Donor-Recipient Gender Mismatch Affects Early Graft Loss After Kidney Transplantation

2011 ◽  
Vol 43 (8) ◽  
pp. 2914-2916 ◽  
Author(s):  
M. Żukowski ◽  
K. Kotfis ◽  
J. Biernawska ◽  
M. Zegan-Barańska ◽  
M. Kaczmarczyk ◽  
...  
2014 ◽  
Vol 98 ◽  
pp. 629-630 ◽  
Author(s):  
M. Hamed ◽  
L. Pasea ◽  
J. Bradley ◽  
G. Pettigrew ◽  
K. Saeb-Parsy

2015 ◽  
Vol 15 (6) ◽  
pp. 1632-1643 ◽  
Author(s):  
M. O. Hamed ◽  
Y. Chen ◽  
L. Pasea ◽  
C. J. Watson ◽  
N. Torpey ◽  
...  

2020 ◽  
Vol 97 (6) ◽  
pp. 1243-1252 ◽  
Author(s):  
Michèle J. de Kok ◽  
Alexander F. Schaapherder ◽  
Jacobus W. Mensink ◽  
Aiko P. de Vries ◽  
Marlies E. Reinders ◽  
...  

2021 ◽  
Author(s):  
Tamar A. J. van den Berg ◽  
Ton Lisman ◽  
Frank J.M.F. Dor ◽  
Cyril Moers ◽  
Robert C. Minnee ◽  
...  

In kidney transplantation (KTx), renal graft thrombosis (RGT) is one of the main reasons for early graft loss. Although evidence-based guidance on prevention of RGT is lacking, thromboprophylaxis is widely used. The aim of this survey was to obtain a European view of the different thromboprophylactic strategies applied in KTx. An online 22-question survey, addressed to KTx professionals, was distributed by e-mail and via platforms of the European Society for Organ Transplantation. Seventy-five responses (21 countries, 51 centers) were received: 75% had over 10 years’ clinical experience, 64% were surgeons, 29% nephrologists and 4% urologists. A written antithrombotic management protocol was available in 75% of centers. In 8 (16%) of centers respondents contradicted each other regarding the availability of a written protocol. Thromboprophylaxis is preferred by 78% of respondents, independent of existing antithrombotic management protocols. Ninety-two percent of respondents indicated that an anticipated bleeding risk is the main reason to discontinue chronic antithrombotic therapy preoperatively. Intraoperatively, 32% of respondents administer unfractionated heparin (400 – 10.000 international units with a median of 5000) in selected cases. Despite an overall preference for perioperative thromboprophylaxis in KTx, there is a high variation within Europe regarding type, timing and dosage, most likely due to the paucity of high-quality studies. Further research is warranted in order to develop better guidelines.


2013 ◽  
Vol 45 (3) ◽  
pp. 1070-1072 ◽  
Author(s):  
M. Raimundo ◽  
J. Guerra ◽  
C. Teixeira ◽  
A. Santana ◽  
S. Silva ◽  
...  

2021 ◽  
Vol 10 (15) ◽  
pp. 3237
Author(s):  
Lukas Johannes Lehner ◽  
Robert Öllinger ◽  
Brigitta Globke ◽  
Marcel G. Naik ◽  
Klemens Budde ◽  
...  

(1) Background: Simultaneous pancreas–kidney transplantation (SPKT) is a standard therapeutic option for patients with diabetes mellitus type I and kidney failure. Early pancreas allograft failure is a complication potentially associated with worse outcomes. (2) Methods: We performed a landmark analysis to assess the impact of early pancreas graft loss within 3 months on mortality and kidney graft survival over 10 years. This retrospective single-center study included 114 adult patients who underwent an SPKT between 2005 and 2018. (3) Results: Pancreas graft survival rate was 85.1% at 3 months. The main causes of early pancreas graft loss were thrombosis (6.1%), necrosis (2.6%), and pancreatitis (2.6%). Early pancreas graft loss was not associated with reduced patient survival (p = 0.168) or major adverse cerebral or cardiovascular events over 10 years (p = 0.741) compared to patients with functioning pancreas, after 3 months. Moreover, kidney graft function (p = 0.494) and survival (p = 0.461) were not significantly influenced by early pancreas graft loss. (4) Conclusion: In this study, using the landmark analysis technique, early pancreas graft loss within 3 months did not significantly impact patient or kidney graft survival over 10 years.


Sign in / Sign up

Export Citation Format

Share Document