Granzyme B-dependent matrix degradation generates anti-angiostatic activity in scleroderma patients

Mary Jo Mulligan-Kehoe; Mary C. Drinane; Livia Casciola-Rosen; Laura K. Hummers; Amy E. Hall; Antony Rosen; Fredrick M. Wigley; Michael Simons

doi:10.1016/j.vph.2006.08.384

Granzyme B-dependent matrix degradation generates anti-angiostatic activity in scleroderma patients

Vascular Pharmacology ◽

10.1016/j.vph.2006.08.384 ◽

2006 ◽

Vol 45 (3) ◽

pp. e147

Author(s):

Mary Jo Mulligan-Kehoe ◽

Mary C. Drinane ◽

Livia Casciola-Rosen ◽

Laura K. Hummers ◽

Amy E. Hall ◽

...

Keyword(s):

Granzyme B ◽

Matrix Degradation ◽

Angiostatic Activity

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Granzyme B‐dependent Matrix Degradation Generates Anti‐Angiostatic Activity in Scleroderma Patients

The FASEB Journal ◽

10.1096/fasebj.20.5.a1099-a ◽

2006 ◽

Vol 20 (5) ◽

Author(s):

Mary Jo Mulligan‐Kehoe ◽

Mary C Drinane ◽

Laura Hummers ◽

Amy E. Hall ◽

Antony Rosen ◽

...

Keyword(s):

Granzyme B ◽

Matrix Degradation ◽

Angiostatic Activity

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Granzyme B contributes to extracellular matrix degradation in UV‐treated skin (1046.1)

The FASEB Journal ◽

10.1096/fasebj.28.1_supplement.1046.1 ◽

2014 ◽

Vol 28 (S1) ◽

Author(s):

Leigh Parkinson ◽

Ana Toro ◽

David Granville

Keyword(s):

Extracellular Matrix ◽

Granzyme B ◽

Matrix Degradation ◽

Extracellular Matrix Degradation

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Benzo(a)pyrene induce the inflammation, nitrosative stress and matrix degradation in articular cartilage

Bone Abstracts ◽

10.1530/boneabs.5.p211 ◽

2016 ◽

Author(s):

Tsung-Hsun Hsieh

Keyword(s):

Articular Cartilage ◽

Nitrosative Stress ◽

Matrix Degradation

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Faculty Opinions recommendation of Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023968.285807 ◽

2005 ◽

Author(s):

Michael L Dustin

Keyword(s):

Granzyme B ◽

Cutting Edge ◽

Regulatory Cells ◽

Edge Contact ◽

Independent Mechanism

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Faculty Opinions recommendation of Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1027289.336049 ◽

2005 ◽

Author(s):

Eckhard Podack

Keyword(s):

T Lymphocytes ◽

Secretory Granule ◽

Cytotoxic T Lymphocytes ◽

Granzyme B ◽

Granule Maturation

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Faculty Opinions recommendation of Human and murine granzyme B exhibit divergent substrate preferences.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1078806.532823 ◽

2007 ◽

Author(s):

Richard L Stevens

Keyword(s):

Granzyme B ◽

Substrate Preferences

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Faculty Opinions recommendation of Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK-p130Cas complex.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13624956.15423062 ◽

2012 ◽

Author(s):

Steven A Rosenzweig

Keyword(s):

Focal Adhesions ◽

Matrix Degradation

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Faculty Opinions recommendation of Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718359874.793494223 ◽

2014 ◽

Author(s):

Florian Kern

Keyword(s):

T Cell ◽

Cytomegalovirus Infection ◽

Granzyme B ◽

Cell Subset ◽

T Cell Subset ◽

Primary Cytomegalovirus Infection

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Faculty Opinions recommendation of ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.738870648.793581298 ◽

2021 ◽

Author(s):

Pamela Stanley

Keyword(s):

Cell Surface ◽

Tumour Cells ◽

Matrix Degradation

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Faculty Opinions recommendation of ER-resident oxidoreductases are glycosylated and trafficked to the cell surface to promote matrix degradation by tumour cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.738870648.793580747 ◽

2020 ◽

Author(s):

Stefan Linder

Keyword(s):

Cell Surface ◽

Tumour Cells ◽

Matrix Degradation

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