Temporal Trend and Time-Varying Effect of Preemptive Second Kidney Transplantation on Graft Survival: A 30-Year Single-Center Cohort Study

2016 ◽  
Vol 48 (8) ◽  
pp. 2663-2668 ◽  
Author(s):  
S. Girerd ◽  
N. Girerd ◽  
A. Aarnink ◽  
E. Solimando ◽  
M. Ladrière ◽  
...  
2017 ◽  
Vol 49 (5) ◽  
pp. 1068-1072 ◽  
Author(s):  
Y. Itabashi ◽  
Y. Ohashi ◽  
M. Muramatsu ◽  
T. Kawamura ◽  
Y. Hyodo ◽  
...  

Author(s):  
Clarisse Grèze ◽  
Bruno Pereira ◽  
Yves Boirie ◽  
Laurent Guy ◽  
Clémentine Millet ◽  
...  

Abstract Background The access of obese patients to kidney transplantation is limited despite several studies showing that obese transplant recipients had a better survival rate than those undergoing dialysis. The aim of this study was to compare patient and graft survival rates and post-renal transplant complications in obese patients and non-obese patients and to assess the effect of pre-transplant weight loss in obese patients on transplant outcomes. Methods We carried out a prospective cohort study using two French registries REIN and CRISTAL on 7 270 kidney transplant patients between 2008 and 2014 in France. We compared obese patients with non-obese patients and obese patients who lost more than 10% of weight before the transplant (Obese WL and Obese nWL). Results The mean BMI in our obese patients was 32 kg/m2. Graft survival was lower in obese patients than in non-obese patients (HR = 1.40, IC 95% [1.09; 1.78], P = 0.007) whereas patient survival was similar (HR = 0.94, IC 95% [0.73; 1.23], P = 0.66). Graft survival was significantly lower in Obese WL than in Obese nWL (HR = 2.17, CI 95% [1.02; 4.63], P = 0.045) whereas patient survival was similar in the two groups (HR = 0.79, IC 95% [0.35; 1.77], P = 0.56). Conclusion Grade I obesity does not seem to be a risk factor for excess mortality after kidney transplantation and should not be an obstacle to having access to a graft. Weight loss before a kidney transplant in this patients should not be essential for registration on waiting list.


2010 ◽  
Vol 90 ◽  
pp. 721
Author(s):  
K. H. Huh ◽  
Y. S. Kim ◽  
D. J. Joo ◽  
M. K. Ju ◽  
M. S. Kim ◽  
...  

2017 ◽  
Vol 31 (4) ◽  
pp. 408-423 ◽  
Author(s):  
Sophie Girerd ◽  
Nicolas Girerd ◽  
Kevin Duarte ◽  
Magali Giral ◽  
Christophe Legendre ◽  
...  

2014 ◽  
Vol 97 (9) ◽  
pp. 934-939 ◽  
Author(s):  
Vincenzo Losappio ◽  
Giovanni Stallone ◽  
Barbara Infante ◽  
Antonio Schena ◽  
Michele Rossini ◽  
...  

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