Ventilation distribution assessed with electrical impedance tomography and the influence of tidal volume, recruitment and positive end-expiratory pressure in isoflurane-anesthetized dogs

2017 ◽  
Vol 44 (2) ◽  
pp. 254-263
Author(s):  
Aline M. Ambrosio ◽  
Tatiana P.A. Carvalho-Kamakura ◽  
Keila K. Ida ◽  
Barbara Varela ◽  
Felipe S.R.M. Andrade ◽  
...  
Keyword(s):  
Tidal Volume ◽  
Electrical Impedance Tomography ◽  
Electrical Impedance ◽  
Positive End Expiratory Pressure ◽  
Ventilation Distribution ◽  
Impedance Tomography ◽  
Anesthetized Dogs

scholarly journals Regional lung response to bronchodilator reversibility testing determined by electrical impedance tomography in chronic obstructive pulmonary disease

2016 ◽  
Vol 311 (1) ◽  
pp. L8-L19 ◽  
Author(s):  
Barbara Vogt ◽  
Zhanqi Zhao ◽  
Peter Zabel ◽  
Norbert Weiler ◽  
Inéz Frerichs
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Tidal Volume ◽  
Pulmonary Disease ◽  
Electrical Impedance Tomography ◽  
Electrical Impedance ◽  
Chronic Obstructive ◽  
Ventilation Distribution ◽  
Prognostic Information ◽  
Impedance Tomography ◽  
Obstructive Pulmonary Disease

Patients with obstructive lung diseases commonly undergo bronchodilator reversibility testing during examination of their pulmonary function by spirometry. A positive response is defined by an increase in forced expiratory volume in 1 s (FEV1). FEV1 is a rather nonspecific criterion not allowing the regional effects of bronchodilator to be assessed. We employed the imaging technique of electrical impedance tomography (EIT) to visualize the spatial and temporal ventilation distribution in 35 patients with chronic obstructive pulmonary disease at baseline and 5, 10, and 20 min after bronchodilator inhalation. EIT scanning was performed during tidal breathing and forced full expiration maneuver in parallel with spirometry. Ventilation distribution was determined by EIT by calculating the image pixel values of FEV1, forced vital capacity (FVC), tidal volume, peak flow, and mean forced expiratory flow between 25 and 75% of FVC. The global inhomogeneity indexes of each measure and histograms of pixel FEV1/FVC values were then determined to assess the bronchodilator effect on spatial ventilation distribution. Temporal ventilation distribution was analyzed from pixel values of times needed to exhale 75 and 90% of pixel FVC. Based on spirometric FEV1, significant bronchodilator response was found in 17 patients. These patients exhibited higher postbronchodilator values of all regional EIT-derived lung function measures in contrast to nonresponders. Ventilation distribution was inhomogeneous in both groups. Significant improvements were noted for spatial distribution of pixel FEV1 and tidal volume and temporal distribution in responders. By providing regional data, EIT might increase the diagnostic and prognostic information derived from reversibility testing.

Regional ventilation distribution determined by electrical impedance tomography: Reproducibility and effects of posture and chest plane

Respirology ◽  
2011 ◽  
Vol 16 (3) ◽  
pp. 523-531 ◽  
Author(s):  
FLORIAN REIFFERSCHEID ◽  
GUNNAR ELKE ◽  
SVEN PULLETZ ◽  
BARBARA GAWELCZYK ◽  
INGMAR LAUTENSCHLÄGER ◽  
...  
Keyword(s):  
Electrical Impedance Tomography ◽  
Electrical Impedance ◽  
Ventilation Distribution ◽  
Regional Ventilation ◽  
Impedance Tomography
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