the excess liquidity in the Middle East, Islamic windows of regular banks, and the development of educational and training institutions in the UK. This paper will describe the history of Islamic banking and finance in the UK, its development, factors that support and the its future prospects for giving additional knowledge to the academics and practitioners.

scholarly journals Translating Psychedelic Therapies From Clinical Trials to Community Clinics: Building Bridges and Addressing Potential Challenges Ahead

2021 ◽  
Vol 12 ◽  
Author(s):  
Martin L. Williams ◽  
Diana Korevaar ◽  
Renee Harvey ◽  
Paul B. Fitzgerald ◽  
Paul Liknaitzky ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Best Practice ◽  
Early Stage ◽  
Mental Illnesses ◽  
Community Practice ◽  
Community Clinics ◽  
Access To Treatment ◽  
History Of ◽  
Support Of Research ◽  
And Training

Research exploring the potential of psychedelic-assisted therapies to treat a range of mental illnesses is flourishing, after the problematic sociopolitical history of psychedelics led to the shutdown of clinical research for almost 40 years. Encouraged by positive results, clinicians and patients are now hopeful that further interruptions to research will be avoided, so that the early promise of these therapies might be fulfilled. At this early stage of renewed interest, researchers are understandably focusing more on clinical trials to investigate safety and efficacy, than on longer-term goals such as progression to community practice. Looking to identify and avoid potential pitfalls on the path to community clinics, the authors, a group of Australian clinicians and researchers, met to discuss possible obstacles. Five broad categories of challenge were identified: 1) inherent risks; 2) poor clinical practice; 3) inadequate infrastructure; 4) problematic perceptions; and 5) divisive relationships and fractionation of the field. Our analysis led us to propose some strategies, including public sector support of research and training to establish best practice and optimize translation, and funding to address issues of equitable access to treatment. Above all, we believe that strategic planning and professional cohesion will be crucial for success. Accordingly, our key recommendation is the establishment of a multidisciplinary advisory body, broadly endorsed and representing all major stakeholders, to guide policy and implementation of psychedelic-assisted therapies in Australia. Although these challenges and strategies are framed within the Australian context, we sense that they may generalize to other parts of the world. Wherever they apply, we believe that anticipation of potential difficulties, and creative responses to address them, will be important to avoid roadblocks in the future and keep the “psychedelic renaissance” on track.

Predictive value of the ankle brachial index in patients with acute ischemic stroke

VASA ◽  
2014 ◽  
Vol 43 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Konstantinos Tziomalos ◽  
Vasilios Giampatzis ◽  
Stella Bouziana ◽  
Athinodoros Pavlidis ◽  
Marianna Spanou ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Hospital Mortality ◽  
Acute Ischemic Stroke ◽  
Ankle Brachial Index ◽  
Arterial Disease ◽  
National Institutes Of Health ◽  
Limited Data ◽  
Severe Stroke ◽  
Hospital Outcome ◽  
Peripheral Arterial

Background: Peripheral arterial disease (PAD) is frequently present in patients with acute ischemic stroke. However, there are limited data regarding the association between ankle brachial index (ABI) ≤ 0.90 (which is diagnostic of PAD) or > 1.40 (suggesting calcified arteries) and the severity of stroke and in-hospital outcome in this population. We aimed to evaluate these associations in patients with acute ischemic stroke. Patients and methods: We prospectively studied 342 consecutive patients admitted for acute ischemic stroke (37.4 % males, mean age 78.8 ± 6.4 years). The severity of stroke was assessed with the National Institutes of Health Stroke Scale (NIHSS)and the modified Rankin scale (mRS) at admission. The outcome was assessed with the mRS and dependency (mRS 2 - 5) at discharge and in-hospital mortality. Results: An ABI ≤ 0.90 was present in 24.6 % of the patients whereas 68.1 % had ABI 0.91 - 1.40 and 7.3 % had ABI > 1.40. At admission, the NIHSS score did not differ between the 3 groups (10.4 ± 10.6, 8.3 ± 9.3 and 9.3 ± 9.4, respectively). The mRS score was also comparable in the 3 groups (3.6 ± 1.7, 3.1 ± 1.8 and 3.5 ± 2.3, respectively). At discharge, the mRS score did not differ between the 3 groups (2.9 ± 2.2, 2.3 ± 2.1 and 2.7 ± 2.5, respectively) and dependency rates were also comparable (59.5, 47.6 and 53.3 %, respectively). In-hospital mortality was almost two-times higher in patients with ABI ≤ 0.90 than in patients with ABI 0.91 - 1.40 or > 1.40 but this difference was not significant (10.9, 6.6 and 6.3 %, respectively). Conclusions: An ABI ≤ 0.90 or > 1.40 does not appear to be associated with more severe stroke or worse in-hospital outcome in patients with acute ischemic stroke.

scholarly journals The relevance of public policies for the sustainability of community media: Lessons from Argentina

2019 ◽  
Vol 4 (2) ◽  
pp. 74-90
Author(s):  
Mara Soledad Segura ◽  
Alejandro Linares ◽  
Agustn Espada ◽  
Vernica Longo ◽  
Ana Laura Hidalgo ◽  
...  
Keyword(s):  
Latin American ◽  
Public Policies ◽  
The State ◽  
Audiovisual Communication ◽  
Community Media ◽  
Communication Services ◽  
Non Profit ◽  
Promotion Policies ◽  
History Of ◽  
Extreme Media

Since 2004 and for the first time in the history of broadcasting in the region, a dozen Latin American countries have acknowledged community radio and television stations as legal providers of audiovisual communication services. In Argentina, a law passed in 2009 not only awarded legal recognition to the sector, it also provided a promotion mechanism for community media. In this respect, it was one of the most ambitious ones in the region. The driving question is: How relevant are public policies for the sustainability of community media in Argentina? The argument is: even though the sector of community media has developed and persisted for decades in illegal conditions imposed by the state, the legalization and promotion policies carried out by the state from the perspective of human rights in a context of extreme media ownership concentration have been critical to the growth and sustainability of non-profit media.

scholarly journals Low Nucleotide Diversity in Chimpanzees and Bonobos

Genetics ◽  
2003 ◽  
Vol 164 (4) ◽  
pp. 1511-1518 ◽  
Author(s):  
Ning Yu ◽  
Michael I Jensen-Seaman ◽  
Leona Chemnick ◽  
Judith R Kidd ◽  
Amos S Deinard ◽  
...  
Keyword(s):  
Nucleotide Diversity ◽  
Nuclear Dna ◽  
Demographic History ◽  
Nuclear Genome ◽  
Limited Data ◽  
Effective Population ◽  
East Central ◽  
Dna Diversity ◽  
History Of ◽  
Mtdna Diversity

Abstract Comparison of the levels of nucleotide diversity in humans and apes may provide much insight into the mechanisms of maintenance of DNA polymorphism and the demographic history of these organisms. In the past, abundant mitochondrial DNA (mtDNA) polymorphism data indicated that nucleotide diversity (π) is more than threefold higher in chimpanzees than in humans. Furthermore, it has recently been claimed, on the basis of limited data, that this is also true for nuclear DNA. In this study we sequenced 50 noncoding, nonrepetitive DNA segments randomly chosen from the nuclear genome in 9 bonobos and 17 chimpanzees. Surprisingly, the π value for bonobos is only 0.078%, even somewhat lower than that (0.088%) for humans for the same 50 segments. The π values are 0.092, 0.130, and 0.082% for East, Central, and West African chimpanzees, respectively, and 0.132% for all chimpanzees. These values are similar to or at most only 1.5 times higher than that for humans. The much larger difference in mtDNA diversity than in nuclear DNA diversity between humans and chimpanzees is puzzling. We speculate that it is due mainly to a reduction in effective population size (Ne) in the human lineage after the human-chimpanzee divergence, because a reduction in Ne has a stronger effect on mtDNA diversity than on nuclear DNA diversity.

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