Supercritical fluid extraction vs conventional extraction of myrtle leaves and berries: Comparison of antioxidant activity and identification of bioactive compounds

2016 ◽  
Vol 113 ◽  
pp. 1-9 ◽  
Author(s):  
Paula Pereira ◽  
Maria-João Cebola ◽  
M. Conceição Oliveira ◽  
M. Gabriela Bernardo-Gil
Keyword(s):  
Antioxidant Activity ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Bioactive Compounds ◽  
Fluid Extraction ◽  
Conventional Extraction

scholarly journals Application of Box-Behnken Design and Desirability Function for Green Prospection of Bioactive Compounds from Isochrysis galbana

2020 ◽  
Vol 10 (8) ◽  
pp. 2789 ◽  
Author(s):  
Mari Carmen Ruiz-Domínguez ◽  
Pedro Cerezal ◽  
Francisca Salinas ◽  
Elena Medina ◽  
Gabriel Renato-Castro
Keyword(s):  
Antioxidant Activity ◽  
Fatty Acid ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Bioactive Compounds ◽  
Environmental Concern ◽  
Desirability Function ◽  
Isochrysis Galbana ◽  
Fluid Extraction ◽  
Box Behnken Design

A microalga, Isochrysis galbana, was chosen in this study for its potent natural antioxidant composition. A broad bioactive compounds spectrum such as carotenoids, fatty acid polyunsaturated (PUFA), and antioxidant activity are described with numerous functional properties. However, most of the optimization of extraction use toxic solvents or consume a lot of it becoming an environmental concern. In this research, a Box-Behnken design with desirability function was used to prospect the bioactive composition by supercritical fluid extraction (SFE) after performing the kinetics curve to obtain the optimal extraction time minimizing operational costs in the process. The parameters studied were: pressure (20–40 MPa), temperature (40–60 °C), and co-solvent (0–8% ethanol) with a CO2 flow rate of 7.2 g/min for 120 min. The response variables evaluated in I. galbana were extraction yield, carotenoids content and recovery, total phenols, antioxidant activity (TEAC method, trolox equivalents antioxidant capacity method), and fatty acid profile and content. In general, improvement in all variables was observed using an increase in ethanol concentration used as a co-solvent (8% v/v ethanol) high pressure (40 MPa), and moderately high temperature (50 °C). The fatty acids profile was rich in polyunsaturated fatty acid (PUFA) primarily linoleic acid (C18:2) and linolenic acid (C18:3). Therefore, I. galbana extracts obtained by supercritical fluid extraction showed relevant functional ingredients for use in food and nutraceutical industries.

scholarly journals Bioactive Compounds Obtained from Polish “Marynka” Hop Variety Using Efficient Two-Step Supercritical Fluid Extraction and Comparison of Their Antibacterial, Cytotoxic, and Anti-Proliferative Activities In Vitro

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2366
Author(s):  
Katarzyna Klimek ◽  
Katarzyna Tyśkiewicz ◽  
Malgorzata Miazga-Karska ◽  
Agnieszka Dębczak ◽  
Edward Rój ◽  
...  
Keyword(s):  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Bioactive Compounds ◽  
Crude Extract ◽  
Normal Skin ◽  
Extraction Methods ◽  
Biological Properties ◽  
Added Value ◽  
Fluid Extraction

Given the health-beneficial properties of compounds from hop, there is still a growing trend towards developing successful extraction methods with the highest yield and also receiving the products with high added value. The aim of this study was to develop efficient extraction method for isolation of bioactive compounds from the Polish “Marynka” hop variety. The modified two-step supercritical fluid extraction allowed to obtain two hop samples, namely crude extract (E1), composed of α-acids, β-acids, and terpene derivatives, as well as pure xanthohumol with higher yield than that of other available methods. The post-extraction residues (R1) were re-extracted in order to obtain extract E2 enriched in xanthohumol. Then, both samples were subjected to investigation of their antibacterial (anti-acne, anti-caries), cytotoxic, and anti-proliferative activities in vitro. It was demonstrated that extract (E1) possessed more beneficial biological properties than xanthohumol. It exhibited not only better antibacterial activity against Gram-positive bacteria strains (MIC, MBC) but also possessed a higher synergistic effect with commercial antibiotics when compared to xanthohumol. Moreover, cell culture experiments revealed that crude extract neither inhibited viability nor divisions of normal skin fibroblasts as strongly as xanthohumol. In turn, calculated selectivity indexes showed that the crude extract had from slightly to significantly better selective anti-proliferative activity towards cancer cells in comparison with xanthohumol.

Chemical profile and antioxidant activity of sage herbal dust extracts obtained by supercritical fluid extraction

2018 ◽  
Vol 120 ◽  
pp. 305-312 ◽  
Author(s):  
Branimir Pavlić ◽  
Oskar Bera ◽  
Nemanja Teslić ◽  
Senka Vidović ◽  
Giuseppina Parpinello ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Chemical Profile ◽  
Fluid Extraction

scholarly journals Optimizing the supercritical fluid extraction process of bioactive compounds from processed tomato skin by-products

2020 ◽  
Vol 40 (3) ◽  
pp. 692-697
Author(s):  
Teresa Maria PELLICANÒ ◽  
Vincenzo SICARI ◽  
Monica Rosa LOIZZO ◽  
Mariarosaria LEPORINI ◽  
Tiziana FALCO ◽  
...  
Keyword(s):  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Bioactive Compounds ◽  
Extraction Process ◽  
Fluid Extraction ◽  
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