Influence of Cyclosporine and Tacrolimus on Serum Uric Acid Levels in Stable Kidney Transplant Recipients

2005 ◽  
Vol 37 (7) ◽  
pp. 3119-3120 ◽  
Author(s):  
M. Kanbay ◽  
A. Akcay ◽  
B. Huddam ◽  
C.A. Usluogullari ◽  
Z. Arat ◽  
...  
Keyword(s):  
Uric Acid ◽  
Kidney Transplant ◽  
Serum Uric Acid ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

Effect of Oral Fructose Load on Serum Uric Acid and Lipids in Kidney Transplant Recipients Treated With Cyclosporine or Tacrolimus

2009 ◽  
Vol 41 (1) ◽  
pp. 188-191 ◽  
Author(s):  
A. Zawiasa ◽  
M. Szklarek-Kubicka ◽  
J. Fijałkowska-Morawska ◽  
D. Nowak ◽  
J. Rysz ◽  
...  
Keyword(s):  
Uric Acid ◽  
Kidney Transplant ◽  
Serum Uric Acid ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients

scholarly journals Serum uric acid is associated with increased risk of posttransplantation diabetes in kidney transplant recipients: a prospective cohort study

Metabolism ◽  
2021 ◽  
Vol 116 ◽  
pp. 154465
Author(s):  
Camilo G. Sotomayor ◽  
Sara Sokooti Oskooei ◽  
Nicolás I. Bustos ◽  
Ilja M. Nolte ◽  
António W. Gomes-Neto ◽  
...  
Keyword(s):  
Uric Acid ◽  
Cohort Study ◽  
Kidney Transplant ◽  
Serum Uric Acid ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Increased Risk

A Cross-Sectional Study of the Association Between Chronic Oral Disease Burden and Serum Biomarkers in Kidney Transplant Recipients

2021 ◽  
pp. 152692482110648
Author(s):  
Layna Cristine Brito Rocha ◽  
Danila Lorena Nunes-dos-Santos ◽  
Elisa Miranda Costa ◽  
Samira Vasconcelos Gomes ◽  
Vandilson Pinheiro Rodrigues ◽  
...  
Keyword(s):  
Uric Acid ◽  
Kidney Transplant ◽  
Disease Burden ◽  
Serum Biomarkers ◽  
Oral Disease ◽  
Categorical Variables ◽  
Continuous Variables ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Cross Sectional

Introduction Poor oral health can negatively affect general health and quality of life of kidney transplant recipients. The study aimed to investigate the association between chronic oral disease burden, serum biomarkers, and comorbidities in kidney transplant recipients. Design A cross-sectional comparative study was conducted with 44 patients after kidney transplant. The burden of chronic oral disease was composed of the following observable variables: moderate periodontitis and presence of dental caries. Serum biomarkers and comorbidities data were collected. The chi-square or Fisher's exact tests for categorical variables and Student's t-test or Mann–Whitney test for continuous variables were used. Robust Poisson regression was used to model the association. Results Higher levels of mean uric acid ( P = .01) and creatinine ( P = .03) were observed in the group of patients with oral disease burden, while the highest level of high-density lipoprotein was observed in the group without oral disease. Higher values of uric acid were associated with the occurrence of chronic oral disease burden (Adjusted PR = 1.24, 95% CI: 1.03-1.48, P = .019). There was no statistical difference between the groups with and without oral disease burden in comorbidities present. Conclusion The findings suggest that chronic oral diseases burden can be associated with uric acid and creatinine levels in kidney transplant recipients.

Uric acid and clinical correlates of endothelial function in kidney transplant recipients

2014 ◽  
Vol 28 (10) ◽  
pp. 1167-1176 ◽  
Author(s):  
Dag Olav Dahle ◽  
Trond Jenssen ◽  
Hallvard Holdaas ◽  
Anders Åsberg ◽  
Inga Soveri ◽  
...  
Keyword(s):  
Uric Acid ◽  
Endothelial Function ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Clinical Correlates

scholarly journals THE EFFECT OF HYPERURICEMIA AND ALLOPURINOL ON OUTCOME OF KIDNEY TRANSPLANT RECIPIENTS

2021 ◽  
Author(s):  
Ersin Nazlican ◽  
Neshat Yucel ◽  
Saime Paydas ◽  
Ilker Unal
Keyword(s):  
Uric Acid ◽  
Retrospective Study ◽  
Confidence Interval ◽  
Kidney Transplant ◽  
Low Dose ◽  
Graft Loss ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Renal Functions ◽  
The Mean

OBJECTİVE: Kidney transplant recipients (KTRs) may have increased serum uric acid (SUA) level due to presence of existing greft dysfunction and used immunosuppressives. In this retrospective study, we evaluated effect of high SUA levels and allopurinol therapy in KTRs on renal functions. PATIENTS and METHODS: 113 KTRs of 233 KTRs included, had elevated SUA level (G1). Fiftyseven of G1 received allopurinol treatment (G1A+) and 56 patients (G1A-) did not. 56 of 118 patients who were followed for five years (G5) were hyperuricemic (G5-1) and 26 of G5-1 treated with allopurinol (G5-1A+) and 30 of them did not (G5-1A-). 62 patients were normourisemic (G5-2). RESULTS: Of the 233 patients included the mean age was 42.8±11.6 (17-76), 164 were male (70.0%). In 2. year graft loss developed in 9 (7.5 %) and 18 (15.9%) of G2 and G1 respectively (p = 0.045). According to allopurinol therapy 10 of the graft loss occurred in the G1A+ and 8 in the G1A- (p=0,330). Graft loss occurred in 12 (21%) and 9 (14%) in G5-1 and G5-2 respectively (p = 0.62). Graft loss occurred in 7 (23 %) and 5 (19%) in G5-1A+ and G5-1A- respectively P = 0.71). Considering the first 2 in G5; in G5-1 graft loss was higher than in the G5-2 (p = 0.023), and higher SUA levels increased the graft loss by 3.6 times compared to normal SUA levels (95% confidence interval: 1,2-12.70). CONCLUSION: There was a significant relationship between high SUA levels and graf loss in kidney transplant recipients in 2 years and 5 years. Treatment of high SUA with alIopurinol therapy had protective effect on renal functions. So that hyperuricemia should be treated and low dose allopurinol can be option for treatment of hyperuricemia therefore prevention of loss of kidney function in kidney transplant recipients.

Uric acid has a J-shaped association with cardiovascular and all-cause mortality in kidney transplant recipients

2013 ◽  
Vol 28 (1) ◽  
pp. 134-140 ◽  
Author(s):  
Dag Olav Dahle ◽  
Trond Jenssen ◽  
Hallvard Holdaas ◽  
Torbjørn Leivestad ◽  
Mari Vårdal ◽  
...  
Keyword(s):  
Uric Acid ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
All Cause Mortality
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