Immunomodulatory role of Withania somnifera root powder on experimental induced inflammation: An in vivo and in vitro study

2006 ◽  
Vol 44 (6) ◽  
pp. 406-410 ◽  
Author(s):  
M. Rasool ◽  
P. Varalakshmi
Keyword(s):  
Withania Somnifera ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals In vivo and in vitro study on the role of 3,3'-diindolylmethane in treatment and prevention of nasopharyngeal carcinoma

2013 ◽  
Vol 34 (8) ◽  
pp. 1815-1821 ◽  
Author(s):  
C. Chen ◽  
S.-M. Chen ◽  
B. Xu ◽  
Z. Chen ◽  
F. Wang ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
In Vitro Study ◽  
Vitro Study ◽  
Treatment And Prevention

Role of the Endothelium in the Biotransformation of Sodium Nitroprusside (SNP): In vivo and In vitro Study

2006 ◽  
Vol 30 (S1) ◽  
pp. 191-194 ◽  
Author(s):  
F. Pirrone ◽  
M. Albertini ◽  
S. Mazzola ◽  
M. G. Clement ◽  
G. Aldini ◽  
...  
Keyword(s):  
Sodium Nitroprusside ◽  
In Vitro Study ◽  
Vitro Study

scholarly journals Pancreatic Tumors and Immature Immunosuppressive Myeloid Cells in Blood and Spleen: Role of Inhibitory Co-Stimulatory Molecules PDL1 and CTLA4. An In Vivo and In Vitro Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (1) ◽  
pp. e54824 ◽  
Author(s):  
Daniela Basso ◽  
Paola Fogar ◽  
Massimo Falconi ◽  
Elisa Fadi ◽  
Cosimo Sperti ◽  
...  
Keyword(s):  
Myeloid Cells ◽  
In Vitro Study ◽  
Vitro Study ◽  
Pancreatic Tumors

Cytoprotective and antioxidant role of diallyl tetrasulfide on cadmium induced renal injury: An in vivo and in vitro study

Life Sciences ◽  
2007 ◽  
Vol 80 (7) ◽  
pp. 650-658 ◽  
Author(s):  
L. Pari ◽  
P. Murugavel ◽  
S.L. Sitasawad ◽  
K. Sandeep Kumar
Keyword(s):  
Renal Injury ◽  
In Vitro Study ◽  
Vitro Study

THU0194 Role of Platelets in the Pathogenesis of Osteoarthritis and Biological Effects of Hyaluronic Acid: in Vivo and in Vitro Study

2014 ◽  
Vol 73 (Suppl 2) ◽  
pp. 248.3-249
Author(s):  
A. Alunno ◽  
E. Petito ◽  
G. Mirabelli ◽  
E. Falcinelli ◽  
F. Luccioli ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Biological Effects ◽  
In Vitro Study ◽  
Vitro Study

Thrombin Generation by Fetoscopic Trauma to the Fetal Membranes: An in vivo and in vitro Study

2015 ◽  
Vol 39 (4) ◽  
pp. 261-268 ◽  
Author(s):  
Alexander C. Engels ◽  
Dries Bauters ◽  
Rita Rynkevic ◽  
Savitree Pranpanus ◽  
Jute Richter ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Thrombin Generation ◽  
In Vitro Study ◽  
Vitro Study ◽  
Thrombin Inhibitor ◽  
Thrombin Receptor ◽  
Fetal Membranes

Objective: We first aimed to investigate in vivo thrombin generation induced by fetoscopy, and second we used term membrane explants for measurement of thrombin generation, thrombin receptor location and induction of selected matrix metalloproteinases (MMPs) in tissue culture. Materials and Methods: In vivo study (37 cases): samples of amniotic fluid were taken at the beginning and end of fetoscopy (mean gestational age 26.7 weeks) and analyzed by ELISA for thrombin-antithrombin complexes. In vitro study: fetal membranes were put in culture and punctured for measurement of thrombin generation by calibrated automated thrombography and ELISA. Induction of MMP-9 and MMP-2 was analyzed by zymography. PAR-1 was localized by immunohistochemistry. Results: No significant increase in thrombin-antithrombin was measured in amniotic fluid obtained during fetoscopy. In vitro, thrombin generation induced by needle trauma of membrane cultures is correlated to the amount of plasma. Activity of MMP-9 but not MMP-2 was elevated in cultured membranes but could not be inhibited by a thrombin inhibitor. On histology, the thrombin receptor PAR-1 was located in the chorion and decidua, but not in the amnion. Discussion: Despite the influence of thrombin on punctured fetal membranes in vitro, the role of thrombin in iatrogenic preterm premature rupture of membranes is questionable.

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