What does Drosophila genetics tell us about speciation?

2006 ◽  
Vol 21 (7) ◽  
pp. 386-393 ◽  
Author(s):  
James Mallet
Keyword(s):  
Drosophila Genetics

Lords of the Fly: Drosophila Genetics and the Experimental Life.

1995 ◽  
Vol 24 (2) ◽  
pp. 264
Author(s):  
Andrew Pickering ◽  
Robert E. Kohler
Keyword(s):  
Drosophila Genetics

Simulating Drosophila Genetics with the Computer

1979 ◽  
Vol 41 (4) ◽  
pp. 219-225
Author(s):  
James W. Small, ◽  
Kathryn L. Edwards
Keyword(s):  
Drosophila Genetics

Drosophila genetics: Patterns of differentiation

Nature ◽  
1985 ◽  
Vol 317 (6034) ◽  
pp. 202-203
Author(s):  
P. W. Ingham
Keyword(s):  
Drosophila Genetics

scholarly journals Dual proteomics of Drosophila melanogaster hemolymph infected with the heritable endosymbiont Spiroplasma poulsonii

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250524
Author(s):  
Florent Masson ◽  
Samuel Rommelaere ◽  
Alice Marra ◽  
Fanny Schüpfer ◽  
Bruno Lemaitre
Keyword(s):  
Drosophila Melanogaster ◽  
Tissue Distribution ◽  
Drosophila Genetics ◽  
Transcriptomics Data ◽  
Bacterial Endosymbionts ◽  
Chronic Activation ◽  
Immune Pathway ◽  
Proteome Changes ◽  
The Impact ◽  
Species Being

Insects are frequently infected with heritable bacterial endosymbionts. Endosymbionts have a dramatic impact on their host physiology and evolution. Their tissue distribution is variable with some species being housed intracellularly, some extracellularly and some having a mixed lifestyle. The impact of extracellular endosymbionts on the biofluids they colonize (e.g. insect hemolymph) is however difficult to appreciate because biofluid composition can depend on the contribution of numerous tissues. Here we investigate Drosophila hemolymph proteome changes in response to the infection with the endosymbiont Spiroplasma poulsonii. S. poulsonii inhabits the fly hemolymph and gets vertically transmitted over generations by hijacking the oogenesis in females. Using dual proteomics on infected hemolymph, we uncovered a weak, chronic activation of the Toll immune pathway by S. poulsonii that was previously undetected by transcriptomics-based approaches. Using Drosophila genetics, we also identified candidate proteins putatively involved in controlling S. poulsonii growth. Last, we also provide a deep proteome of S. poulsonii, which, in combination with previously published transcriptomics data, improves our understanding of the post-transcriptional regulations operating in this bacterium.

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