The influence of subgroup diagnosis on radiographic and clinical outcomes after lumbar fusion for degenerative disc disorders revisited: a systematic review of the literature

2017 ◽  
Vol 17 (1) ◽  
pp. 143-149 ◽  
Author(s):  
Amandeep Bhalla ◽  
Andrew J. Schoenfeld ◽  
Jaiben George ◽  
Michael Moghimi ◽  
Christopher M. Bono
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Lumbar Fusion ◽  
Review Of The Literature ◽  
Degenerative Disc

scholarly journals Survivorship and clinical outcomes of proximal femoral replacement in non-neoplastic primary and revision total hip arthroplasty: a systematic review

2021 ◽  
Vol 22 (S2) ◽  
Author(s):  
Fabio Mancino ◽  
Vincenzo Di Matteo ◽  
Fabrizio Mocini ◽  
Giorgio Cacciola ◽  
Giuseppe Malerba ◽  
...  
Keyword(s):  
Systematic Review ◽  
Total Hip Arthroplasty ◽  
Bone Loss ◽  
Clinical Outcomes ◽  
Hip Arthroplasty ◽  
Complication Rate ◽  
Reoperation Rate ◽  
Revision Total Hip Arthroplasty ◽  
Femoral Bone ◽  
Review Of The Literature

Abstract Background Several studies have evaluated the survivorship and clinical outcomes of proximal femoral replacement (PFR) in complex primary and revision total hip arthroplasty with severe proximal femoral bone loss; however, there remains no consensus on the overall performance of this implant. We therefore performed a systematic review of the literature in order to examine survivorship and complication rates of PFR usage. Methods A systematic review of the literature according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was performed. A comprehensive search of PubMed, MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews was conducted for English articles using various combinations of keywords. Results In all, 18 articles met the inclusion criteria. A total of 578 PFR were implanted. The all-cause reoperation-free survivorship was 76.6%. The overall complication rate was 27.2%. Dislocation was the most common complication observed and the most frequent reason for reoperation with an incidence of 12.8 and 7.6%, respectively. Infection after PFR had an incidence of 7.6% and a reoperation rate of 6.4%. The reoperation rate for aseptic loosening of the implant was 5.9%. Overall, patients had improved outcomes as documented by postoperative hip scores. Conclusion PFR usage have a relatively high complication rate, however, it remains an efficacious treatment option in elderly patients with osteoporotic bone affected by severe proximal femoral bone loss. Modular designs have shown reduced dislocations rate and higher survivorship free from dislocation. However, PFR should only be used as salvage procedure when no other reconstruction options are available.

Clinical Outcomes in Ring Avulsion Fingers and Systematic Review of the Literature

2020 ◽  
Vol 85 (6) ◽  
pp. 631-637
Author(s):  
Jorge Bonastre Juliá ◽  
Ángela Ojeda Regidor ◽  
Jose Martínez-Méndez ◽  
Luis Landín ◽  
Shirin Zarbakhsh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Review Of The Literature ◽  
Ring Avulsion

scholarly journals Efficacy and safety of dynamic stabilization for patients with degenerative disc, spinal stenosis and low back pain: a systematic review of randomized controlled clinical trials

2010 ◽  
Vol 9 (3) ◽  
pp. 315-321
Author(s):  
Gustavo Carriço de Oliveira ◽  
Pedro Henrique Lacombe Antoneli
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Low Back Pain ◽  
Back Pain ◽  
Spinal Stenosis ◽  
Low Back ◽  
Efficacy And Safety ◽  
Review Of The Literature ◽  
Degenerative Disc ◽  
Randomized Controlled

STUDY DESIGN: Systematic review of the literature. OBJECTIVE: To perform a systematic review of the literature to organize, critical appraisal and select the best evidence available about the efficacy and safety of non-fusion fixation and its potential use for patients with degenerative disc, spinal stenosis and low back pain. SUMMARY OF BACKGROUND DATA: Recent reports have increased debate about the role of dynamic stabilization in the treatment of chronic back pain associated with lumbar disc degeneration and spinal stenosis. We conducted a systematic review of randomized trials through a more sensitivity search strategy and rigorous criteria applied for the type of studies. METHODS: An electronic search was made in the databases of the Cochrane Central Register of Controlled Trials, Medline, Embase, and Latin American and Caribbean Health Sciences (Lilacs) extended to November 31, 2008, with no linguistic restrictions. RESULTS: One randomized controlled trial that fulfilled the inclusion criteria described above was included in this review. CONCLUSION: The data included in this review show that the use of non-fusion stabilization could be a suitable alternative to another therapies in well selected patients with spinal stenosis and degenerative disc disease. This review highlighted the need for continued research into the use of non-fusion stabilization in the treatment of spinal disorders. There is an urgency need to conduct randomized clinical trials. Long-term efficacy should be evaluated.

The relationship between waiting time for radiotherapy and clinical outcomes: A systematic review of the literature

2008 ◽  
Vol 87 (1) ◽  
pp. 3-16 ◽  
Author(s):  
Zheng Chen ◽  
Will King ◽  
Robert Pearcey ◽  
Marc Kerba ◽  
William J. Mackillop
Keyword(s):  
Systematic Review ◽  
Clinical Outcomes ◽  
Waiting Time ◽  
Review Of The Literature ◽  
The Relationship

scholarly journals Advanced image analytics predicting clinical outcomes in patients with colorectal liver metastases: A systematic review of the literature

2021 ◽  
Vol 38 ◽  
pp. 101578
Author(s):  
N.J. Wesdorp ◽  
V.J. van Goor ◽  
R. Kemna ◽  
E.P. Jansma ◽  
J.H.T.M. van Waesberghe ◽  
...  
Keyword(s):  
Systematic Review ◽  
Liver Metastases ◽  
Clinical Outcomes ◽  
Colorectal Liver Metastases ◽  
Review Of The Literature

scholarly journals Diabetes and Prediabetes in Children With Cystic Fibrosis: A Systematic Review of the Literature and Recommendations of the Italian Society for Pediatric Endocrinology and Diabetes (ISPED)

2021 ◽  
Vol 12 ◽  
Author(s):  
Enza Mozzillo ◽  
Roberto Franceschi ◽  
Claudia Piona ◽  
Stefano Passanisi ◽  
Alberto Casertano ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cystic Fibrosis ◽  
Clinical Outcomes ◽  
Clinical Course ◽  
Analysis Data ◽  
Italian Society ◽  
Review Of The Literature ◽  
Pediatric Endocrinology ◽  
Complete Evaluation ◽  
Beneficial Effects

Cystic fibrosis related diabetes (CFRD) is a comorbidity of cystic fibrosis (CF) that negatively impacts on its clinical course. Prediabetes is an important predictor of either CFRD development and unfavorable prognosis of CF in both pediatric and adult patients. International guidelines recommend insulin only in case of CFRD diagnosis. Whether early detection and treatment of prediabetes may contribute to improve the clinical course of CF is still debated. A subgroup of pediatric diabetologists of the Italian Society for Pediatric Endocrinology and Diabetology (ISPED) performed a systematic review of the literature based on predefined outcomes: impact of pre-diabetes on clinical outcomes and on the risk of developing CFRD; diagnosis of diabetes and pre-diabetes under 10 years of age; effectiveness of therapy on glycemic control, impact of therapy on pulmonary function and nutritional status. Thirty-one papers were selected for the analysis data presented in these papers were reported in tables sorted by outcomes, including comprehensive evidence grading according to the GRADE approach. Following the grading of the quality of the evidence, the entire ISPED diabetes study group achieved consensus for the Italian recommendations based on both evidence and clinical experience. We concluded that in patients with CF, prediabetes should be carefully considered as it can evolve into CFRD. In patients with CF and prediabetic conditions, after complete evaluation of the OGTT trend, glucometrics, glycemic values measured during pulmonary exacerbations and/or steroid therapy, early initiation of insulin therapy could have beneficial effects on clinical outcomes of patients with CF and prediabetes.

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