scholarly journals Global gene expression analysis of two Streptococcus thermophilus bacteriophages using DNA microarray

Virology ◽  
2005 ◽  
Vol 340 (2) ◽  
pp. 192-208 ◽  
Author(s):  
Martin Duplessis ◽  
W. Michael Russell ◽  
Dennis A. Romero ◽  
Sylvain Moineau
Keyword(s):  
Gene Expression ◽  
Dna Microarray ◽  
Expression Analysis ◽  
Gene Expression Analysis ◽  
Streptococcus Thermophilus ◽  
Global Gene Expression ◽  
Global Gene Expression Analysis

scholarly journals Global Gene Expression Analysis of the Brainstem in EV71- and CVA16-Infected Gerbils

Viruses ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 46 ◽  
Author(s):  
Yi-Sheng Sun ◽  
Zhang-Nv Yang ◽  
Fang Xu ◽  
Chen Chen ◽  
Hang-Jing Lu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Expression Analysis ◽  
Gene Expression Analysis ◽  
Enterovirus 71 ◽  
Foot And Mouth Disease ◽  
Global Gene Expression ◽  
Solid Foundation ◽  
Differential Gene ◽  
Global Gene Expression Analysis ◽  
Upregulated Genes

Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the two most important pathogens of hand, foot, and mouth disease (HFMD). However, the neuropathogenesis of EV71 and CVA16 has not been elucidated. In our previous study, we established gerbils as a useful model for both EV71 and CVA16 infection. In this work, we used RNA-seq technology to analyze the global gene expression of the brainstem of EV71- and CVA16-infected gerbils. We found that 3434 genes were upregulated while 916 genes were downregulated in EV71-infected gerbils. In CVA16-infected gerbils, 1039 genes were upregulated, and 299 genes were downregulated. We also found significant dysregulation of cytokines, such as IP-10 and CXCL9, in the brainstem of gerbils. The expression levels of 10 of the most upregulated genes were confirmed by real-time RT-PCR, and the upregulated tendency of most genes was in accordance with the differential gene expression (DGE) results. Our work provided global gene expression analysis of virus-infected gerbils and laid a solid foundation for elucidating the neuropathogenesis mechanisms of EV71 and CVA16.

Global Gene Expression Analysis of Long and Short Day 15 Bovine Conceptuses Produced In Vivo.

2012 ◽  
Vol 87 (Suppl_1) ◽  
pp. 192-192
Author(s):  
Callie V. Barnwell ◽  
Christopher M. Ashwell ◽  
Peter W. Farin ◽  
William T. Farmer ◽  
Charlotte E. Farin
Keyword(s):  
Gene Expression ◽  
Expression Analysis ◽  
Gene Expression Analysis ◽  
Global Gene Expression ◽  
Short Day ◽  
Global Gene Expression Analysis
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