Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis

Stanley J. Tamaki; Yakop Jacobs; Monika Dohse; Alexandra Capela; Jonathan D. Cooper; Michael Reitsma; Dongping He; Robert Tushinski; Pavel V. Belichenko; Ahmad Salehi; William Mobley; Fred H. Gage; Stephen Huhn; Ann S. Tsukamoto; Irving L. Weissman; Nobuko Uchida

doi:10.1016/j.stem.2009.05.022

Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis

Cell Stem Cell ◽

10.1016/j.stem.2009.05.022 ◽

2009 ◽

Vol 5 (3) ◽

pp. 310-319 ◽

Cited By ~ 104

Author(s):

Stanley J. Tamaki ◽

Yakop Jacobs ◽

Monika Dohse ◽

Alexandra Capela ◽

Jonathan D. Cooper ◽

...

Keyword(s):

Stem Cells ◽

Central Nervous System ◽

Nervous System ◽

Mouse Model ◽

Neuronal Ceroid Lipofuscinosis ◽

Host Cells ◽

Human Central Nervous System ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis

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A murine model of infantile neuronal ceroid lipofuscinosis - Ultrastructural evaluation of storage in the central nervous system and viscera

Pediatric and Developmental Pathology ◽

10.2350/07-03-0242 ◽

2006 ◽

Vol preprint (2007) ◽

pp. 1

Author(s):

Nancy Galvin ◽

Carole Vogler ◽

Beth Levy ◽

Attila Kovacs ◽

Megan Griffey ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Murine Model ◽

Neuronal Ceroid Lipofuscinosis ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis ◽

The Central Nervous System

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Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system

Gene Therapy ◽

10.1038/sj.gt.3301843 ◽

2003 ◽

Vol 10 (1) ◽

pp. 34-42 ◽

Cited By ~ 49

Author(s):

R E Haskell ◽

S M Hughes ◽

J A Chiorini ◽

J M Alisky ◽

B L Davidson

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Neuronal Ceroid Lipofuscinosis ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis ◽

Mouse Central Nervous System

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Safety of Direct Administration of AAV2CUhCLN2, a Candidate Treatment for the Central Nervous System Manifestations of Late Infantile Neuronal Ceroid Lipofuscinosis, to the Brain of Rats and Nonhuman Primates

Human Gene Therapy ◽

10.1089/hum.2005.16.1484 ◽

2005 ◽

Vol 16 (12) ◽

pp. 1484-1503 ◽

Cited By ~ 40

Author(s):

Neil R. Hackett ◽

D. Eugene Redmond ◽

Dolan Sondhi ◽

E. Lela Giannaris ◽

Elizabeth Vassallo ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Nonhuman Primates ◽

Neuronal Ceroid Lipofuscinosis ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis ◽

The Central Nervous System ◽

Direct Administration ◽

The Brain

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Safety of Direct Administration of AAV2CUhCLN2, a Candidate Treatment for the Central Nervous System Manifestations of Late Infantile Neuronal Ceroid Lipofuscinosis, to the Brain of Rats and Nonhuman Primates

Human Gene Therapy ◽

10.1089/hum.2005.16.ft-151 ◽

2005 ◽

Vol 0 (0) ◽

pp. 051201064428001

Author(s):

Neil R. Hackett ◽

D. Eugene Redmond ◽

Dolan Sondhi ◽

E. Lela Giannaris ◽

Elizabeth Vassallo ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Nonhuman Primates ◽

Neuronal Ceroid Lipofuscinosis ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis ◽

The Central Nervous System ◽

Direct Administration ◽

The Brain

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A Murine Model of Infantile Neuronal Ceroid Lipofuscinosis—Ultrastructural Evaluation of Storage in the Central Nervous System and Viscera

Pediatric and Developmental Pathology ◽

10.2350/07-03-0242.1 ◽

2008 ◽

Vol 11 (3) ◽

pp. 185-192 ◽

Cited By ~ 23

Author(s):

Nancy Galvin ◽

Carole Vogler ◽

Beth Levy ◽

Attila Kovacs ◽

Megan Griffey ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Murine Model ◽

Neuronal Ceroid Lipofuscinosis ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis ◽

The Central Nervous System

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218. Gene Therapy and Enzyme Replacement in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

Molecular Therapy ◽

10.1016/j.ymthe.2006.08.243 ◽

2006 ◽

Vol 13 ◽

pp. S84

Author(s):

Michael Chang ◽

David Sleat ◽

Seng Cheng ◽

Marco Passini ◽

Peter Lobel ◽

...

Keyword(s):

Gene Therapy ◽

Mouse Model ◽

Neuronal Ceroid Lipofuscinosis ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Enzyme Replacement ◽

Ceroid Lipofuscinosis

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Transplantation of human central nervous system stem cells - neuroprotection in retinal degeneration

European Journal of Neuroscience ◽

10.1111/j.1460-9568.2011.07970.x ◽

2012 ◽

Vol 35 (3) ◽

pp. 468-477 ◽

Cited By ~ 83

Author(s):

Trevor J. McGill ◽

Benjamin Cottam ◽

Bin Lu ◽

Shaomei Wang ◽

Sergej Girman ◽

...

Keyword(s):

Stem Cells ◽

Central Nervous System ◽

Nervous System ◽

Retinal Degeneration ◽

Human Central Nervous System

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Juvenile neuronal ceroid lipofuscinosis (JNCL) is associated with aberrant glial activation in the central nervous system

Molecular Genetics and Metabolism ◽

10.1016/j.ymgme.2012.11.127 ◽

2013 ◽

Vol 108 (2) ◽

pp. S53

Author(s):

Tammy Kielian ◽

Maria Burkovetskaya ◽

Nikolay Karpuk ◽

Juan Xiong

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Neuronal Ceroid Lipofuscinosis ◽

Glial Activation ◽

Juvenile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis ◽

The Central Nervous System

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Profound loss of GABAergic interneurons in the PPT1 knockout mouse model of infantile neuronal ceroid lipofuscinosis

Neuropathology and Applied Neurobiology ◽

10.1046/j.1365-2990.2002.39286_29.x ◽

2002 ◽

Vol 28 (2) ◽

pp. 158-159 ◽

Cited By ~ 7

Author(s):

J. D. Cooper ◽

P. Gupta ◽

E. Bible ◽

S. Hofmann ◽

P. Lantos) ◽

...

Keyword(s):

Mouse Model ◽

Knockout Mouse ◽

Neuronal Ceroid Lipofuscinosis ◽

Gabaergic Interneurons ◽

Knockout Mouse Model ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis

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Development of a Disease Model for Late-Infantile Neuronal Ceroid Lipofuscinosis Using Patient Specific Induced Pluripotent Stem Cells

Molecular Genetics and Metabolism ◽

10.1016/j.ymgme.2011.11.157 ◽

2012 ◽

Vol 105 (2) ◽

pp. S59-S60

Author(s):

Andrzej Swistowski ◽

Magali Richard ◽

Guadalupe Sierra ◽

Michael Vellard

Keyword(s):

Stem Cells ◽

Induced Pluripotent Stem Cells ◽

Pluripotent Stem Cells ◽

Neuronal Ceroid Lipofuscinosis ◽

Disease Model ◽

Patient Specific ◽

Infantile Neuronal Ceroid Lipofuscinosis ◽

Ceroid Lipofuscinosis ◽

Induced Pluripotent

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