Case Report of Hepatic Mucormycosis After Liver Transplantation: Successful Treatment With Liposomal Amphotericin B Followed by Posaconazole Sequential Therapy

2012 ◽  
Vol 44 (8) ◽  
pp. 2501-2502 ◽  
Author(s):  
C.S. Abboud ◽  
M.D. Bergamasco ◽  
C.E.S. Baía ◽  
M.P. Lallée ◽  
A.S.C. Zan ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Report ◽  
Amphotericin B ◽  
Successful Treatment ◽  
Liposomal Amphotericin ◽  
Sequential Therapy ◽  
Liposomal Amphotericin B

scholarly journals Clinical Challenges in the Management of Leishmania/HIV Coinfection in a Nonendemic Area: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
K. Grabmeier-Pfistershammer ◽  
W. Poeppl ◽  
P. M. Brunner ◽  
K. Rappersberger ◽  
A. Rieger
Keyword(s):  
Case Report ◽  
Visceral Leishmaniasis ◽  
Amphotericin B ◽  
Liposomal Amphotericin ◽  
Sequential Therapy ◽  
Liposomal Amphotericin B ◽  
Hiv Positive ◽  
Treatment Regimens ◽  
Hiv Coinfection ◽  
Immunosuppressed Patients

We report on a 37-year-old male HIV-positive patient with generalized cutaneous leishmaniasis undiagnosed for several years. Upon presentation, visceral leishmaniasis was diagnosed in addition to cutaneous manifestation of the disease. Over a period of three years, several different treatment regimens including liposomal amphotericin B, liposomal amphotericin B with miltefosine, liposomal amphotericin B with interferon, and pentamidine combined fluconazole and allopurinol were applied until Leishmania PCR from blood turned negative. This case supports the necessity of multidrug combinational and sequential therapy over a very prolonged period of time in severely immunosuppressed patients infected with Leishmania and highlights the tremendous individual but also economic burden of this disease.

scholarly journals Disseminated fusariosis in a pediatric patient with acute lymphoblastic leukemia and prolonged fever - a case report

2018 ◽  
Vol 71 (9-10) ◽  
pp. 314-318
Author(s):  
Natasa Kacanski ◽  
Branislava Radisic ◽  
Jovanka Kolarovic
Keyword(s):  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Amphotericin B ◽  
Liposomal Amphotericin ◽  
Lymphoblastic Leukemia ◽  
Fusarium Species ◽  
Water System ◽  
Liposomal Amphotericin B ◽  
Fusarium Infection ◽  
Days Of Therapy

Introduction. Infections caused by fungi of Fusarium species occur in immunocompromised individuals as disseminated diseases. Case Report. This case report presents a 5-year-old boy with acute lymphoblastic leukemia who developed a disseminated fusarium infection during reinduction chemotherapy. Fever was the main symptom and it lasted for 15 weeks. Refractory fever despite broad-spectrum antibiotics, as well as nausea, myalgia, pulmonary symptoms with detection of pulmonary infiltrates, liver and spleen involvement indicated an invasive fungal infection. The patient received fluconazole, voriconazole, liposomal amphotericin B and caspofungin. Since high temperature was persistent, diagnostic laparoscopy of the abdomen was done. Scattered lesions, up to 2 mm in diameter, were observed macroscopically on the surface of the liver and spleen. The liver culture was positive for Acinetobacter and Fusarium species. After 38 days of therapy with liposomal amphotericin B and 3 days of ciprofloxacin, the patient became afebrile. Itraconazole (according to the antimycogram) was continued during maintenance therapy. Abdominal ultrasound was completely normal after 5 months of treatment with itraconazole. This boy was our first patient with a disseminated fusarium infection. At that time, Fusarium was detected in the hospital water system and in hospital air samples. Conclusion. A timely diagnosis of invasive fungal diseases in children is a big challenge. Over the past decade, there has been an increase in survival rate of patients with invasive fusariosis due to much more common use of voriconazole or combined antifungal therapy.

High-dose Weekly Liposomal Amphotericin B Antifungal Prophylaxis in Patients Undergoing Liver Transplantation

2015 ◽  
Vol 99 (4) ◽  
pp. 848-854 ◽  
Author(s):  
Maddalena Giannella ◽  
Giorgio Ercolani ◽  
Francesco Cristini ◽  
Mariacristina Morelli ◽  
Michele Bartoletti ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Amphotericin B ◽  
Liposomal Amphotericin ◽  
Antifungal Prophylaxis ◽  
Liposomal Amphotericin B ◽  
High Dose

Mediastinal Mucormycosis: Case report, review of literature and treatment with continuous liposomal amphotericin B irrigation

Mycoses ◽  
2019 ◽  
Author(s):  
Joseph D. Cooper ◽  
Robert A. Gotoff ◽  
Michael A. Foltzer ◽  
Russell A. Carter ◽  
Thomas J. Walsh
Keyword(s):  
Case Report ◽  
Amphotericin B ◽  
Liposomal Amphotericin ◽  
Liposomal Amphotericin B ◽  
Review Of Literature

Successful treatment of focal hepatic candidiasis with liposomal amphotericin B

1992 ◽  
Vol 161 (12) ◽  
pp. 664-665 ◽  
Author(s):  
B. O’Connell ◽  
G. Crotty ◽  
M. T. Cafferkey ◽  
R. Stephens ◽  
G. S. A. McDonald ◽  
...  
Keyword(s):  
Amphotericin B ◽  
Successful Treatment ◽  
Liposomal Amphotericin ◽  
Liposomal Amphotericin B
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