scholarly journals Iron bioavailability: UK Food Standards Agency workshop report

2006 ◽  
Vol 96 (5) ◽  
pp. 985-990 ◽  
Author(s):  
Mamta Singh ◽  
Peter Sanderson ◽  
Richard F. Hurrell ◽  
Susan J. Fairweather-Tait ◽  
Catherine Geissler ◽  
...  

The UK Food Standards Agency convened a group of expert scientists to review current research investigating factors affecting iron status and the bioavailability of dietary iron. Results presented at the workshop show menstrual blood loss to be the major determinant of body iron stores in premenopausal women. In the presence of abundant and varied food supplies, the health consequences of lower iron bioavailability are unclear and require further investigation.

2003 ◽  
Vol 90 (2) ◽  
pp. 473-479 ◽  
Author(s):  
Peter Sanderson ◽  
Helene McNulty ◽  
Pierpaolo Mastroiacovo ◽  
Ian F. W. McDowell ◽  
Alida Melse-Boonstra ◽  
...  

The UK Food Standards Agency convened a group of expert scientists to review current research investigating folate bioavailability. The workshop aimed to overview current research and establish priorities for future research. Discrepancies were observed in the evidence base for folate bioavailability, especially with regard to the relative bioavailability of natural folates compared with folic acid. A substantial body of evidence shows folic acid to have superior bioavailability relative to food folates; however, the exact relative bioavailability still needs to be determined, and in particular with regard to mixed diets. The bioavailability of folate in a mixed diet is probably not a weighted average of that in the various foods consumed; thus the workshop considered that assessment of folate bioavailability of whole diets should be a high priority for future research.


2004 ◽  
Vol 91 (2) ◽  
pp. 315-322 ◽  
Author(s):  
Peter Sanderson ◽  
Ian T. Johnson ◽  
John C. Mathers ◽  
Hilary J. Powers ◽  
C. Stephen Downes ◽  
...  

The UK Food Standards Agency convened a group of expert scientists to review current research investigating emerging diet-related surrogate end points for colorectal cancer (CRC). The workshop aimed to overview current research and establish priorities for future research. The workshop considered that the validation of current putative diet-related surrogate end points for CRC and the development of novel ones, particularly in the emerging fields of proteomics, genomics and epigenomics, should be a high priority for future research.


2010 ◽  
Vol 103 (11) ◽  
pp. 1688-1694 ◽  
Author(s):  
Emma Peacock ◽  
John Stanley ◽  
Philip C. Calder ◽  
Susan A. Jebb ◽  
Frank Thies ◽  
...  

This report summarises a workshop convened by the UK Food Standards Agency (FSA) on 14 October 2008 to discuss current FSA-funded research on carbohydrates and cardiovascular health. The objective of this workshop was to discuss the results of recent research and to identify any areas which could inform future FSA research calls. This workshop highlighted that the FSA is currently funding some of the largest, well-powered intervention trials investigating the type of fat and carbohydrate, whole grains and fruit and vegetables, on various CVD risk factors. Results of these trials will make a substantive contribution to the evidence on diet and cardiovascular risk.


Nutrition ◽  
2008 ◽  
Vol 24 (7-8) ◽  
pp. 638-645 ◽  
Author(s):  
Michael Hoppe ◽  
Agneta Sjöberg ◽  
Leif Hallberg ◽  
Lena Hulthén

2019 ◽  
Vol 41 (1) ◽  
pp. 121-130 ◽  
Author(s):  
Susan Fairweather-Tait ◽  
Cornelia Speich ◽  
Comlan Evariste S. Mitchikpè ◽  
Jack R. Dainty

Background: Reference intakes for iron are derived from physiological requirements, with an assumed value for dietary iron absorption. A new approach to estimate iron bioavailability, calculated from iron intake, status, and requirements was used to set European dietary reference values, but the values obtained cannot be used for low- and middle-income countries where diets are very different. Objective: We aimed to test the feasibility of using the model developed from United Kingdom and Irish data to derive a value for dietary iron bioavailability in an African country, using data collected from women of child-bearing age in Benin. We also compared the effect of using estimates of iron losses made in the 1960s with more recent data for whole body iron losses. Methods: Dietary iron intake and serum ferritin (SF), together with physiological requirements of iron, were entered into the predictive model to estimate percentage iron absorption from the diet at different levels of iron status. Results: The results obtained from the 2 different methods for calculating physiological iron requirements were similar, except at low SF concentrations. At a SF value of 30 µg/L predicted iron absorption from the African maize-based diet was 6%, compared with 18% from a Western diet, and it remained low until the SF fell below 25 µg/L. Conclusions: We used the model to estimate percentage dietary iron absorption in 30 Beninese women. The predicted values agreed with results from earlier single meal isotope studies; therefore, we conclude that the model has potential for estimating dietary iron bioavailability in men and nonpregnant women consuming different diets in other countries.


2005 ◽  
Vol 75 (6) ◽  
pp. 375-384 ◽  
Author(s):  
Janet R. Hunt

Iron deficiency, a global health problem, impairs reproductive performance, cognitive development, and work capacity. One proposed strategy to address this problem is the improvement of dietary iron bioavailability. Knowledge of the molecular mechanisms of iron absorption is growing rapidly, with identification of mucosal iron transport and regulatory proteins. Both body iron status and dietary characteristics substantially influence iron absorption, with minimal interaction between these two factors. Iron availability can be regarded mainly as a characteristic of the diet, but comparisons between human studies of iron availability for absorption require normalization for the iron status of the subjects. The dietary characteristics that enhance or inhibit iron absorption from foods have been sensitively and quantitatively determined in human studies employing iron isotopes. People with low iron status can substantially increase their iron absorption from diets with moderate to high availability. But while iron supplementation and fortification trials can effectively increase blood indices of iron status, improvements in dietary availability alone have had minimal influence on such indices within several weeks or months. Plentiful, varied diets are the ultimate resolution to iron deficiency. Without these, more modest food-based approaches to human iron deficiency likely will need to be augmented by dietary iron fortification.


2004 ◽  
Vol 91 (3) ◽  
pp. 491-500 ◽  
Author(s):  
Peter Sanderson ◽  
Margreet Olthof ◽  
Robert F. Grimble ◽  
Philip C. Calder ◽  
Bruce A. Griffin ◽  
...  

The UK Food Standards Agency convened a group of expert scientists to review current research investigating the effect of dietary lipids on vascular function. The workshop highlighted the need for intervention studies to be sufficiently powered for these measures and that they should be corroborated with other, more validated, risk factors for CVD. Work presented at the workshop suggested a beneficial effect of long-chain n-3 PUFA and a detrimental effect of trans fatty acids. The workshop also considered the importance of the choice of study population in dietary intervention studies and that ‘at risk’ subgroups within the general population may be more appropriate than subjects that are unrepresentatively healthy.


2007 ◽  
Vol 98 (6) ◽  
pp. 1299-1304 ◽  
Author(s):  
Peter Sanderson ◽  
Elaine Stone ◽  
Young-In Kim ◽  
John C. Mathers ◽  
Ellen Kampman ◽  
...  

The UK Food Standards Agency convened a group of expert scientists to review current research investigating folate and colo-rectal cancer risk. The workshop aimed to examine current research and establish research priorities. The timing of folate exposure with respect to carcinogenesis, as well as the dose and form of folate, were considered key issues for future research. Also, the need to study further the influence of genetically defined subgroups was highlighted for future research.


PLoS ONE ◽  
2014 ◽  
Vol 9 (10) ◽  
pp. e111824 ◽  
Author(s):  
Jack R. Dainty ◽  
Rachel Berry ◽  
Sean R. Lynch ◽  
Linda J. Harvey ◽  
Susan J. Fairweather-Tait

2021 ◽  
Vol 9 (5) ◽  
pp. 53
Author(s):  
Rayan Sharka ◽  
Jonathan P. San Diego ◽  
Melanie Nasseripour ◽  
Avijit Banerjee

Aims: This study aimed to identify the risk factors of using DSM to provide an insight into the inherent implications this has on dental professionals in practice and trainee professionals’ education. Materials and methods: Twenty-one participants (10 dental professionals and 11 undergraduate and postgraduate dental students) participated in this qualitative study using semi-structured interviews in a dental school in the UK. The interviews were analysed and categorised into themes, some of which were identified from previous literature (e.g., privacy and psychological risks) and others emerged from the data (e.g., deceptive and misleading information). Results: The thematic analysis of interview transcripts identified nine perceived risk themes. Three themes were associated with the use of DSM in the general context, and six themes were related to the use of DSM in professional and education context. Conclusions: This study provided evidence to understand the risk factors of using DSM in dental education and the profession, but the magnitude of these risks on the uptake and usefulness of DSM needs to be assessed.


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