scholarly journals 234. Long Term Effects of pcDNA3_VEGF165 Intramyocardial Transfer after Experimental Myocardial Infarction in the Rat Scar Tissue Extracellular Matrix

2006 ◽  
Vol 13 ◽  
pp. S90
Author(s):  
Fabio D. Mataveli ◽  
Sang W. Han ◽  
Aline Mendes ◽  
Rose Kanashiro ◽  
Paulo Tucci ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Extracellular Matrix ◽  
Scar Tissue ◽  
Experimental Myocardial Infarction ◽  
Long Term Effects

Optimization of a decellularization protocol of porcine tracheas. Long-term effects of cryopreservation. A histological study

2021 ◽  
pp. 039139882110089
Author(s):  
Lara Milian ◽  
María Sancho-Tello ◽  
Joan Roig-Soriano ◽  
Giovanna Foschini ◽  
Néstor J Martínez-Hernández ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Histological Study ◽  
Biomechanical Properties ◽  
Elastic Fibers ◽  
Appreciable Effect ◽  
Long Term Effects ◽  
Minimal Impact ◽  
Biomechanical Effect ◽  
Triton X

Objective: The aim of this study was to optimize a decellularization protocol in the trachea of Sus scrofa domestica (pig) as well as to study the effects of long-term cryopreservation on the extracellular matrix of decellularized tracheas. Methods: Porcine tracheas were decellularized using Triton X-100, SDC, and SDS alone or in combination. The effect of these detergents on the extracellular matrix characteristics of decellularized porcine tracheas was evaluated at the histological, biomechanical, and biocompatibility level. Morphometric approaches were used to estimate the effect of detergents on the collagen and elastic fibers content as well as on the removal of chondrocytes from decellularized organs. Moreover, the long-term structural, ultrastructural, and biomechanical effect of cryopreservation of decellularized tracheas were also estimated. Results: Two percent SDS was the most effective detergent tested concerning cell removal and preservation of the histological and biomechanical properties of the tracheal wall. However, long-term cryopreservation had no an appreciable effect on the structure, ultrastructure, and biomechanics of decellularized tracheal rings. Conclusion: The results presented here reinforce the use of SDS as a valuable decellularizing agent for porcine tracheas. Furthermore, a cryogenic preservation protocol is described, which has minimal impact on the histological and biomechanical properties of decellularized porcine tracheas.

scholarly journals Short and Long-term Effects of Coronary Thrombolysis in Acute Myocardial Infarction : The treatments for myocardial infarction in acute phase

1993 ◽  
Vol 56 (SupplementV) ◽  
pp. 1409-1413
Author(s):  
Takeshi Motomiya ◽  
Yoshiki Tokuyasu ◽  
Harumizu Sakurada ◽  
Osamu Yanase ◽  
Shuzo Nomura ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Acute Phase ◽  
Long Term Effects ◽  
Coronary Thrombolysis ◽  
Short And Long Term

scholarly journals Extracellular Matrix Turnover Biomarkers Predict Long-Term Left Ventricular Remodeling After Myocardial Infarction

2013 ◽  
Vol 6 (6) ◽  
pp. 1199-1205 ◽  
Author(s):  
Romain Eschalier ◽  
Marie Fertin ◽  
Renaud Fay ◽  
Christophe Bauters ◽  
Faïez Zannad ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Extracellular Matrix ◽  
Ventricular Remodeling ◽  
Left Ventricular Remodeling ◽  
Left Ventricular
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