Risk factors for graft loss in patients with recurrent IGA nephropathy after renal transplantation

2004 ◽  
Vol 36 (5) ◽  
pp. 1314-1316 ◽  
Author(s):  
Y Namba ◽  
K Oka ◽  
T Moriyama ◽  
N Ichimaru ◽  
M Kyo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Transplantation ◽  
Iga Nephropathy ◽  
Graft Loss ◽  
Recurrent Iga Nephropathy

scholarly journals Recurrence of IgA Nephropathy after Kidney Transplantation in Adults

2021 ◽  
Vol 16 (8) ◽  
pp. 1247-1255
Author(s):  
Audrey Uffing ◽  
Maria José Pérez-Saéz ◽  
Thomas Jouve ◽  
Mathilde Bugnazet ◽  
Paolo Malvezzi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Transplantation ◽  
Confidence Interval ◽  
Iga Nephropathy ◽  
Graft Loss ◽  
Hazard Ratio ◽  
Content Type ◽  
Specific Antibodies ◽  
Donor Specific Antibodies ◽  
Recurrent Iga Nephropathy

Background and objectivesIn patients with kidney failure due to IgA nephropathy, IgA deposits can recur in a subsequent kidney transplant. The incidence, effect, and risk factors of IgA nephropathy recurrence is unclear, because most studies have been single center and sample sizes are relatively small.Design, setting, participants, & measurementsWe performed a multicenter, international, retrospective study to determine the incidence, risk factors, and treatment response of recurrent IgA nephropathy after kidney transplantation. Data were collected from all consecutive patients with biopsy-proven IgA nephropathy transplanted between 2005 and 2015, across 16 “The Post-Transplant Glomerular Disease” study centers in Europe, North America, and South America.ResultsOut of 504 transplant recipients with IgA nephropathy, recurrent IgA deposits were identified by kidney biopsy in 82 patients; cumulative incidence of recurrence was 23% at 15 years (95% confidence interval, 14 to 34). Multivariable Cox regression revealed a higher risk for recurrence of IgA deposits in patients with a pre-emptive kidney transplant (hazard ratio, 3.45; 95% confidence interval, 1.31 to 9.17) and in patients with preformed donor-specific antibodies (hazard ratio, 2.59; 95% confidence interval, 1.09 to 6.19). After kidney transplantation, development of de novo donor-specific antibodies was associated with subsequent higher risk of recurrence of IgA nephropathy (hazard ratio, 6.65; 95% confidence interval, 3.33 to 13.27). Immunosuppressive regimen was not associated with recurrent IgA nephropathy in multivariable analysis, including steroid use. Graft loss was higher in patients with recurrence of IgA nephropathy compared with patients without (hazard ratio, 3.69; 95% confidence interval, 2.04 to 6.66), resulting in 32% (95% confidence interval, 50 to 82) graft loss at 8 years after diagnosis of recurrence.ConclusionsIn our international cohort, cumulative risk of IgA nephropathy recurrence increased after transplant and was associated with a 3.7-fold greater risk of graft loss.

scholarly journals Recurrent IgA nephropathy after renal transplantation despite immunosuppressive regimens with mycophenolate mofetil

2005 ◽  
Vol 20 (6) ◽  
pp. 1214-1221 ◽  
Author(s):  
Arun Chandrakantan ◽  
Piti Ratanapanichkich ◽  
Mowaffaq Said ◽  
Catherine V. Barker ◽  
Bruce A. Julian
Keyword(s):  
Mycophenolate Mofetil ◽  
Renal Transplantation ◽  
Iga Nephropathy ◽  
Recurrent Iga Nephropathy

A clinicopathological study of recurrent IgA nephropathy following renal transplantation in children

Nephrology ◽  
2003 ◽  
Vol 8 (s4) ◽  
pp. A115-A115
Author(s):  
Hiroko CHIKAMOTO ◽  
Motoshi HATTORI ◽  
Shigeru HORITA ◽  
Toshihiro SAWAI ◽  
Tae OHMORI ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Iga Nephropathy ◽  
Clinicopathological Study ◽  
Recurrent Iga Nephropathy

Risk Factors for Graft Loss Due to Acute Vascular Complications in Adult Renal Transplantation Using Grafts Without Vascular Anomalies

2019 ◽  
Vol 51 (9) ◽  
pp. 2939-2942 ◽  
Author(s):  
Gian Luigi Adani ◽  
Riccardo Pravisani ◽  
Umberto Baccarani ◽  
Matteo Faion ◽  
Sara Crestale ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Transplantation ◽  
Graft Loss ◽  
Vascular Complications ◽  
Vascular Anomalies

Recurrent IgA nephropathy after renal transplantation and steroid withdrawal

2018 ◽  
Vol 32 (4) ◽  
pp. e13207 ◽  
Author(s):  
Maria Cristina Di Vico ◽  
Maria Messina ◽  
Fabrizio Fop ◽  
Antonella Barreca ◽  
Giuseppe Paolo Segoloni ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Iga Nephropathy ◽  
Steroid Withdrawal ◽  
Recurrent Iga Nephropathy

IgA serology in recurrent and non-recurrent IgA nephropathy after renal transplantation

1995 ◽  
Vol 10 (12) ◽  
pp. 2310-2315 ◽  
Author(s):  
R. Coppo ◽  
A. Amore ◽  
P. Cirina ◽  
M. Messina ◽  
B. Basolo ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Iga Nephropathy ◽  
Recurrent Iga Nephropathy

RISK FACTORS FOR GRAFT LOSS AFTER INITIALLY SUCCESSFUL RENAL TRANSPLANTATION.

1998 ◽  
Vol 65 (12) ◽  
pp. S145
Author(s):  
C. A. Stegeman ◽  
J. Broekroelofs ◽  
S.P.M. Lems ◽  
W. J. van Son ◽  
P. E. de Jong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Renal Transplantation ◽  
Graft Loss

scholarly journals Tonsillectomy in Recurrent IgA Nephropathy after Renal Transplantation

2012 ◽  
Vol 115 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Natsuko Kurata ◽  
Masatoki Takahashi ◽  
Hiroko Koda
Keyword(s):  
Renal Transplantation ◽  
Iga Nephropathy ◽  
Recurrent Iga Nephropathy

scholarly journals Tonsillectomy for Recurrent IgA Nephropathy Following Renal Transplantation

2006 ◽  
Vol 99 (6) ◽  
pp. 467-471 ◽  
Author(s):  
Yushi Ueki ◽  
Hideo Shinoda ◽  
Takashi Kawasaki ◽  
Sugata Takahashi
Keyword(s):  
Renal Transplantation ◽  
Iga Nephropathy ◽  
Recurrent Iga Nephropathy
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