Risk of adverse post-transplant events after kidney allograft transplantation as predicted by CTLA-4 +49 and TNF-α −308 single nucleotide polymorphisms: A preliminary study

2006 ◽  
Vol 16 (3-4) ◽  
pp. 194-199 ◽  
Author(s):  
Ketevan Gendzekhadze ◽  
Pedro Rivas-Vetencourt ◽  
Ramón F. Montano
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Kidney Allograft ◽  
Post Transplant ◽  
Allograft Transplantation ◽  
Tnf Α ◽  
Preliminary Study

A proposed HLA-B*27 screening method for ankylosing spondylitis detection based on tag-single nucleotide polymorphisms: a preliminary study

2021 ◽  
Author(s):  
Gabriela Angélica Martínez-Nava ◽  
Yessica Zamudio-Cuevas ◽  
Ninoska Aleida Terrazas-Ontiveros ◽  
Karina Martínez-Flores ◽  
Rolando Espinosa-Morales ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Single Nucleotide Polymorphisms ◽  
Screening Method ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Preliminary Study

The influence of CTLA-4 single nucleotide polymorphisms on acute kidney allograft rejection in Turkish patients

2015 ◽  
Vol 29 (7) ◽  
pp. 612-618 ◽  
Author(s):  
Çağlar Ruhi ◽  
Nilgün Sallakçi ◽  
Olcay Yeğin ◽  
Gültekin Süleymanlar ◽  
F. Fevzi Ersoy
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Allograft Rejection ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Kidney Allograft ◽  
Turkish Patients ◽  
Kidney Allograft Rejection

Single nucleotide polymorphisms of TNF-Α gene in febrile seizures

2015 ◽  
Vol 356 (1-2) ◽  
pp. 153-156 ◽  
Author(s):  
Ameneh Zare-Shahabadi ◽  
Mahmoud Reza Ashrafi ◽  
Amin Shahrokhi ◽  
Samaneh Soltani ◽  
Samaneh Zoghi ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Febrile Seizures ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Tnf Α

TNF-α promoter single nucleotide polymorphisms are markers of human ancestry

2002 ◽  
Vol 3 (8) ◽  
pp. 482-487 ◽  
Author(s):  
A Baena ◽  
J Y Leung ◽  
A D Sullivan ◽  
I Landires ◽  
N Vasquez-Luna ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Tnf Α ◽  
Human Ancestry

scholarly journals TNF-α, IL-4Rα AND IL-4 Polymorphisms in Mild to Severe Asthma from Italian Caucasians

2013 ◽  
Vol 26 (1) ◽  
pp. 75-84 ◽  
Author(s):  
F.L.M. Ricciardolo ◽  
V. Sorbello ◽  
M. Silvestri ◽  
M. Giacomelli ◽  
V.M.G. Debenedetti ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Protein Coding ◽  
Cytokine Genes ◽  
Asthmatic Patients ◽  
Tnf Α ◽  
Snp Mapping ◽  
Polymerase Chain ◽  
First Time

Asthma is a chronic airway inflammatory disease associated with airway hyperresponsiveness which affects subjects with genetic predisposition. An association has been reported between some polymorphisms in various cytokine genes and asthma. Most of them are single nucleotide polymorphisms (SNPs). These polymorphisms are detected in the protein coding sequence or in the promoter region thus influencing cytokine production. We investigated the involvement of SNP mapping in 5 cytokine genes in mild to severe asthmatics of Italian Caucasians. The frequency of alleles and genotypes, relatively to 10 allelic specificities of the cytokine genes, was defined in 57 asthmatics and in 124 control subjects by a Polymerase Chain Reaction-Sequence Specific Primer method. TNF-α -308A and TNF-α -238A allele frequencies were higher in asthmatics than in controls (p<0.001). Significant differences in the frequency of IL-4 -590T allele and of IL-4Rα + 1902A allele were also detected in asthmatics in comparison with controls (p<0.001 and p=0.005, respectively). Similarly, IL-1α -889C allele was present in 84.1% of asthmatics and in 70.2% of controls (p=0.013). Furthermore, the IL-4Rα + 1902A/A and IL-1α -889C/C homozygous conditions and the TNF-α -308G/A, TNF-α -238G/A, IL-4 -590T/C and IL-10 -1082G/A heterozygous conditions were significantly associated with asthma (p<0.05). ACA haplotype of IL-10 was observed only in asthmatic patients. This study reports, for the first time, the frequency of 10 different single nucleotide polymorphisms in 5 cytokine genes in the Italian Caucasians. Furthermore, we also indicate that in our population some single nucleotide polymorphisms are associated with mild to severe bronchial asthma.

TNF-α (−308G>A) and TNF-R1 (36A>G) single nucleotide polymorphisms are strong risk factors for odontogenic keratocystic tumor development

2017 ◽  
Vol 46 (4) ◽  
pp. 292-296 ◽  
Author(s):  
Branislav Ilic ◽  
Nadja Nikolic ◽  
Miroslav Andric ◽  
Drago Jelovac ◽  
Biljana Milicic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Single Nucleotide Polymorphisms ◽  
Tumor Development ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Tnf Α
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