scholarly journals P.104 Glioblastomas located in the right hemisphere are associated with worse quality of life

Author(s):  
C Iorio-Morin ◽  
P Goffaux ◽  
M Descoteau ◽  
K Whittingstall ◽  
D Fortin

Background: Because glioblastoma is currently incurable, the goal of therapy is the optimization of the patient’s quality of life (QOL). Tumor location is critical in screening surgical candidates, yet the impact of tumor location on QOL has never been demonstrated. By using a novel computer-driven algorithm, we set out to investigate the impact of tumor location on QOL. Methods: The tumors of fourty consecutive glioblastoma patients were segmented and the Euclidian distance between 90 brain regions and each tumor’s margin was calculated and correlated to the patients’ self-reported QOL as measured by the SNAS questionnaire. Results: QOL was statistically associated with proximity to three areas: the right para-hypocampal gyrus, the right posterior cingulate cortex and the right postcentral gyrus. We postulate that the adverse relation between proximity to these areas and QOL results from disruption in large-scale networks involved in high-order functions such as visuospatial memory. While harder to detect with a bedside clinical examination, such deficits are likely more impactful on QOL than those related to the motor cortex or Broca’s area. Conclusions: Tumor proximity to right parietooccipital region are associated with decreased QOL. This should be considered in the management strategies of glioma patients.

Author(s):  
Amy D. Rodriguez

Abstract Purpose: This article introduces two types of prosody in human communication; describes right hemisphere contributions to prosody; describes prosodic deficits associated with right hemisphere damage; and discusses prevalence, quality of life, spontaneous recovery, and treatment of aprosodia. Method: Definitions of affective and linguistic prosody and aprosodia are provided. Results of lesion studies and neuroimaging studies are reviewed to inform the reader of the importance of the right hemisphere in prosody expression and comprehension, as well as to describe patterns of prosodic deficits in individuals with right hemisphere damage. Results and Conclusions: There is a large body of evidence supporting the role of the right hemisphere in affective prosody comprehension and production. Specifically, frontal brain regions and the basal ganglia are associated with aprosodia, suggesting there may be an underlying motor impairment. Because aprosodia is enduring and can impact quality of life, it is important to gain a better understanding of this disorder so that clinicians can accurately diagnose prosodic deficits and provide informed treatment.


2019 ◽  
Vol 21 ◽  
pp. 101658 ◽  
Author(s):  
Lisa Millgård Sagberg ◽  
Daniel Høyer Iversen ◽  
Even Hovig Fyllingen ◽  
Asgeir Store Jakola ◽  
Ingerid Reinertsen ◽  
...  

Medicines ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 112 ◽  
Author(s):  
Michela Iannone ◽  
Agata Janowska ◽  
Valentina Dini ◽  
Giulia Tonini ◽  
Teresa Oranges ◽  
...  

Background: The aims of this review are to analyze the current literature regarding the characteristics and pathophysiological mechanisms of itch in chronic wounds, to assess the impact on quality of life and delayed-healing, to focus on the best strategies of prevention and treatment, to highlight the importance of on-going research in order to fully understand the pathophysiology, and to improve the management of target therapies. Methods: A systematic literature review was performed using MEDLINE, PubMed, Embase, Scopus, ScienceDirect, and the Cochrane Library. We included a total of 11 articles written in English with relevant information on the pathophysiology of itch in chronic wounds and on management strategies. Results: Itch in chronic wounds was found to be correlated with xerosis, larger wound areas, necrotic tissue and amount of exudate, peripheral tissue edema, sclerosis, granulation tissue, contact dermatitis, and bacterial burden, as well as with lower quality of life. Conclusions: Although there are several aspecific pharmacological and non-pharmacological approaches, there appears to be no validated prevention or management strategy for itch in chronic wounds. Further studies are needed to clarify the association and pathophysiology of itch in chronic wounds, to evaluate the safety and efficacy of topical treatments on perilesional skin to reduce itch, to characterize multidimensional sensations of itch in chronic wounds, to identify specific cytokine and chemokine expressions that are correlated to a tailored-based approach, and to develop practical guidelines.


2015 ◽  
Vol 17 (suppl 5) ◽  
pp. v190.4-v191
Author(s):  
Christian Iorio-Morin ◽  
Philippe Goffaux ◽  
Maxime Descoteau ◽  
Kevin Whittingstall ◽  
David Fortin

Ekonomia ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 97-113
Author(s):  
Agnieszka Sadowa

Housing conditions as a determinant of the quality of life of disabled people, based on the example of people with sight dysfunctionOne of the basic needs of a person is to have a place to live. Virtually everyone dreams of having their own place, to relax and feel safe. Such a space is an important place for people with disabilities, because it is often the only place that is tailored to their needs, where they feel safer than in any other spaces. Every citizen of the country has the right to housing, which is provided by numerous docu­ments and regulations.The purpose of this article is to evaluate the impact of housing conditions on the quality of life of people with disabilities. The following thesis has been formulated in the work: the disabled aim to improve the quality of their lives by changing housing conditions.Literature sources have been reviewed to define basic concepts, the results of previous studies have been correlated. After accessing the database, the results of the research carried out in March 2015 by the foundation “Nie widzę problemu” literally meaning “I do not see the problem” with involvement of employees and students of the University of Wroclaw have been compiled.The analysis shows that respondents most often live together with their parents and spend a large part of their income on purchases related to household appliances. As much as 60% of re­spondents do not own a flat. Approximately 68% find the buildings they live in are not suited to their needs, however only 23% of them try to get social housing.Translated by Karolina Riemel


2020 ◽  
Author(s):  
Xiaoxiao Chen ◽  
Qian Xu ◽  
Haijiang Lin ◽  
Jianfu Zhu ◽  
Yue Chen ◽  
...  

Abstract Background: The COVID-19 related lockdown and home confinement might have an important impact on the quality of life in enterprise workers. We investigated the quality of life during the epidemic in enterprise workers who just returned to work, and assessed its potential influencing factors to have a better understanding of the impact of COVID-19 epidemic lockdown and home confinement. Methods: This was a cross-sectional study of enterprise workers conducted in Deqing and Taizhou, Zhejiang Province, China. The Chinese version of EQ5D was used to assess life quality, and information about general characteristics and COVID-19 related factors was collected by a structured questionnaire, which was distributed through the social application “WeChat”. Results: A total of 2,435 participants were enrolled, 59.5% of which worked in Deqing. About 50% of the participants reported worries about the COVID-2019 epidemic and 40.1% had a centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression showed that the quality of life measures was related to physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) in Deqing, and were related to wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and having a centralized or home quarantine (ORad=1.64) in Taizhou,Conclusions: The quality of life for returning enterprise workers in areas with different risks of COVID-19 was affected by different factors. Associated factors identified from this study would help develop proper intervention measures for enterprise workers to reduce the impact of large-scale public health events like the COVID-19 on their quality of life.


2020 ◽  
Author(s):  
Xiaoxiao Chen ◽  
Qian Xu ◽  
Haijiang Lin ◽  
Jianfu Zhu ◽  
Yue Chen ◽  
...  

Abstract Background: The COVID-19 related lockdown and home confinement might have an important impact on the quality of life in enterprise workers. We investigated the quality of life during the epidemic in enterprise workers who just returned to work, and assessed its potential influencing factors to have a better understanding of the impact of COVID-19 epidemic lockdown and home confinement.Methods: This was a cross-sectional study of enterprise workers conducted in Deqing and Taizhou, Zhejiang Province, China. The Chinese version of EQ5D was used to assess life quality, and information about general characteristics and COVID-19 related factors was collected by a structured questionnaire, which was distributed through the social application “WeChat”.Results: A total of 2,435 participants were enrolled, 59.5% of which worked in Deqing. About 50% of the participants reported worries about the COVID-2019 epidemic and 40.1% had a centralized or home quarantine during the epidemic. The mean EQ-5D score and VAS were 0.990 and 93.5. Multiple logistic regression showed that the quality of life measures was related to physical activities (ORad=0.46) and keeping home ventilation (ORad=0.04) in Deqing, and were related to wearing a mask when going out (ORad=0.35), keeping home ventilation (ORad=0.16), unmarried status (ORad=2.38) and having a centralized or home quarantine (ORad=1.64) in Taizhou,Conclusions: The quality of life for returning enterprise workers in areas with different risks of COVID-19 was affected by different factors. Associated factors identified from this study would help develop proper intervention measures for enterprise workers to reduce the impact of large-scale public health events like the COVID-19 on their quality of life.


2009 ◽  
Vol 1 (1) ◽  
pp. 75-105 ◽  
Author(s):  
Matias D Cattaneo ◽  
Sebastian Galiani ◽  
Paul J Gertler ◽  
Sebastian Martinez ◽  
Rocio Titiunik

We investigate the impact of a large-scale Mexican program to replace dirt floors with cement floors on child health and adult happiness. We find that replacing dirt floors with cement significantly improves the health of young children measured by decreases in the incidence of parasitic infestations, diarrhea, and the prevalence of anemia, and an improvement in children's cognitive development. Additionally, we find significant improvements in adult welfare measured by increased satisfaction with their housing and quality of life, as well as by lower scores on depression and perceived stress scales. (JEL I12, I31, J13, O15)


2021 ◽  
Vol 26 (1) ◽  
pp. 30-34
Author(s):  
Leona Cilar ◽  
Špela Polak ◽  
Barbara Kegl

Introduction: Chronic inflammatory bowel disease is a chronic lifelong disease with various triggers, intermediate longer and shorter remissions. Parents need to know what kind of nutrition the child with chronic inflammatory bowel disease needs because they must be able to make the right decisions regarding the child‘s diet. The right choice of diet gives a child enough energy in their daily and enables the quality life. They must enjoy a healthy balanced diet so that they receive all the nutrients the body needs. In our work, we presented chronic inflammatory bowel disease in children and parents’ assessment of the child’s quality of life. Methods: We chose a quantitative methodology to establish the impact of diet on the quality of life of the child with chronic inflammatory bowel disease. To describe and define the problem, we used a descriptive method. A structured measurement instrument was based on a review of the relevant foreign and domestic literature. Statistical data analysis was performed using descriptive and inferential statistics. Data were collected by a non-random and occasional sampling survey. Results: We found that most children whose parents participated in this research have Crohn’s disease (n = 20; 50%) and ulcerative colitis (n = 16; 40%). The type of food that is harmful to the child is fatty food (n = 33; 83%), followed by spicy food (n = 32; 80%) and acidic food (n = 10; 25%). According to the parents’ assessment, children with chronic inflammatory bowel disease have good (n = 22; 55%) health. We found that physicians provide parents with the most necessary nutrition information. Through evaluation of the parents, we found that there is no statistically significant correlation between the general assessment of a child’s health and the type of chronic inflammatory bowel disease (X² (2) = 5.925, p = 0.052). Also, there is no statistically significant correlation between the eating pattern and parents ’assessment of their child’s quality of life (U = 38.00, p. = 1.00). Discussion: The health care providers have an important role to play in giving appropriate information to parents to ensure the quality of life of the child. She teaches parents and children about living with chronic inflammatory bowel disease and emphasizes the importance of nutrition, which greatly contributes to a better quality of life.


2020 ◽  
Vol 14 (08) ◽  
pp. 812-816
Author(s):  
Huda H Alsayedahmed

COVID-19 is a novel coronavirus that emerged in Wuhan-China during the last quarter in 2019 and caused an infectious respiratory disease pandemic. The strategy of “Attack and Defend” was attempted to mitigate COVID-19 crisis worldwide. A list of precautionary measures were set by healthcare professional experts to protect public from infection, social physical distancing measures being the most efficient. On the other hand, Occupational Safety and Health Administration (OSHA) has established protective guidelines for healthcare workers to guarantee a healthy workplace and safe environment. The physical distancing measures have obviously reshaped the relationship between family members leading to better quality of family life. Meanwhile, travel suspension also led to slightly higher health standards with less air pollution, lower traffic induced stress levels and subsequently a greener footprint. Herein, we intend to highlight the impact of COVID-19 pandemic protective measures on family connections, as well as on environmental health. Moreover, we aimed at pointing out the effect on Saudi Arabian cultural and humanitarian behavior in dealing with the pandemic under the governance care of the custodian of the two holy mosques; King Salman Al-Saud. In fact, a combination of restrictive and protective measures is the most efficient to curb COVID-19 spread. In addition to improving the quality of social life, this pandemic revealed a healthier climate, which will certainly be visible on a large scale. Certainly, all together with solidarity we will be able to restrain COVID-19 pandemic and have a better quality of life.


Sign in / Sign up

Export Citation Format

Share Document