Substitution of Standard Soybean Oil with Olive Oil-Based Lipid Emulsion in Parenteral Nutrition: Comparison of Vascular, Metabolic, and Inflammatory Effects

2012 ◽  
Vol 2012 ◽  
pp. 212-213
Author(s):  
J.M. Daly
Keyword(s):  
Parenteral Nutrition ◽  
Soybean Oil ◽  
Olive Oil ◽  
Lipid Emulsion

scholarly journals Substitution of Standard Soybean Oil with Olive Oil-Based Lipid Emulsion in Parenteral Nutrition: Comparison of Vascular, Metabolic, and Inflammatory Effects

2011 ◽  
Vol 96 (10) ◽  
pp. 3207-3216 ◽  
Author(s):  
Joselita Siqueira ◽  
Dawn Smiley ◽  
Christopher Newton ◽  
Ngoc-Anh Le ◽  
Aidar R. Gosmanov ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Soybean Oil ◽  
Olive Oil ◽  
Lipid Emulsion

Substitution of Standard Soybean Oil with Olive Oil-Based Lipid Emulsion in Parenteral Nutrition: Comparison of Vascular, Metabolic and Inflammatory Effects

2011 ◽  
pp. OR04-6-OR04-6
Author(s):  
Dawn Smiley ◽  
Joselita Siqueira ◽  
Aidar Gosmanov ◽  
Christopher Newton ◽  
Limin Peng ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Soybean Oil ◽  
Olive Oil ◽  
Lipid Emulsion

scholarly journals Fish Oil Lipid Emulsion-Associated Sea-Blue Histiocyte Syndrome in a Pediatric Patient

2015 ◽  
Vol 20 (3) ◽  
pp. 217-221
Author(s):  
Ting Ting Wu ◽  
David S. Hoff
Keyword(s):  
Bone Marrow ◽  
Parenteral Nutrition ◽  
Fish Oil ◽  
Soybean Oil ◽  
Total Parenteral Nutrition ◽  
Pediatric Patient ◽  
Lipid Emulsion

A syndrome of hepatosplenomegaly, thrombocytopenia, and anemia and the presence of sea-blue histiocytes in bone marrow has been associated with parenteral soybean oil administration in patients receiving long-term total parenteral nutrition (TPN). A case is described here where this syndrome was observed in a pediatric patient who received long-term parenteral fish oil nutrition.

scholarly journals Intradialytic parenteral nutrition: comparison of olive oil versus soybean oilbasedlipid emulsions

2006 ◽  
Vol 95 (1) ◽  
pp. 152-159 ◽  
Author(s):  
Noël J. M. Cano ◽  
Yannick Saingra ◽  
Anne-Marie Dupuy ◽  
Anne-Marie Lorec-Penet ◽  
Henri Portugal ◽  
...  
Keyword(s):  
Nutritional Status ◽  
Parenteral Nutrition ◽  
Soybean Oil ◽  
Olive Oil ◽  
Hdl Cholesterol ◽  
Apo B ◽  
Lipoprotein A ◽  
Inflammatory Status ◽  
Apo E ◽  
Intradialytic Parenteral Nutrition

Lipid, oxidative and inflammatory parameters are frequently altered in dialysis patients and may be worsened by intravenous lipid emulsions (ILE). We assessed the efficacy and tolerance of olive as compared with standard soybean oil-based ILE during intradialytic parenteral nutrition (IDPN). IDPN mixtures containing amino acids, glucose, and either olive oil (OO group,n17) or soybean oil-based ILE (SO group,n18) were administered in a 5-week randomized, double-blind study. On days 0 and 35, patients' nutritional status was assessed by BMI, normalized protein catabolic rate, predialytic creatinine, serum albumin and transthyretin; lipid metabolism by plasma LDL- and HDL-cholesterol, triacylglycerols, phospholipids, apo A-I, A-II, B, C-II, C-III, E and lipoprotein (a); oxidative status by α-tocopherol, retinol, selenium, glutathione peroxidase, malondialdehyde and advanced oxidized protein products; inflammatory status by serum C-reactive protein, orosomucoid, IL-2 and IL-6. No serious adverse event was observed. Significant changes were observed from day 0 to day 35 (P<0·05): nutritional criteria improved (albumin in OO; albumin, transthyretin and creatinine in SO); LDL-cholesterol, apo B, C-II, C-III and apo A-I/A-II ratio increased in both groups. HDL-cholesterol decreased in OO; apo E increased and lipoprotein (a) decreased in SO; α-tocopherol/cholesterol ratio increased in OO; malondialdehyde decreased in both groups; IL-2 increased in both groups. The between-group comparison only showed the following differences: α-tocopherol/cholesterol increased in OO; lipoprotein (a) decreased in SO. From these data, it was concluded that OO- and SO-based IDPNs similarly improved nutritional status and influenced plasma lipid, oxidative, inflammatory and immune parameters.

Morbidity Outcomes of Very Low Birth Weight Neonates Receiving Parenteral Nutrition with Fish Oil Enriched Lipid Emulsion or Lipid Emulsion with Soybean Oil: An Observational Study

2020 ◽  
Author(s):  
José Uberos ◽  
Sara Jiménez-Montilla ◽  
Manuel Molina-Oya ◽  
Pelayo Nieto-Gómez ◽  
Isabel Cubero Millan
Keyword(s):  
Birth Weight ◽  
Vitamin E ◽  
Low Birth Weight ◽  
Observational Study ◽  
Parenteral Nutrition ◽  
Soybean Oil ◽  
Lipid Emulsion ◽  
Very Low Birth Weight ◽  
Alternative Formulation ◽  
Oil Composition

AbstractIntralipid (Fresenius Kabi) was the most commonly used lipid emulsion in parenteral nutrition (PN), with a 100% soybean oil composition, a low vitamin E content, and a ω-6: ω-3 ratio of 7:1. A recent alternative formulation is SMOFlipid (Fresenius Kabi), with a ω-6: ω-3 ratio of 5:2 and higher vitamin E content. A retrospective observational study was conducted to determine neonatal morbidity in very low birth weight (VLBW) premature infants during two periods: P1, when PN was based exclusively on Intralipid, and P2, when only SMOFlipid was supplied. In total, 170 VLBW neonates were analyzed, of whom 103 received PN for more than 6 days, 56 during P1, and 47 during P2. In both periods, the antenatal and neonatal characteristics of the cohort were comparable. In this analysis, the prevalence of associated comorbidities was determined. During P2, there were fewer cases of moderate to severe bronchopulmonary dysplasia (BPD) and of cholestasis, but more cases of late sepsis, mainly Staphylococcus epidermidis. No changes in the prevalence of other neonatal comorbidities were observed. We believe that the SMOFlipid used in PN could discreetly improve the prevalence of cholestasis or BPD.

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