A diastereoselective synthesis of 7α-nitromethyl steroid derivative and its use for an efficient synthesis of eplerenone

Steroids ◽  
2012 ◽  
Vol 77 (11) ◽  
pp. 1086-1091 ◽  
Author(s):  
Bin Zhang ◽  
Hongli Chen ◽  
Huanyu Tang ◽  
Huijin Feng ◽  
Yuanchao Li
Keyword(s):  
Diastereoselective Synthesis ◽  
Efficient Synthesis ◽  
Steroid Derivative

Diastereoselective Synthesis of Functionalised Trans-Tetrahydrobenzofuran-4-Ones in an Aqueous Medium by using DABCO as an Efficient Catalyst

2017 ◽  
Vol 41 (11) ◽  
pp. 657-660 ◽  
Author(s):  
Mohammad Reza Salari ◽  
Mohammad H. Mosslemin ◽  
Alireza Hassanabadi
Keyword(s):  
Aqueous Medium ◽  
High Purity ◽  
Reaction Times ◽  
Diastereoselective Synthesis ◽  
Efficient Synthesis ◽  
One Pot ◽  
Efficient Catalyst ◽  
Pyridinium Bromide ◽  
Work Up

A one-pot, efficient synthesis of 11 novel 2,3-diacylated trans-tetrahydrobenzofuran-4-one derivatives has been achieved via a three-component condensation of a N-(4-halophenacyl)-pyridinium bromide, a cyclic 1,3-diketone such as 5,5-dimethyl-1,3-cyclohexanedione (dimedone) or cyclohexane-1,3-dione and an arylglyoxal in the presence of catalytic amounts of 1,4-diaza-bicyclo[2.2.2]octane (DABCO) in water under reflux conditions. The attractive features of the method are excellent yields and high purity, short reaction times, easy work-up, and use of an inexpensive and non-toxic catalyst.

scholarly journals Stereocontrolled addition of Grignard reagents to oxa-bridged benzazepines: highly efficient synthesis of functionalized benzazepine scaffolds

RSC Advances ◽  
2020 ◽  
Vol 10 (68) ◽  
pp. 41802-41806
Author(s):  
Yuewei Zhang ◽  
Qingqing Bao ◽  
Ning Zhang ◽  
Shuohang Wang ◽  
Xue Yu
Keyword(s):  
Grignard Reagents ◽  
Diastereoselective Synthesis ◽  
Efficient Synthesis ◽  
Highly Efficient

An efficient and highly diastereoselective synthesis of 2-substituted benzo[b]azepin-5-ol via stereocontrolled addition of Grignard reagents to oxa-bridged benzazepines has been developed.

Diastereoselective synthesis of dispiro[indoline-3,1′-cyclobutane-2′,3″-indolines] via visible light catalyzed cyclodimerization of 3-phenacylideneoxindoles

2016 ◽  
Vol 22 (3) ◽  
Author(s):  
Yan-Hong Jiang ◽  
Ren-Yin Yang ◽  
Jing Sun ◽  
Chao-Guo Yan
Keyword(s):  
Visible Light ◽  
Catalytic Amount ◽  
Diastereoselective Synthesis ◽  
Efficient Synthesis ◽  
Reaction Proceeds

AbstractA simple synthetic protocol was developed for the efficient synthesis of functionalized dispiro[indoline-3,1′-cyclobutane-2′,3″-indolines] with high diastereoselectivity. The reaction proceeds by cyclodimerization reaction of 3-phenacylideneoxindoles in the presence of a catalytic amount of photosensitizer Ru(bpy

scholarly journals Nano γ-Fe2O3-Quinuclidine-Based Catalyst as a Recyclable Organic Base for the Diastereoselective Synthesis of Trans-2,3-Dihydrofuro[3,2-C]Coumarins

2018 ◽  
Vol 42 (8) ◽  
pp. 439-443 ◽  
Author(s):  
Rozita Vatanchian ◽  
Mohammad H. Mosslemin ◽  
Masoumeh Tabatabaee ◽  
Ali Sheibani
Keyword(s):  
Diastereoselective Synthesis ◽  
Organic Base ◽  
Efficient Synthesis ◽  
Pyridinium Bromide

A nano γ-Fe2O3-quinuclidine-based catalyst as a new, magnetically recyclable heterogeneous organic base was synthesised and used in the efficient synthesis of a series of 11 trans-3-aroyl-2-(4-halobenzoyl)-2,3-dihydro-4H-furo[3,2-c]chromen-4-ones by the reaction of N-(2-(4-halobenzoyl)-2-oxoethyl)pyridinium bromide with 4-hydroxycoumarin and an aryl glyoxal. The catalyst was easily isolated from the reaction mixture using a magnetic bar and reused at least 10 times without significant decrease in its activity.

scholarly journals Short and efficient synthesis of fluorinated δ-lactams

2015 ◽  
Vol 13 (3) ◽  
pp. 717-728 ◽  
Author(s):  
Thomas J. Cogswell ◽  
Craig S. Donald ◽  
De-Liang Long ◽  
Rodolfo Marquez
Keyword(s):  
Diastereoselective Synthesis ◽  
Efficient Synthesis

The diastereoselective synthesis of fluorinated δ-lactams.

Sign in / Sign up

Export Citation Format

Share Document