An unusual, mild and convenient one-pot two-step access to (E)-stilbenes from hydroxy-substituted benzaldehydes and phenylacetic acids under microwave activation: a new facet of the classical Perkin reaction

Tetrahedron ◽  
2007 ◽  
Vol 63 (45) ◽  
pp. 11070-11077 ◽  
Author(s):  
Arun K. Sinha ◽  
Vinod Kumar ◽  
Abhishek Sharma ◽  
Anuj Sharma ◽  
Rakesh Kumar
Keyword(s):  
Microwave Activation ◽  
One Pot ◽  
Perkin Reaction ◽  
Substituted Benzaldehydes

An Expeditious One-Pot Three-Component Synthesis of 4-Aryl-3,4-dihydrobenzo[g] quinoline-2,5,10(1H)-triones under Green Conditions

2020 ◽  
Vol 23 (23) ◽  
pp. 2626-2634
Author(s):  
Saiedeh Kamalifar ◽  
Hamzeh Kiyani
Keyword(s):  
Reaction Medium ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
First Time ◽  
Green Conditions

: An efficient and facial one-pot synthesis of 4-aryl-3,4-dihydrobenzo[g]quinoline- 2,5,10(1H)-triones was developed for the first time. The process proceeded via the three-component cyclocondensation of 2-amino-1,4-naphthoquinone with Meldrum’s acid and substituted benzaldehydes under green conditions. The fused 3,4-dihydropyridin-2(1H)- one-ring naphthoquinones have been synthesized with good to high yields in refluxing ethanol as a green reaction medium. This protocol is simple and effective as well as does not involve the assistance of the catalyst, additive, or hazardous solvents.

A One-Pot, Three-Component, Solvent-Free Synthesis of Novel 6H-Chromeno[3’,4’:5,6]Pyrido[2,3-d]Pyrimidine-Triones under Microwave Irradiation

2018 ◽  
Vol 42 (12) ◽  
pp. 604-607
Author(s):  
Loghman Firoozpour ◽  
Hoda Yahyavi ◽  
Ramona Ejtemaei ◽  
Setareh Moghimi ◽  
Alireza Foroumadi
Keyword(s):  
Microwave Irradiation ◽  
Efficient Method ◽  
Barbituric Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
Solvent Free Synthesis

A green and efficient method for preparing novel heterocyclic systems is established through the reaction of differently substituted benzaldehydes, barbituric acid and 4-amino-2H-chromene-2-one under solvent-free conditions. This method affords 6H-chromeno[3’,4’:5,6] pyrido[2,3-d]pyrimidine-trione derivatives in high yields and short reaction times.

One-Pot Dry Media Synthesis of New Tetracyclic 1,5-Benzothiazepines under Microwave Activation.

ChemInform ◽  
2003 ◽  
Vol 34 (27) ◽  
Author(s):  
Anshu Dandia ◽  
Meha Sati ◽  
Kapil Arya ◽  
Andre Loupy
Keyword(s):  
Microwave Activation ◽  
One Pot

Microwave-assisted Efficient One-pot Synthesis of Nitriles Using Recyclable Magnetite (Fe3O4) Nanoparticles as Catalyst and Water as Solvent: A Greener Approach

2020 ◽  
Vol 10 (4) ◽  
pp. 507-517
Author(s):  
Prashant Chavan ◽  
Suhas Pednekar ◽  
Ramesh Chaughule ◽  
Anushree Lokur
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Reaction Medium ◽  
Chemical Yield ◽  
Significant Loss ◽  
Microwave Assisted Synthesis ◽  
Microwave Activation ◽  
One Pot ◽  
Microwave Assisted ◽  
Magnetite Fe3o4 ◽  
Water As Solvent

Background: There has been an increasing curiosity over the past few years to carry out organic reactions over heterogeneous nanocatalysts. Microwave activation coupled with a nanocatalyst along with water as a reaction medium makes the process further green. Microwave activation as a green process reduces reaction times, enhances product purity and improves chemical yield. Methods: Nitrile group chemistry has been explored by many researchers across the globe owing to its interesting properties and its importance in synthetic chemistry. Despite several methods being available for the synthesis of nitriles, microwave assisted synthesis of nitriles using Fe3O4 nanoparticles appears more promising. The present study is intended at developing a recyclable magnetite (Fe3O4) nanoparticles catalyzed protocol towards the synthesis of organonitrile derivatives using one pot reaction. Results: The above protocol incorporates the use of microwave for heating and water as reaction medium. Several substituted nitriles could be synthesized for excellent yields. The magnetite nanoparticles can be reused for new reaction without significant loss in activity. Conclusion: The experiment makes the protocol simple, environment friendly and economically feasible.

Lithium Perchlorate and Lithium Bromide Catalysed Solvent Free One Pot Rapid Synthesis of 3-Carboxycoumarins under Microwave Irradiation

2002 ◽  
Vol 2002 (1) ◽  
pp. 40-41 ◽  
Author(s):  
B.P. Bandgar ◽  
L.S. Uppalla ◽  
V.S. Sadavarte
Keyword(s):  
Microwave Irradiation ◽  
Lithium Bromide ◽  
Lithium Perchlorate ◽  
Catalytic Amount ◽  
Solvent Free ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
Rapid Synthesis ◽  
One Pot ◽  
Substituted Benzaldehydes

Reaction of 2-hydroxy or 2-methoxy substituted benzaldehydes or acetophenones with Meldrum's acid in the presence of a catalytic amount of LiClO4 or LiBr without solvent under microwave irradiation afforded 3-carboxycoumarins in excellent yields.

scholarly journals Metal-free Catalyzed One-Pot Multicomponent Synthesis of (E)-3-(2-((5-(Benzylideneamino)-1,3,4-thiadiazol-2-yl)thio) Acetyl)-2H-chromen-2-one Derivatives and Their Biological Evaluation

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Shivanand Merugu ◽  
Vijaya Kumar Ponnamaneni ◽  
Ravi Varala ◽  
Syed Farooq Adil ◽  
Mujeeb Khan ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Data ◽  
Multicomponent Reaction ◽  
Biological Evaluation ◽  
Anhydrous Ethanol ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Metal Free ◽  
Substituted Benzaldehydes

A series of (E)-3-(2-((5-(benzylideneamino)-1,3,4-thiadiazol-2-yl)thio) acetyl)-2H-chromen-2-one and its derivatives (4a-h) have been obtained using a one-pot multicomponent reaction with good yields. The compounds have been synthesized from 3-(2-bromoacetyl)chromen-2-ones (1), 5-amino-1,3,4-thiadiazole-2-thiol (2), and substituted benzaldehydes (3) in anhydrous ethanol and conc. H2SO4. Subsequently, all the synthesized compounds have been screened for their antimicrobial activity and characterized by analytical and spectral data.

Intramolecular radical non-reductive alkylation of ketones via transient enamines

2016 ◽  
Vol 52 (97) ◽  
pp. 14031-14034 ◽  
Author(s):  
Faïza Diaba ◽  
Juan A. Montiel ◽  
Josep Bonjoch
Keyword(s):  
Microwave Activation ◽  
Reductive Alkylation ◽  
One Pot ◽  
Radical Procedure

A five-minute one-pot cyclization of dichloro-acetamide-tethered ketones was achieved under microwave activation through a radical procedure involving a transient enamine.

scholarly journals Synthesis of Substituted Benzaldehydes via a Two-Step, One-Pot Reduction/Cross-Coupling Procedure

2019 ◽  
Vol 21 (11) ◽  
pp. 4087-4091 ◽  
Author(s):  
Dorus Heijnen ◽  
Hugo Helbert ◽  
Gert Luurtsema ◽  
Philip H. Elsinga ◽  
Ben L. Feringa
Keyword(s):  
Cross Coupling ◽  
One Pot ◽  
Coupling Procedure ◽  
Substituted Benzaldehydes

Dry-media one-pot syntheses of fluorinated-2,3-dihydro-1,5-benzothiazepines under microwave activation

2002 ◽  
Vol 4 (6) ◽  
pp. 599-602 ◽  
Author(s):  
Anshu Dandia ◽  
Meha Sati ◽  
Andr?? Loupy
Keyword(s):  
Microwave Activation ◽  
One Pot
Sign in / Sign up

Export Citation Format

Share Document