Meta-analysis of the effect of MDR1 C3435 polymorphism on tacrolimus pharmacokinetics in renal transplant recipients

2012 ◽  
Vol 27 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Yi Li ◽  
Xin Hu ◽  
Bei Cai ◽  
Jie Chen ◽  
Yangjuan Bai ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Meta Analysis ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Tacrolimus Pharmacokinetics

scholarly journals Prevalence of BK Virus among Iranian Renal Transplant Recipients: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 4 (4) ◽  
pp. 50-61
Author(s):  
Mohsen Ebrahimi ◽  
Alireza Mohebbi ◽  
Mohammad Mostakhdem Hashemi ◽  
Mobina Ashrafi Shahmirzadi ◽  
◽  
...  
Keyword(s):  
Systematic Review ◽  
Renal Transplant ◽  
Meta Analysis ◽  
Bk Virus ◽  
Renal Transplant Recipients ◽  
Transplant Recipients

Cyp3A4, Cyp3A5, and MDR-1 genetic influences on tacrolimus pharmacokinetics in renal transplant recipients

2006 ◽  
Vol 16 (9) ◽  
pp. 659-665 ◽  
Author(s):  
Jean Nicholas Roy ◽  
Azemi Barama ◽  
Charles Poirier ◽  
Bernard Vinet ◽  
Michel Roger
Keyword(s):  
Renal Transplant ◽  
Genetic Influences ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Tacrolimus Pharmacokinetics ◽  
Mdr 1

Rimonabant Affects Cyclosporine A, but Not Tacrolimus Pharmacokinetics in Renal Transplant Recipients

2009 ◽  
Vol 87 (8) ◽  
pp. 1221-1224 ◽  
Author(s):  
Rune Amundsen ◽  
Anders Åsberg ◽  
Ida Robertsen ◽  
Nils T. Vethe ◽  
Stein Bergan ◽  
...  
Keyword(s):  
Renal Transplant ◽  
Cyclosporine A ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Tacrolimus Pharmacokinetics

scholarly journals Evaluation of Serum Interleukin-6 Levels in the Renal Transplant Recipients: A Systematic Review and Meta-Analysis of Case-Control Studies

2019 ◽  
Vol 7 (1) ◽  
pp. 174-178 ◽  
Author(s):  
Hamidreza Omrani ◽  
Sayed Vahid Jasemi ◽  
Masoud Sadeghi ◽  
Sima Golmohamadi
Keyword(s):  
Renal Transplant ◽  
Meta Analysis ◽  
Elevated Serum ◽  
Cochrane Library ◽  
P Value ◽  
Renal Transplant Recipients ◽  
Healthy Controls ◽  
Transplant Recipients ◽  
Case Control Studies ◽  
Meta Regression Analysis

AIM: The purpose of this meta-analysis was the assessment of the serum IL-6 levels in the renal transplant recipients compared to the healthy controls. MATERIAL AND METHODS: Four databases including PubMed, Web of Science, Scopus, and Cochrane Library were searched up to July 2018 without language restriction. The quality of studies was evaluated using the Newcastle-Ottawa scale (NOS). A continuous random-effects meta-analysis was used by RevMan 5.3 using the mean difference (MD) and 95% confidence intervals (CIs). Also, a regression model was done by Comprehensive Meta-Analysis version 2 (CMA v2). RESULTS: Out of 615 studies identified in the databases, 15 studies included and analysed in the meta-analysis. The studies were reported from 1994 to 2018. The meta-analysis included 1035 renal transplant recipients and 682 healthy controls. The pooled MD of the serum IL-6 levels in the transplant recipients compared to the healthy controls was 3.25 pg/mL [95%CI: 2.17, 4.32; P < 0.00001; I2 = 98% (P < 0.00001)]. Meta-regression analysis showed that one of the reasons of heterogeneity is the year of publication (Correlation coefficient (r) = 0.208, p-value = 0.00002). CONCLUSION: An elevated serum IL-6 level in the renal transplant recipients compared to the healthy controls showed that the serum level of this marker could be used for the evaluation of inflammation in ESRD patients undergoing renal transplantation.

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