Nicotine and cotinine affect the release of vasoactive factors by trophoblast cells and human umbilical vein endothelial cells

2011 ◽  
Vol 2011 ◽  
pp. 23-24
Author(s):  
M.T. Watkins
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
Trophoblast Cells ◽  
Human Umbilical Vein ◽  
Vasoactive Factors ◽  
Umbilical Vein Endothelial Cells

scholarly journals The role of nitric oxide in the outgrowth of trophoblast cells on human umbilical vein endothelial cells

2015 ◽  
Vol 54 (3) ◽  
pp. 227-231 ◽  
Author(s):  
Kuan-Hao Tsui ◽  
Hsin-Yang Li ◽  
Jiin-Tsuey Cheng ◽  
Yen-Jen Sung ◽  
Ming-Shyen Yen ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Endothelial Cells ◽  
Umbilical Vein ◽  
Trophoblast Cells ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells

Ghrelin in vitro modulates vasoactive factors in human umbilical vein endothelial cells

2007 ◽  
Vol 88 (4) ◽  
pp. 1158-1166 ◽  
Author(s):  
Francesca Minici ◽  
Fiorella Miceli ◽  
Federica Tiberi ◽  
Anna Tropea ◽  
Mariateresa Orlando ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
Human Umbilical Vein ◽  
Vasoactive Factors ◽  
Umbilical Vein Endothelial Cells

Studies of the Factor Xa-Dependent Inhibitor of Factor VIIa/Tissue Factor (Extrinsic Pathway Inhibitor) from Cell Supernates of Cultured Human Umbilical Vein Endothelial Cells

1989 ◽  
Vol 61 (01) ◽  
pp. 101-105 ◽  
Author(s):  
Bonnie J Warn-Cramer ◽  
Fanny E Almus ◽  
Samuel I Rapaport
Keyword(s):  
Molecular Weight ◽  
Endothelial Cells ◽  
Tissue Factor ◽  
Phorbol Ester ◽  
Umbilical Vein ◽  
Primary Cultures ◽  
Factor Xa ◽  
Extrinsic Pathway ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells

SummaryCultured human umbilical vein endothelial cells (HUVEC) have been reported to produce extrinsic pathway inhibitor (EPI), the factor Xa-dependent inhibitor of factor VHa/tissue factor (TF). We examined the release of this inhibitor from HUVEC as a function of their growth state and in response to the induction of endothelial cell TF activity. HUVEC constitutively produced significant amounts of EPI at all stages of their growth in culture including the post-confluent state. Rate of release varied over a 3-fold range for primary cultures from 12 different batches of pooled umbilical cord cells. Constitutive EPI release was unaltered during a 6 hour period of induction of TF activity with thrombin or phorbol ester but slowed during longer incubation of the cells with phorbol ester. Whereas plasma contains two molecular weight forms of EPI, only the higher of these two molecular weight forms was demonstrable by Western analysis of HUVEC supernatants with 125I-factor Xa as the ligand.

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