Integrated Management of Complex Intracranial Lesions

2021 ◽  

Large intracranial lesions are among the most complex and dangerous lesions encountered by neurosurgeons, and a single neurosurgical approach often does not provide a large or safe enough corridor for effective treatment. A combined approach to these surgeries, incorporating open, endoscopic, vascular and keyhole techniques can be more successful. This comprehensive text describes in detail how to select the most appropriate approaches, as well as how to avoid any complications that may arise. High quality videos of the techniques described are available through an online version on Cambridge Core, accessible via the code printed on the inside of the cover. With over 150 colour images supporting the text, this is a definitive reference for anyone involved in intracranial tumor or vascular surgery.

2020 ◽  
Vol 15 (2) ◽  
pp. 93-121
Author(s):  
Vasileios Tzikoulis ◽  
Areti Gkantaifi ◽  
Filippo Alongi ◽  
Nikolaos Tsoukalas ◽  
Haytham Hamed Saraireh ◽  
...  

Background: Radiation Therapy (RT) is an established treatment option for benign intracranial lesions. The aim of this study is to display an update on the role of RT concerning the most frequent benign brain lesions and tumors. Methods: Published articles about RT and meningiomas, Vestibular Schwannomas (VSs), Pituitary Adenomas (PAs), Arteriovenous Malformations (AVMs) and craniopharyngiomas were reviewed and extracted data were used. Results: In meningiomas RT is applied as an adjuvant therapy, in case of patientrefusing surgery or in unresectable tumors. The available techniques are External Beam RT (EBRT) and stereotactic ones such as Stereotactic Radiosurgery (SRS), Fractionated Stereotactic RT (FSRT), Intensity Modulated RT (IMRT) and proton-beam therapy. The same indications are considered in PAs, in which SRS and FSRT achieve excellent tumor control rate (92-100%), acceptable hormone remission rates (>50%) and decreased Adverse Radiation Effects (AREs). Upon tumor growth or neurological deterioration, RT emerges as alone or adjuvant treatment against VSs, with SRS, FSRT, EBRT or protonbeam therapy presenting excellent tumor control growth (>90%), facial nerve (84-100%), trigeminal nerve (74-99%) and hearing (>50%) preservation. SRS poses an effective treatment modality of certain AVMs, demonstrating a 3-year obliteration rate of 80%. Lastly, a combination of microsurgery and RT presents equal local control and 5-year survival rate (>90%) but improved toxicity profile compared to total resection in case of craniopharyngiomas. Conclusion: RT comprises an effective treatment modality of benign brain and intracranial lesions. By minimizing its AREs with optimal use, RT projects as a potent tool against such diseases.


2018 ◽  
pp. 57-77
Author(s):  
Stephen M. Rutherford

This chapter examines the medical challenges posed by the increased number of gunshot wounds during the civil wars, and sets out the changes in the way these wounds were treated. The treatment of battlefield wounds expounded in surgeons’ manuals, is placed in context with what we now understand about the biology, pathology and effective treatment methods for wounds. The techniques used by the civil-war surgeon are compared with those of later periods. Despite a lack of understanding of microbiology, physiology and, in many cases, anatomy, many methods employed by civil-war military surgeons reflect good contemporary surgical practice. Despite the lack of antibiotics, anaesthetics, hygienic environments and high-quality surgical implements, survival rates from injuries on the field arrear to have been considerable, if treated. In developing treatments for the problems posed by gunshot wounds, some civil-war surgeons used an evidence-based approach, and laid the foundations for much modern surgical practice.


2014 ◽  
Vol 596 ◽  
pp. 678-681
Author(s):  
Ya Ning Yuan ◽  
Ming Meng

In order to achieve the objectives of energy-saving and emission reduction for modern buildings and provide high quality power supply, a DC microgrid system of thermoelectric energy comprehensive control is proposed. The system includes two subsystems of electric energy and heat energy system, and realizes electric and heat energy transformation and combination through cogeneration unit and electronic heating device. To achieve efficient use of energy, integrated management strategies is also proposed. Distributed generations are controlled by the maximum power tracking strategy, and the hybrid energy storage system uses droop control strategy to stabilize DC bus voltage. In the connection point between the grid and microgrid, the bidirectional converter uses vector decoupling control strategy with double closed loop for pulse width modulation (PWM) to solve the problem of bidirectional power flow with the grid. The simulation results indicate that the system can provide high quality, energy saving, stable power for the modern building.


Author(s):  
Alireza Rezaee ◽  
Omid Bozorg-Haddad ◽  
Ronny Brendtsson ◽  
Vijay P. Singh

Abstract Improper utilization of water resources has the potential to result in reduced availability of high-quality water and adverse effects on societal development. In fact, what appears to be a serious gap in comprehensive water resources studies is the lack of a coherent approach that can link different social, economic and environmental parts within the framework of the integrated water management paradigm to extract strategies and operational plans. Comprehensive water resources management (CWRM) is a process that intends to develop and manage water, land and other resources in a way that maximizes the social and economic well-being of human societies, without compromising the integrity and sustainability of vital ecosystems and future benefits. This chapter discusses the definitions of integrated and comprehensive water resources management describing the steps of using integrated management in practical examples.


Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 790
Author(s):  
Giuliocesare Casari Bariani ◽  
Lan Zhou ◽  
Simone Poggesi ◽  
Rakesh Mittapalli ◽  
Marisa Manzano ◽  
...  

Celiac diseases are a group of gluten ingestion-correlated pathologies that are widespread and, in some cases, very dangerous for human health. The only effective treatment is the elimination of gluten from the diet throughout life. Nowadays, the food industries are very interested in cheap, easy-to-handle methods for detecting gluten in food, in order to provide their consumers with safe and high-quality food. Here, for the first time, the manufacture of controlled micropatterns of annealed gold nanoislands (AuNIs) on a single QCM crystal (QCM-color) and their biofunctionalization for the specific detection of traces of gliadin is reported. In addition, the modified quartz crystal with a TEM grid and 30 nm Au (Q-TEM grid crystal) is proposed as an acoustic sensitive biosensing platform for the rapid screening of the gliadin content in real food products.


Polar Record ◽  
2012 ◽  
Vol 48 (4) ◽  
pp. 305-305
Author(s):  
Ian R. Stone

Attentive readers of Polar Record will have noticed that, since the issue for October 2011 (Volume 47 Issue 4), no book reviews have appeared in the journal's issues. The reason for this is simply that not only has the journal been receiving a large number of high-quality submissions in the form of articles and notes but it has also published two special themed issues in the last few months. This meant there was simply no space for book reviews and obituaries taking into consideration the space limitations of the hard copy issues. This problem is alleviated somewhat by the fact that all contributions are published online in FirstView (http://journals.cambridge.org/action/displayJournal?jid=POL) before appearing in an issue, and book reviews and obituaries published in Polar Record have been free to view online since 2010. Furthermore contributions published in FirstView may be cited in exactly the same manner as contributions published in an issue, but using the doi number rather than volume and page numbers. To rationalise the situation, it has been decided that articles and notes will continue to appear in hard copy, albeit at some remove from their publication in FirstView, while book reviews, obituaries, etc will only appear in the online version of the issue.


Author(s):  
[No authors Listed]

There was an error in the description of GLORIA-AF registry program at page 10 in this Supplement by Casolo et al. [Farmeconomia. Health economics and therapeutic pathways 2019; 20(Suppl 1): 3-16; https://doi.org/10.7175/fe.v20i1S.1454]. The online version has been corrected on February 12, 2020.


Open Medicine ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 270-278 ◽  
Author(s):  
Wolfgang Lederer ◽  
Astrid Grams ◽  
Raimund Helbok ◽  
Martina Stichlberger ◽  
Reto Bale ◽  
...  

AbstractInterventional radiology is a rapidly growing discipline with an expanding variety of indications and techniques in pediatric and adult patients. Accordingly, the number of procedures during which monitoring either under sedation or under general anesthesia is needed is increasing. In order to ensure high-quality care as well as patient comfort and safety, implementation of anes-thesiology practice guidelines in line with institutional radiology practice guidelines is paramount [1]. However, practice guidelines are no substitute for lack of communi-cation between specialties.Interdisciplinary indications within neurosciences call for efficient co-operation among radiology, neurology, neurosurgery, vascular surgery, anesthesiology and intensive care. Anesthesia team and intensive care personnel should be informed early and be involved in coordinated planning so that optimal results can be achieved under minimized risks and pre-arranged complication management.


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