Risk Factors of Pancreatic Graft Loss and Death of Receptor After Simultaneous Pancreas/Kidney Transplantation

2014 ◽  
Vol 46 (6) ◽  
pp. 1827-1835 ◽  
Author(s):  
M.G. Sousa ◽  
M.M. Linhares ◽  
A.A. Salzedas-Netto ◽  
A.M. Gonzalez ◽  
E.B. Rangel ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Transplantation ◽  
Graft Loss ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Simultaneous Pancreas Kidney Transplantation ◽  
Pancreatic Graft

scholarly journals Impact of Early Pancreatic Graft Loss on Outcome after Simultaneous Pancreas–Kidney Transplantation (SPKT)—A Landmark Analysis

2021 ◽  
Vol 10 (15) ◽  
pp. 3237
Author(s):  
Lukas Johannes Lehner ◽  
Robert Öllinger ◽  
Brigitta Globke ◽  
Marcel G. Naik ◽  
Klemens Budde ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Graft Survival ◽  
Graft Loss ◽  
Type I ◽  
Kidney Graft ◽  
Landmark Analysis ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Simultaneous Pancreas Kidney Transplantation ◽  
Pancreas Graft

(1) Background: Simultaneous pancreas–kidney transplantation (SPKT) is a standard therapeutic option for patients with diabetes mellitus type I and kidney failure. Early pancreas allograft failure is a complication potentially associated with worse outcomes. (2) Methods: We performed a landmark analysis to assess the impact of early pancreas graft loss within 3 months on mortality and kidney graft survival over 10 years. This retrospective single-center study included 114 adult patients who underwent an SPKT between 2005 and 2018. (3) Results: Pancreas graft survival rate was 85.1% at 3 months. The main causes of early pancreas graft loss were thrombosis (6.1%), necrosis (2.6%), and pancreatitis (2.6%). Early pancreas graft loss was not associated with reduced patient survival (p = 0.168) or major adverse cerebral or cardiovascular events over 10 years (p = 0.741) compared to patients with functioning pancreas, after 3 months. Moreover, kidney graft function (p = 0.494) and survival (p = 0.461) were not significantly influenced by early pancreas graft loss. (4) Conclusion: In this study, using the landmark analysis technique, early pancreas graft loss within 3 months did not significantly impact patient or kidney graft survival over 10 years.

Greater early pancreas graft loss in women compared with men after simultaneous pancreas-kidney transplantation

2005 ◽  
Vol 19 (2) ◽  
pp. 158-161 ◽  
Author(s):  
Christopher Colling ◽  
R Brian Stevens ◽  
Elizabeth Lyden ◽  
James Lane ◽  
Lynn Mack-Shipman ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Graft Loss ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Simultaneous Pancreas Kidney Transplantation ◽  
Pancreas Graft

RISK FACTORS AND IMPACT OF CYTOMEGALOVIRUS DISEASE IN SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTATION

2001 ◽  
Vol 72 (12) ◽  
pp. 1940-1945 ◽  
Author(s):  
Dixon B. Kaufman ◽  
Joseph R. Leventhal ◽  
Lorenzo G. Gallon ◽  
Michele A. Parker ◽  
Alan J. Koffron ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Transplantation ◽  
Cytomegalovirus Disease ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Simultaneous Pancreas Kidney Transplantation

scholarly journals Subcapsular Renal Hematoma in Simultaneous Pancreas Kidney Transplantation

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Daniele Cappellani ◽  
Chiara Terrenzio ◽  
Elena Gianetti ◽  
Walter Baronti ◽  
Valerio Borrelli ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
High Risk ◽  
Graft Loss ◽  
Hemodynamic Instability ◽  
Kidney Transplant Recipients ◽  
Excessive Pressure ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Renal Rupture ◽  
Simultaneous Pancreas Kidney Transplantation

Subcapsular renal hematoma (SRH) is a challenging condition, which may jeopardize kidney function or constitute a life-threatening event. This is particularly true in single-kidney patients, such as kidney-transplant recipients. SRH may exert an excessive pressure on the surrounding parenchyma, thus resulting in hypoperfusion and ischemia, with high risk of acute kidney failure and graft loss. Moreover, SRH may precede an overt renal rupture with subsequent hemorrhage and hemodynamic instability. The indication to an interventional management for this condition is still a matter of debate, with some authors advocating the high possibilities of spontaneous resolution and others advocating the high-risk of graft loss and even internal bleeding in case of overt renal rupture. Herein, we report the case of a 51-year-old simultaneous pancreas-kidney transplantation recipient who presented a SRH following a mild trauma. The therapeutic choices were carefully balanced on the specific case, and the conservative management proved successful.

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