Retroperitoneal Pancreas Transplantation With the Use of Duodenal Drainage via “Button Technique”: First Clinical Practice (Case Report)

2017 ◽  
Vol 49 (10) ◽  
pp. 2347-2351
Author(s):  
A. Pinchuk ◽  
I. Dmitriev ◽  
K. Lazareva ◽  
R. Storozhev ◽  
A. Balkarov ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Pancreas Transplantation ◽  
Duodenal Drainage

Case report: a child with cystic fibrosis and phenylketonuria

2020 ◽  
Vol 1 (2) ◽  
pp. 38-44
Author(s):  
Irina V. Vakhlova ◽  
Anastasia D. Kazachina ◽  
Olga A. Beglyanina
Keyword(s):  
Cystic Fibrosis ◽  
Case Report ◽  
Clinical Practice ◽  
Neonatal Screening ◽  
Genetic Disorders ◽  
Epileptiform Activity ◽  
Autism Spectrum ◽  
Speech Development ◽  
Inherited Disorders ◽  
Congenital Diseases

Background. In the international clinical practice there have been occasional reports of phenylketonuria (PKU) and cystic fibrosis (CF) found simultaneously in the same patient. Both PKU and CF are the inherited disorders characterized by autosomal recessive type of inheritance. Currently the combination of two or more inherited disorders in one patient is considered to be a clinical rarity.Case description. This is a clinical case of two genetic disorders, CF and PKU, combined in a 5-year old patient who had been followed up since birth. Owing to implementation of neonatal screening for inherited and congenital diseases into clinical practice, during the first month of life the infant was diagnosed with CF (diagnostically significant elevation of immunoreactive trypsin [IRT] at the initial [163.2 ng/mL] and repeat testing on day 21 of life [138.7 ng/mL]) and PKU (phenylalanine [PA] level 15.9 mg/dL). Both disorders have been confirmed by genetic tests, i.e., homozygous DelF508 mutation was found in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and P281L mutation in the phenylalanine hydroxylase (PAH) gene was also present in homozygous state. Child’s parents strictly adhered to dietary and treatment recommendations. By the age of 5 years the child developed symptoms of neurological disorder and disorder of the respiratory system, cognitive impairment and delay in speech development, subclinical epileptiform activity with high risk of epilepsy, and chronic inflammation of the respiratory tract.Conclusion. This case report demonstrates the important role of neonatal screening in early diagnosis and timely start of therapy, and underscores the importance of continuous medication in such genetic disorders as CF and PKU. On the whole, such approach brings about a relative preservation of functioning of the most affected organs and systems. By the age of 5 years the child does not form bronchiectases, shows no signs of chronic hypoxia, nutritional deficiency or pronounced neurologic deficit, and is at low risk for the development of autism spectrum disorder. At the same time, the larger scale and longer-term observations are required in order to make the unequivocal conclusions about the prognosis of these diseases under conditions of modern-day medical follow-up.

scholarly journals Case report of von willebrand disease after tonsillotomy and adenotomy in a child

2021 ◽  
Vol 20 (1) ◽  
pp. 89-92
Author(s):  
S. S. Makhmudov ◽  
◽  
A. A. Ochilzoda ◽  
F. P. Dzhamolov ◽  
A. Z. Mutalibov ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Surgical Treatment ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
Von Willebrand Disease ◽  
Rare Occurrence ◽  
Von Willebrand

The authors present a clinical case of von Willebrand disease detected after tonsillotomy and adenotomy in a child. The peculiarity of this observation lies in the rare occurrence of von Willebrand disease in clinical practice, as well as the manifestation of the clinical manifestations of this pathology against the background of surgical treatment in a child.

scholarly journals Fixed-dose combination of ivabradine and metoprolol in a patient with stable coronary artery disease: a case report

2021 ◽  
Vol 26 (9) ◽  
pp. 4657
Author(s):  
A. M. Shimkevich
Keyword(s):  
Coronary Artery Disease ◽  
Case Report ◽  
Clinical Practice ◽  
Coronary Artery ◽  
Stable Coronary Artery Disease ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Actual Clinical Practice ◽  
Dose Combination ◽  
Artery Disease

This article discusses a case of using fixed-dose combination of ivabradine/metoprolol in actual clinical practice.

scholarly journals Improvement in refractory psychosis after initiating management for underlying ADHD

2015 ◽  
Vol 84 (S1) ◽  
pp. 6-8
Author(s):  
Michael Blaszak ◽  
Danica Brister ◽  
Jordon Charlebois ◽  
Erica Hoe ◽  
Maggie Siu
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Case Report ◽  
Clinical Practice ◽  
Attention Deficit ◽  
Clinical Case ◽  
Psychotic Symptoms ◽  
Visual Hallucinations ◽  
Hyperactivity Disorder ◽  
Stimulant Medications ◽  
Pathophysiologic Mechanisms

We report on a unique clinical case of psychosis precipitated by Attention Deficit Hyperactivity Disorder (ADHD) and explore its implications for clinical practice as well as our understanding of these conditions. We describe a clinical case of a 46-year-old male presenting with auditory, olfactory, tactile, and visual hallucinations. We reviewed the literature on reported cases in which psychotic symptoms were treated with stimulant medications for ADHD comorbidity. This case report reveals the potential for properly selected patients to benefit from a consideration of ADHD comorbidity and a trial of treatment with that focus. In addition, the literature reveals a pathophysiologic association between psychosis and ADHD supported by neurobiological data. However, far more research is required to fully understand these conditions and their relationship. We conclude that ADHD and psychosis have some related pathophysiologic mechanisms but their connection has not been adequately explored. This case adds support to literature suggesting that in refractory psychosis, clinicians should re-evaluate the diagnosis and one of the considerations should be ADHD. In certain cases, the presence of psychotic symptoms with ADHD should not exclude the use of stimulants.

scholarly journals Bortezomib maintenance for the treatment of Monoclonal Gammopathy of Renal Significance

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Holly Lee ◽  
Peter Duggan ◽  
Ernesta Paola Neri ◽  
Jason Tay ◽  
Victor Jimenez Zepeda
Keyword(s):  
Multiple Myeloma ◽  
Case Report ◽  
Clinical Practice ◽  
B Cells ◽  
Renal Disease ◽  
Maintenance Therapy ◽  
Membranoproliferative Glomerulonephritis ◽  
Monoclonal Gammopathy ◽  
Renal Survival ◽  
Monoclonal Proteins

Monoclonal gammopathy of renal significance (MGRS) defines renal disease resulting from monoclonal proteins that are secreted from clonal B cells, that does not meet criteria for lymphoma or multiple myeloma. Recognizing MGRS in clinical practice is important because renal outcomes are poor and treatments targeting the underlying clonal disease have been associated with improved renal survival. In this case report, we present a case of a patient with membranoproliferative glomerulonephritis (MPGN) with IgG-kappa deposition who underwent clone directed treatment in a phased approach with induction and maintenance to achieve renal response. This is one of the first cases to report on MGRS treatment that required extended maintenance therapy.

scholarly journals Occipitalization of atlas - a case report

2016 ◽  
Vol 05 (02) ◽  
pp. 107-109
Author(s):  
Saranya Deb Barma ◽  
Gunamani Rabba ◽  
Kunjalal Talukdar
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Clinical Practice ◽  
Undergraduate Students ◽  
Neurological Complications ◽  
Occipital Bone ◽  
Clinical Implications ◽  
Short Neck ◽  
Neck Movement ◽  
Orthopaedic Surgeons

AbstractThe atlas vertebra articulates with the occipital bone of the skull by a pair of sunovial joints. Occipitalization is a congenital fusion of the atlas to the base of the occiput which reduces the foramen mangnum dimension leading to neurological complications due to compression of spinal cord. Individuals with occipitalization of the atlas may have low hairline, torticollis, restricted neck movement and abnormal short neck. During routine osteology demonstration class for undergraduate students, a total atlanto-occipital fusion was seen. The clinical implications of altanto-occipitalization may be beneficial for neurosurgeons, neurologists, orthopaedic surgeons and radiologists in day-to-day clinical practice.

scholarly journals Eosinophilic Meningitis and Intracranial Haemorrhage: Can it be Neuro-Gnathostomiasis?

2019 ◽  
Vol 38 (2) ◽  
pp. 125-127
Author(s):  
Srijana Basnet ◽  
Laxman Shrestha ◽  
Daman Raj Poudel
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Intracranial Haemorrhage ◽  
Hemorrhagic Stroke ◽  
Etiologic Agent ◽  
Eosinophilic Meningitis ◽  
Peripheral Eosinophilia

Peripheral eosinophilia is commonly encountered in our clinical practice. In this case report, we present a child who presented with hemorrhagic stroke and was finally diagnosed of eosinophilic meningitis. In this case report, we also propose probable etiologic agent.

Delirium on clozapine: A tale of friend turned foe-A case report

2020 ◽  
pp. 009121742097282 ◽  
Author(s):  
Aparna Das ◽  
Rebecca Minner ◽  
Lewis Krain ◽  
John Spollen
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Side Effects ◽  
Adverse Effects ◽  
Older Adult ◽  
Psychiatric Illness ◽  
Management Strategies ◽  
Treatment Resistant ◽  
Drug Of Choice ◽  
Life Threatening

Treatment resistant schizophrenia (TRS) is often encountered in clinical practice. Clozapine remains the drug of choice in the management of TRS. Several studies have shown that clozapine is the most effective antipsychotic medication to date for TRS. But it is also well known that it has multiple side effects. Some side effects are transient and relatively benign, while other adverse effects are menacing, serious and life-threatening. Delirium may occur with clozapine and is a therapeutic challenge as there is always a risk of precipitating delirium on clozapine rechallenge. Limited management strategies are available as alternatives for the management of psychiatric illness stabilized on clozapine. In this case report, we describe an older adult patient who developed delirium on clozapine. The aims of this case report are to discuss the mechanism by which clozapine leads to delirium, revisit various factors which could possibly lead to delirium, and discuss the different management strategies available for management of psychiatric illness for a patient previously stabilized on clozapine.

Endovascular Management of Mycotic Pseudoaneurysm After Pancreas Transplantation: Case Report and Literature Review

2020 ◽  
Vol 52 (2) ◽  
pp. 660-666
Author(s):  
Jinna Yao ◽  
Mauro Vicaretti ◽  
Taina Lee ◽  
Rajith Amaratunga ◽  
Nicholas Cocco ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Pancreas Transplantation ◽  
Endovascular Management ◽  
Mycotic Pseudoaneurysm
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