Super refractory status epilepticus in a patient with Lafora disease treated with vagus nerve stimulation

2019 ◽  
Vol 101 ◽  
pp. 106807
Author(s):  
Francesca Bisulli ◽  
Barbara Mostacci ◽  
Lorenzo Muccioli ◽  
Irene Minardi ◽  
Marco Bandini ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Status Epilepticus ◽  
Lafora Disease ◽  
Refractory Status

Super refractory status epilepticus in Lafora disease interrupted by vagus nerve stimulation: A case report

2019 ◽  
Vol 12 (6) ◽  
pp. 1605-1607 ◽  
Author(s):  
B. Mostacci ◽  
F. Bisulli ◽  
L. Muccioli ◽  
I. Minardi ◽  
M. Bandini ◽  
...  
Keyword(s):  
Case Report ◽  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Status Epilepticus ◽  
Lafora Disease ◽  
Refractory Status

scholarly journals Vagus nerve stimulation in refractory and super-refractory status epilepticus – A systematic review

2019 ◽  
Vol 12 (5) ◽  
pp. 1101-1110 ◽  
Author(s):  
Maxine Dibué-Adjei ◽  
Francesco Brigo ◽  
Takamichi Yamamoto ◽  
Kristl Vonck ◽  
Eugen Trinka
Keyword(s):  
Systematic Review ◽  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Status Epilepticus ◽  
Refractory Status

scholarly journals Vagus Nerve Stimulation (VNS) in Super Refractory New Onset Refractory Status Epilepticus (NORSE)

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Mohankumar Kurukumbi ◽  
James Leiphart ◽  
Anam Asif ◽  
Jing Wang
Keyword(s):  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Epilepsy ◽  
Refractory Status Epilepticus ◽  
Refractory Status ◽  
History Of ◽  
Electrographic Seizures ◽  
New Onset

The treatment protocol of status epilepticus has many associated toxicities so there is interest in alternate nonmedicinal therapies for managing New Onset Refractory Status Epilepticus (NORSE) patients. Vagus nerve stimulation (VNS) is an FDA-approved therapy for refractory epilepsy that has been shown to decrease the frequency and severity of seizures. We present the case of a patient with new-onset refractory status epilepticus (NORSE) whose seizures were successfully treated with vagus nerve stimulation. A 25-year-old male with no history of epilepsy or other neurological disorders presented with altered mental status and generalized tonic-clonic seizures following a two-week history of an upper respiratory tract infection. Lumbar puncture showed neutrophilic pleocytosis, and he was treated for bacterial and viral meningoencephalitis. In spite of treatment, his seizures began increasing in frequency. On day three, the patient entered status epilepticus (SE) refractory to intensive pharmacotherapy with maximal doses of valproate, levetiracetam, and propofol. On day four, SE remained refractory, so pentobarbital was introduced with targeted burst suppression pattern on electroencephalography (EEG). Patient continued to be refractory to these measures, so a vagus nerve stimulator (VNS) was implanted (day eight). Following VNS implantation, EEG demonstrated significant reduction of seizure activity and subsequent magnet swiping continued aborting electrographic seizures. No SE or electrographic seizures were reported for seventy-two hours, but few occasional discharges were reported. Seizures eventually recurred on day fourteen and the patient succumbed to his multiple comorbidities on day seventeen. Due to the efficacy of VNS in refractory epilepsy, there was interest in using it in refractory status epilepticus. Multiple case reports have described a benefit from implantation of VNS in the treatment of SE. The successful use of VNS to acutely terminate status epilepticus for seventy-two hours in this critically ill patient adds to current evidence that there is utility in using VNS for refractory status epilepticus.

Vagus nerve stimulation for refractory status epilepticus

2009 ◽  
Vol 13 (3) ◽  
pp. 286-289 ◽  
Author(s):  
Veerle De Herdt ◽  
Liesbeth Waterschoot ◽  
Kristl Vonck ◽  
Bart Dermaut ◽  
Helene Verhelst ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Status Epilepticus ◽  
Refractory Status

scholarly journals New-onset refractory status epilepticus treated with vagus nerve stimulation: A case report

Seizure ◽  
2017 ◽  
Vol 47 ◽  
pp. 1-4 ◽  
Author(s):  
Tomohiro Yamazoe ◽  
Tohru Okanishi ◽  
Atsushi Yamamoto ◽  
Takehiro Yamada ◽  
Mitsuyo Nishimura ◽  
...  
Keyword(s):  
Case Report ◽  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Status Epilepticus ◽  
Refractory Status ◽  
New Onset

scholarly journals Refractory Status Epilepticus in Genetic Epilepsy—Is Vagus Nerve Stimulation an Option?

2020 ◽  
Vol 11 ◽  
Author(s):  
Nicola Specchio ◽  
Alessandro Ferretti ◽  
Nicola Pietrafusa ◽  
Marina Trivisano ◽  
Costanza Calabrese ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Status Epilepticus ◽  
Genetic Epilepsy ◽  
Refractory Status

Diffusion-weighted imaging and status epilepticus during vagus nerve stimulation

2004 ◽  
Vol 5 (3) ◽  
pp. 411-415 ◽  
Author(s):  
W.O. Tatum IV ◽  
A. Malek ◽  
M. Recio ◽  
J. Orlowski ◽  
R. Murtagh
Keyword(s):  
Status Epilepticus ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Diffusion Weighted Imaging ◽  
Diffusion Weighted
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