Involvement of the nitrergic system in the proconvulsant effect of social isolation stress in male mice

2014 ◽  
Vol 41 ◽  
pp. 158-163 ◽  
Author(s):  
Shayan Amiri ◽  
Armin Shirzadian ◽  
Arya Haj-Mirzaian ◽  
Muhammad Imran-Khan ◽  
Maryam Rahimi Balaei ◽  
...  
Keyword(s):  
Social Isolation ◽  
Male Mice ◽  
Isolation Stress ◽  
Social Isolation Stress

scholarly journals Involvement of the nitrergic system in the proconvulsant effect of social isolation stress in male mice

2018 ◽  
Vol WCP2018 (0) ◽  
pp. PO3-1-25
Author(s):  
Muhammad Imran Khan ◽  
Vahid Nikoui ◽  
Jamal Ahmad ◽  
Bashir Ahmad ◽  
Ahmad-Reza Dehpour
Keyword(s):  
Social Isolation ◽  
Male Mice ◽  
Isolation Stress ◽  
Social Isolation Stress

scholarly journals The possible role of nitric oxide in anti-convulsant effects of Naltrindole in seizure-induced by social isolation stress in male mice

2020 ◽  
Vol 129 ◽  
pp. 110453 ◽  
Author(s):  
Rajan Nikbakhsh ◽  
Rambod Nikbakhsh ◽  
Mahla Radmard ◽  
Armin Tafazolimoghadam ◽  
Arvin Haj-Mirzaian ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Social Isolation ◽  
Male Mice ◽  
Isolation Stress ◽  
Social Isolation Stress

Proconvulsant effect of post-weaning social isolation stress may be associated with dysregulation of opioid system in the male mice

2015 ◽  
Vol 84 (5) ◽  
pp. 445-447 ◽  
Author(s):  
Muhammad Imran Khan ◽  
Armin Shirzadian ◽  
Arya Haj-Mirzaian ◽  
Shahram Ejtemaei Mehr ◽  
Ahmad Reza Dehpour ◽  
...  
Keyword(s):  
Social Isolation ◽  
Opioid System ◽  
Male Mice ◽  
Isolation Stress ◽  
Social Isolation Stress

scholarly journals Social Isolation Stress Induces Anxious-Depressive-Like Behavior and Alterations of Neuroplasticity-Related Genes in Adult Male Mice

2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Alessandro Ieraci ◽  
Alessandra Mallei ◽  
Maurizio Popoli
Keyword(s):  
Prefrontal Cortex ◽  
Social Isolation ◽  
Adult Male ◽  
Adrenal Glands ◽  
Plasma Corticosterone ◽  
Mrna Levels ◽  
Male Mice ◽  
Isolation Stress ◽  
Molecular Changes ◽  
Social Isolation Stress

Stress is a major risk factor in the onset of several neuropsychiatric disorders including anxiety and depression. Although several studies have shown that social isolation stress during postweaning period induces behavioral and brain molecular changes, the effects of social isolation on behavior during adulthood have been less characterized. Aim of this work was to investigate the relationship between the behavioral alterations and brain molecular changes induced by chronic social isolation stress in adult male mice. Plasma corticosterone levels and adrenal glands weight were also analyzed. Socially isolated (SI) mice showed higher locomotor activity, spent less time in the open field center, and displayed higher immobility time in the tail suspension test compared to group-housed (GH) mice. SI mice exhibited reduced plasma corticosterone levels and reduced difference between right and left adrenal glands. SI showed lower mRNA levels of the BDNF-7 splice variant, c-Fos, Arc, and Egr-1 in both hippocampus and prefrontal cortex compared to GH mice. Finally, SI mice exhibited selectively reduced mGluR1 and mGluR2 levels in the prefrontal cortex. Altogether, these results suggest that anxious- and depressive-like behavior induced by social isolation stress correlates with reduction of several neuroplasticity-related genes in the hippocampus and prefrontal cortex of adult male mice.

T1677 Changes in Ghrelin or Upper Gastrointestinal-Associated Factor Gene Expression in Mice That Are Under Social Isolation Stress or Restricted Stress

2009 ◽  
Vol 136 (5) ◽  
pp. A-556
Author(s):  
Hiroshi Takeda ◽  
Shuichi Muto ◽  
Takehiko Katsurada ◽  
Yayoi Inagaki ◽  
Kazuaki Tsuchiya ◽  
...  
Keyword(s):  
Gene Expression ◽  
Social Isolation ◽  
Isolation Stress ◽  
Associated Factor ◽  
Factor Gene ◽  
Social Isolation Stress ◽  
Upper Gastrointestinal
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