Constrained evolution of a quantitative character by pleiotropic mutation

2005 ◽  
Vol 68 (4) ◽  
pp. 243-251 ◽  
Author(s):  
Y. Tanaka
Keyword(s):  
Quantitative Character ◽  
Constrained Evolution ◽  
Pleiotropic Mutation

Analysis of the Most Valued Organization to Work for in Spain, According to Nationality and Location

2019 ◽  
Vol 5 (2) ◽  
pp. 83-99
Author(s):  
Francisco Jesús Ferreiro Seoane ◽  
Manuel Octavio Del Campo Villares
Keyword(s):  
Work Environment ◽  
Talent Management ◽  
Point Of View ◽  
Added Value ◽  
Quantitative Character ◽  
Autonomous Communities ◽  
Professional Performance ◽  
Significant Relationships ◽  
Pearson Correlations ◽  
Selection Of

Background: The objective of this article is to analyse if there are significant relationships between the most valuable companies operating in Spain regarding professional performance, according to nationality and location within their Autonomous Communities or any superior aggrupation. To do that, a sample of 100 companies has been selected. Methods: The methodology followed is based on the selection of the 100 highestvalued companies from the point of view of Human Resources’ policy for the period 2013-2016 and through the measurement of six factors: Talent Management, Retribution, Work environment, CSR, Training and Employees’ perception, and classified by nationality and location. The study was based on 12 hypotheses, using the Unifactorial Variance’s Analysis, Pearson correlations and regressions. One limitation could be the fact that this study refers to a particular period, focusing on Spain and the variables mentioned, based on questionnaires. The added value of this work lies on the newness as it has a quantitative character, and on the fact that most of the hypotheses do not comply. Results and Conclusion: This allows to deny certain beliefs that affirm that European and American companies operating in Spain are more attractive than the Spanish or the Mediterranean ones.

scholarly journals Assessing Commensality in Research

2021 ◽  
Vol 18 (5) ◽  
pp. 2632
Author(s):  
Henrik Scander ◽  
Agneta Yngve ◽  
Maria Lennernäs Wiklund
Keyword(s):  
Mixed Methods Research ◽  
Dietary Assessment ◽  
Research Field ◽  
Dietary Quality ◽  
Quantitative Character ◽  
Dietary Recall ◽  
Health And Wellbeing ◽  
Dietary Surveys ◽  
Health Related ◽  
Empirical Material

This scoping review focuses on the assessment of commensality in research and attempts to identify used methods for performing research on commensality. It reflects a multidisciplinary research field and draws on findings from Web of Science Core Collection, up to April 2019. The empirical material consisted of 61 studies, whereof most were qualitative research, and some were of quantitative character, including very few dietary surveys. The findings show nine papers categorized as using quantitative approaches, 52 papers were categorized as qualitative. The results show a wide variety of different ways to try to find and understand how commensality can be understood and identified. There seems to be a shift in the very concept of commensality as well as some variations around the concept. This paper argues the need to further investigate the importance of commensality for health and wellbeing, as well as the need to gather data on health and health-related behaviors, living conditions and sociodemographic data in parallel. The review shows the broad-ranging areas where commensality is researched, from cultural and historical areas to ethnographic or anthropological areas over to dietary assessment. To complement large dietary surveys with methods of assessing who you are eating with in what environment should be a simple way to further our knowledge on the circumstances of meal intake and the importance of commensality. To add 24-h dietary recall to any study of commensality is another way of identifying the importance of commensality for dietary quality. The use of mixed methods research was encouraged by several authors as a good way forward in the assessment of commensality and its importance.

scholarly journals How informative is Wright's estimator of the number of genes affecting a quantitative character?

Genetics ◽  
1990 ◽  
Vol 126 (1) ◽  
pp. 235-247 ◽  
Author(s):  
Z B Zeng ◽  
D Houle ◽  
C C Cockerham
Keyword(s):  
Genetic Variance ◽  
Estimation Procedure ◽  
Expected Value ◽  
Allele Frequencies ◽  
Quantitative Character ◽  
Base Population ◽  
Single Population ◽  
Number Of Genes ◽  
Selection Limit ◽  
The Difference

Abstract S. Wright suggested an estimator, m, of the number of loci, m, contributing to the difference in a quantitative character between two differentiated populations, which is calculated from the phenotypic means and variances in the two parental populations and their F1 and F2 hybrids. The same method can also be used to estimate m contributing to the genetic variance within a single population, by using divergent selection to create differentiated lines from the base population. In this paper we systematically examine the utility and problems of this technique under the influences of unequal allelic effects and initial allele frequencies, and linkage, which are known to lead m to underestimate m. In addition, we examine the effects of population size and selection intensity during the generations of selection. During selection, the estimator m rapidly approaches its expected value at the selection limit. With reasonable assumptions about unequal allelic effects and initial allele frequencies, the expected value of m without linkage is likely to be on the order of one-third of the number of genes. The estimates suffer most seriously from linkage. The practical maximum expectation of m is just about the number of chromosomes, considerably less than the "recombination index" which has been assumed to be the upper limit. The estimates are also associated with large sampling variances. An estimator of the variance of m derived by R. Lande substantially underestimates the actual variance. Modifications to the method can ameliorate some of the problems. These include using F3 or later generation variances or the genetic variance in the base population, and replicating the experiments and estimation procedure. However, even in the best of circumstances, information from m is very limited and can be misleading.

scholarly journals The mac1 Gene: Controlling the Commitment to the Meiotic Pathway in Maize

Genetics ◽  
1996 ◽  
Vol 142 (3) ◽  
pp. 1009-1020 ◽  
Author(s):  
William F Sheridan ◽  
Nadezhda A Avalkina ◽  
Ivan I Shamrov ◽  
Tatyana B Batyea ◽  
Inna N Golubovskaya
Keyword(s):  
Female Gametophyte ◽  
Embryo Sac ◽  
Flowering Plants ◽  
Normal Female ◽  
Ovule Development ◽  
Partial Sterility ◽  
Embryo Sac Formation ◽  
Female Gametophyte Development ◽  
Normal Meiosis ◽  
Pleiotropic Mutation

Abstract The switch from the vegetative to the reproductive pathway of development in flowering plants requires the commitment of the subepidermal cells of the ovules and anthers to enter the meiotic pathway. These cells, the hypodermal cells, either directly or indirectly form the archesporial cells that, in turn, differentiate into the megasporocytes and microsporocytes. We have isolated a recessive pleiotropic mutation that we have termed multiple archesporial cells1 (macl) and located it to the short arm of chromosome 10. Its cytological phenotype suggests that this locus plays an important role in the switch of the hypodermal cells from the vegetative to the meiotic (sporogenous) pathway in maize ovules. During normal ovule development in maize, only a single hypodermal cell develops into an archesporial cell and this differentiates into the single megasporocyte. In macl mutant ovules several hypodermal cells develop into archesporial cells, and the resulting megasporocytes undergo a normal meiosis. More than one megaspore survives in the tetrad and more than one embryo sac is formed in each ovule. Ears on mutant plants show partial sterility resulting from abnormalities in megaspore differentiation and embryo sac formation. The sporophytic expression of this gene is therefore also important for normal female gametophyte development.

Developmental properties of shibirets1: A pleiotropic mutation affecting larval and adult locomotion and development

1973 ◽  
Vol 32 (2) ◽  
pp. 373-386 ◽  
Author(s):  
Clifton A. Poodry ◽  
Linda Hall ◽  
David T. Suzuki
Keyword(s):  
Pleiotropic Mutation

Constrained evolution of a bispecific enzyme: lessons for biocatalyst design

2017 ◽  
Vol 15 (4) ◽  
pp. 937-946 ◽  
Author(s):  
E. Sugrue ◽  
C. Scott ◽  
C. J. Jackson
Keyword(s):  
Protein Engineering ◽  
Natural Evolution ◽  
Constrained Evolution

Analysis of the natural evolution of bispecificity in triazine hydrolase highlights the importance of epistasis in protein engineering and evolution.

scholarly journals MODELAGEM, SIMULAÇÃO E OTIMIZAÇÃO DA DINÂMICA OPERACIONAL DO PROCESSO DE ATENDIMENTO DE UM PEQUENO POSTO DE SAÚDE

e-xacta ◽  
2013 ◽  
Vol 6 (1) ◽  
pp. 101
Author(s):  
José Airton Azevedo dos Santos ◽  
Tiago C. Dal’sotto ◽  
Wesley Schroeder
Keyword(s):  
Computer Simulation ◽  
Appointment Scheduling ◽  
Quantitative Character ◽  
Health Post ◽  
Waiting Room ◽  
Optimization Software ◽  
Simulation And Optimization ◽  
Medical Appointment ◽  
West Region ◽  
Simulation Package

<p>Este trabalho tem como objetivo analisar, através de técnicas de simulação e de otimização, a dinâmica operacional do processo de atendimento de um pequeno posto de saúde localizado na região oeste paranaense. A simulação e a otimização foram executadas utilizando o pacote de simulação Arena®, que inclui o software de otimização Optquest. A metodologia utilizada é a de modelagem através de simulação computacional, de caráter quantitativo e é caracterizada como participativa. A aplicação destas técnicas em conjunto resultaram na otimização do número de agendamento de consultas médicas do posto de saúde.</p><p>Abstract</p><p>This work aims to analyze the attending process operational dynamics of a small health post located in Paraná West Region. Another objective is connect the concepts of simulation and optimization to maximize the number of scheduling appointments for the health post, within the limits of accommodation of the waiting room. The simulation and optimization were performed using the Arena ® simulation package, which includes the OptQuest optimization software. The methodology used was the modeling through computer simulation of quantitative character and it is characterized as participative. The application of these techniques all together resulted in the optimization of the number of medical appointment scheduling of the health post</p>

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