scholarly journals Prognostic Significance of Decreased Expression of Six Large Common Fragile Site Genes in Oropharyngeal Squamous Cell Carcinomas

2014 ◽  
Vol 7 (6) ◽  
pp. 726-731 ◽  
Author(s):  
Ge Gao ◽  
Jan L. Kasperbauer ◽  
Nicole M. Tombers ◽  
Melissa D. Cornell ◽  
David I. Smith
Keyword(s):  
Squamous Cell ◽  
Fragile Site ◽  
Prognostic Significance ◽  
Squamous Cell Carcinomas ◽  
Common Fragile Site

A selected group of large common fragile site genes have decreased expression in oropharyngeal squamous cell carcinomas

2014 ◽  
Vol 53 (5) ◽  
pp. 392-401 ◽  
Author(s):  
Ge Gao ◽  
Jan L. Kasperbauer ◽  
Nicole M. Tombers ◽  
Vivian Wang ◽  
Kevin Mayer ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Fragile Site ◽  
Squamous Cell Carcinomas ◽  
Common Fragile Site

Differential loss of expression of common fragile site genes between oral tongue and oropharyngeal squamous cell carcinomas

2008 ◽  
Vol 121 (3-4) ◽  
pp. 201-210 ◽  
Author(s):  
C. Soderberg ◽  
D.S. Perez ◽  
O.C. Ukpo ◽  
X. Liang ◽  
A.G. O’Reilly ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Fragile Site ◽  
Squamous Cell Carcinomas ◽  
Common Fragile Site ◽  
Oral Tongue

Ultrastructural features of prognostic significance in human oral cancer

1992 ◽  
Vol 50 (1) ◽  
pp. 618-619
Author(s):  
Karvita B. Ahluwalia ◽  
Nidhi Sharma
Keyword(s):  
Oral Cancer ◽  
Squamous Cell ◽  
Common Knowledge ◽  
Prognostic Significance ◽  
Growth Control ◽  
Terminal Differentiation ◽  
Squamous Cell Carcinomas ◽  
Effective Therapy ◽  
Invasive Potential ◽  
Biological Behaviour

It is common knowledge that apparently similar tumors often show different responses to therapy. This experience has generated the idea that histologically similar tumors could have biologically distinct behaviour. The development of effective therapy therefore, has the explicit challenge of understanding biological behaviour of a tumor. The question is which parameters in a tumor could relate to its biological behaviour ? It is now recognised that the development of malignancy requires an alteration in the program of terminal differentiation in addition to aberrant growth control. In this study therefore, ultrastructural markers that relate to defective terminal differentiation and possibly invasive potential of cells have been identified in human oral leukoplakias, erythroleukoplakias and squamous cell carcinomas of the tongue.

The Majority of Cutaneous Squamous Cell Carcinomas Arise in Actinic Keratoses

2002 ◽  
Vol 6 (3) ◽  
pp. 207-209 ◽  
Author(s):  
D. Czarnecki ◽  
C. J. Meehan ◽  
F. Bruce ◽  
G. Culjak
Keyword(s):  
Family History ◽  
Squamous Cell ◽  
Retrospective Studies ◽  
Prognostic Significance ◽  
Squamous Cell Carcinomas ◽  
Histological Features ◽  
Actinic Keratoses ◽  
Skin Cancers ◽  
History Of ◽  
A Prospective Study

Background: Retrospective studies have given conflicting results with respect to how many cutaneous squamous cell carcinomas (SCCs) arise in actinic keratoses (AK). Objective: This study was conducted to determine what percentage of SCCs arise in AKs and to obtain more information about two histological features of SCCs, namely, thickness and ulceration. Methods: A prospective study was done of all SCCs treated by the authors during one calendar year. Results: Two hundred eight patients with SCC were entered into the study. An AK was contiguous with an SCC in 72% of the cases. This was taken as evidence that the SCC arose in the AK. Men presented with thicker and more ulcerated SCCs than women, but these were not statistically significant: p = 0.06 for thickness and p = 0.07 for ulceration. Ulcerated SCCs were more likely to arise on the head and neck (p = 0.02), on patients who had multiple skin cancers ( p = 0.005), and on patients who had a family history of skin cancer ( p = 0.03). Conclusion: Actinic keratoses need to be removed before they turn into SCCs. The prognostic significance of ulceration of cutaneous SCCs needs to be determined.

Prognostic significance of macrophage polarization in early stage oral squamous cell carcinomas

Oral Oncology ◽  
2016 ◽  
Vol 52 ◽  
pp. 75-84 ◽  
Author(s):  
Manuel Weber ◽  
Christos Iliopoulos ◽  
Patrick Moebius ◽  
Maike Büttner-Herold ◽  
Kerstin Amann ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Early Stage ◽  
Macrophage Polarization ◽  
Prognostic Significance ◽  
Squamous Cell Carcinomas ◽  
Oral Squamous Cell Carcinomas

Prognostic significance of DNA ploidy in oral squamous cell carcinomas

1995 ◽  
Vol 79 (1) ◽  
pp. 68-76 ◽  
Author(s):  
G. Baretton ◽  
Xun Li ◽  
C. Stoll ◽  
E. Fischer-Brandies ◽  
M. Schmidt ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Dna Ploidy ◽  
Prognostic Significance ◽  
Squamous Cell Carcinomas ◽  
Oral Squamous Cell Carcinomas

scholarly journals Prognostic Significance of p16 and Its Relationship With Human Papillomavirus in Pharyngeal Squamous Cell Carcinomas

2014 ◽  
Vol 140 (7) ◽  
pp. 647 ◽  
Author(s):  
David D. Wilson ◽  
Edwin F. Crandley ◽  
Austin Sim ◽  
Edward B. Stelow ◽  
Neil Majithia ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Squamous Cell ◽  
Prognostic Significance ◽  
Squamous Cell Carcinomas
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