P.1.009 Misdiagnosis of bipolar disorder as unipolar depression: A problematic differential diagnosis in clinical practice

2004 ◽  
Vol 14 ◽  
pp. S178
Author(s):  
M.D. Stensland ◽  
N. deLay ◽  
M. Ciaglia ◽  
S. Visawanathan
Keyword(s):  
Bipolar Disorder ◽  
Differential Diagnosis ◽  
Clinical Practice ◽  
Unipolar Depression

scholarly journals Unipolar and bipolar depression: different or the same?

2011 ◽  
Vol 199 (4) ◽  
pp. 272-274 ◽  
Author(s):  
Daniel J. Smith ◽  
Nick Craddock
Keyword(s):  
Bipolar Disorder ◽  
Clinical Practice ◽  
Bipolar Depression ◽  
Unipolar Depression ◽  
Clear Cut ◽  
New Thinking ◽  
The Relationship

SummaryThe diagnostic boundary between recurrent unipolar depression and bipolar disorder may not be clear-cut and, further, the symptoms of unipolar depression compared with bipolar depression (although similar) are subtly different. Here we review the potential implications for clinical practice and research of new thinking about the relationship between recurrent unipolar depression and bipolar disorder.

Should the bipolar disorders be modelled dimensionally or categorically?

2017 ◽  
Author(s):  
Gordon Parker ◽  
Amelia Paterson
Keyword(s):  
Bipolar Disorder ◽  
Clinical Practice ◽  
Bipolar Disorders ◽  
Unipolar Depression ◽  
Treatment Decisions ◽  
The Other ◽  
Dimensional Model ◽  
Categorical Model ◽  
History Of ◽  
Categorical Models

Historically, there have been categorical models of bipolar disorder and dimensional models of bipolar disorder. This chapter seeks to outline the history of these models as well as some recent supporting research. The models are evaluated in two ways; how well they reflect the underlying nature of bipolar disorder, and how useful they are to the patient and to the clinician in undertaking treatment decisions. The dimensional model posits that depression and bipolar lie on a continuum with pure unipolar depression at one end, bipolar disorder at the other, and some experience of highs without diagnosable (hypo)mania in-between. The categorical model posits that depression and bipolar are entirely separate conditions and that bipolar I and II are separate conditions. It is the position of the authors that the categorical model is a better reflection of the underlying nature of bipolar disorder and has proved more useful in clinical practice.

POST-TRANSFUSION PURPURA VS. HEPARIN-INDUCED THROMBOCYTOPENIA: DIFFERENTIAL DIAGNOSIS IN CLINICAL PRACTICE

2000 ◽  
Vol 10 (4) ◽  
pp. 323-324 ◽  
Author(s):  
F. Araujo ◽  
J. J. Sa ◽  
V. Araujo ◽  
M. Lopes ◽  
L. M. Cunha-Ribeiro
Keyword(s):  
Differential Diagnosis ◽  
Clinical Practice ◽  
Heparin Induced Thrombocytopenia

Different temperament and character dimensions correlate with panic disorder comorbidity in bipolar disorder and unipolar depression

2008 ◽  
Vol 22 (8) ◽  
pp. 1421-1426 ◽  
Author(s):  
Marco Mula ◽  
Stefano Pini ◽  
Palmiero Monteleone ◽  
Paolo Iazzetta ◽  
Matteo Preve ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Panic Disorder ◽  
Unipolar Depression

scholarly journals Validity and reliability of the Structured Clinical Interview for Mood Spectrum: Brazilian version (SCIMOODS-VB)

2011 ◽  
Vol 33 (1) ◽  
pp. 64-67 ◽  
Author(s):  
Roberto Ratzke ◽  
Doris Hupfeld Moreno ◽  
Clarice Gorenstein ◽  
Ricardo Alberto Moreno
Keyword(s):  
Bipolar Disorder ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Intraclass Correlation ◽  
Unipolar Depression ◽  
Brazilian Portuguese ◽  
Clinical Interview ◽  
Stepwise Discriminant Analysis ◽  
Cutoff Score ◽  
Major Depressive

OBJECTIVE: The aim of this study was to translate the Structured Clinical Interview for Mood Spectrum into Brazilian Portuguese, measuring its reliability, validity, and defining scores for bipolar disorders. METHOD: Questionnaire was translated (into Brazilian Portuguese) and back-translated into English. Sample consisted of 47 subjects with bipolar disorder, 47 with major depressive disorder, 18 with schizophrenia and 22 controls. Inter-rater reliability was tested in 20 subjects with bipolar disorder and MDD. Internal consistency was measured using the Kuder Richardson formula. Forward stepwise discriminant analysis was performed. Scores were compared between groups; manic (M), depressive (D) and total (T) threshold scores were calculated through receiver operating characteristic (ROC) curves. RESULTS: Kuder Richardson coefficients were between 0.86 and 0.94. Intraclass correlation coefficient was 0.96 (CI 95 % 0.93-0.97). Subjects with bipolar disorder had higher M and T, and similar D scores, when compared to major depressive disorder (ANOVA, p < 0.001). The sub-domains that best discriminated unipolar and bipolar subjects were manic energy and manic mood. M had the best area under the curve (0.909), and values of M equal to or greater than 30 yielded 91.5% sensitivity and 74.5% specificity. CONCLUSION: Structured Clinical Interview for Mood Spectrum has good reliability and validity. Cut-off of 30 best differentiates subjects with bipolar disorder vs. unipolar depression. A cutoff score of 30 or higher in the mania sub-domain is appropriate to help make a distinction between subjects with bipolar disorder and those with unipolar depression.

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