Introduction:
A fundamental gap in correlation appears to exist between bystander Cardiopulmonary Resuscitation (CPR) and preservation of the gift of life for people who die each day awaiting organ transplantation. As a result, the incidence of bystander CPR as a bridge to organ donation has not been articulated. Hypothesis: We assessed the hypothesis that kidneys recovered with bystander CPR demonstrate equivalent survival rates with first responder CPR and or no CPR.
Methods:
We retrospectively analyzed our transplant database from 2008-2013. We also evaluated the nationwide, population-based database from the United Network for Organ Sharing.
Results:
A total of 643 deceased donors were utilized to sustain life in a sample size of 882 kidney transplant recipients at our center. There were 77 bystander CPR - mean age 49.8 (SEM 1.75), 192 first responder CPR - mean age 52.45 (SEM 1.05), and 613 no CPR - mean age 52.58 (SEM 0.63). The mean length of stay days were 9.42 (SEM 0.64) bystander CPR, 9.03 (SEM 0.51) first responder CPR, and 10.73 (SEM 0.49) no CPR. The mean one year graft survival rate was 97.4% (SEM 0.01, CI 94.85-99.94) bystander CPR, 93.8% (SEM 0.02, CI 90.46-97.03) first responder CPR and 94.1% (SEM 0.01, CI 92.33-95.86). The mean death-censored graft survival days were 2230 (SEM 67.98) bystander CPR, 2351.22 (SEM 38.02) first responder CPR, and 2292.41 (SEM 26.32) no CPR; with a Log rank p-value=0.338. The United States’ data demonstrated 133,369 deceased donors with 44,469 receiving CPR (33.34%). The mean graft survival rate at one year was 92.62% (CI 92.18-93.06) with CPR and 91.54 % (CI 91.21-91.88) no CPR. No distinctions were made regarding the type of CPR in the national database. Conclusions: Bystander CPR saves lives both with the primary return to baseline function and the secondary gain of the gift of life. Intentional effort should be devoted to tracking the results of bystander CPR and the parallel consequence of organ donation.
Potential of organ donation from deceased donors: study from a public sector hospital in India