Highly sensitive protein functionalized nanostructured hafnium oxide based biosensing platform for non-invasive oral cancer detection

2016 ◽  
Vol 235 ◽  
pp. 1-10 ◽  
Author(s):  
Suveen Kumar ◽  
Saurabh Kumar ◽  
Sachchidanand Tiwari ◽  
Shine Augustine ◽  
Saurabh Srivastava ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Detection ◽  
Hafnium Oxide ◽  
Non Invasive ◽  
Highly Sensitive

Cubic CeO2implanted reduced graphene oxide-based highly sensitive biosensor for non-invasive oral cancer biomarker detection

2018 ◽  
Vol 6 (19) ◽  
pp. 3000-3012 ◽  
Author(s):  
Namrata Pachauri ◽  
Kashyap Dave ◽  
Amit Dinda ◽  
Pratima R. Solanki
Keyword(s):  
Graphene Oxide ◽  
Oral Cancer ◽  
Reduced Graphene Oxide ◽  
Cerium Oxide ◽  
Cancer Biomarker ◽  
Electrochemical Technique ◽  
Biomarker Detection ◽  
Non Invasive ◽  
Reduced Graphene ◽  
Highly Sensitive

Herein, we report a cerium oxide nanocubes (ncCeO2)–reduced graphene oxide (RGO)-based nanocomposite for the detection of oral cancer biomarker, cytokeratin fragment-21-1 (Cyfra-21-1), using the electrochemical technique.

Development of biosensor for non-invasive oral cancer detection

2017 ◽  
Vol 72 ◽  
pp. S138-S139 ◽  
Author(s):  
B.K. Yadav ◽  
S. Kumar ◽  
S. Kumar ◽  
D.C. Doval ◽  
B.D. Malhotra
Keyword(s):  
Oral Cancer ◽  
Cancer Detection ◽  
Non Invasive

scholarly journals Malignancies and Biosensors: A Focus on Oral Cancer Detection through Salivary Biomarkers

Biosensors ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 396
Author(s):  
Riccardo Goldoni ◽  
Alessandra Scolaro ◽  
Elisa Boccalari ◽  
Carolina Dolci ◽  
Antonio Scarano ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cancer Detection ◽  
Point Of Care ◽  
Clinical Problem ◽  
Routine Practice ◽  
Comprehensive Overview ◽  
Non Invasive ◽  
Salivary Biomarkers ◽  
Point Of Care Diagnostics ◽  
Invasive Diagnostics

Oral cancer is among the deadliest types of malignancy due to the late stage at which it is usually diagnosed, leaving the patient with an average five-year survival rate of less than 50%. The booming field of biosensing and point of care diagnostics can, in this regard, play a major role in the early detection of oral cancer. Saliva is gaining interest as an alternative biofluid for non-invasive diagnostics, and many salivary biomarkers of oral cancer have been proposed. While these findings are promising for the application of salivaomics tools in routine practice, studies on larger cohorts are still needed for clinical validation. This review aims to summarize the most recent development in the field of biosensing related to the detection of salivary biomarkers commonly associated with oral cancer. An introduction to oral cancer diagnosis, prognosis and treatment is given to define the clinical problem clearly, then saliva as an alternative biofluid is presented, along with its advantages, disadvantages, and collection procedures. Finally, a brief paragraph on the most promising salivary biomarkers introduces the sensing technologies commonly exploited to detect oral cancer markers in saliva. Hence this review provides a comprehensive overview of both the clinical and technological advantages and challenges associated with oral cancer detection through salivary biomarkers.

A biocompatible serine functionalized nanostructured zirconia based biosensing platform for non-invasive oral cancer detection

RSC Advances ◽  
2016 ◽  
Vol 6 (80) ◽  
pp. 77037-77046 ◽  
Author(s):  
Suveen Kumar ◽  
Jai Gopal Sharma ◽  
Sagar Maji ◽  
Bansi Dhar Malhotra
Keyword(s):  
Oral Cancer ◽  
Cancer Detection ◽  
Non Invasive ◽  
Electrochemical Response

Schematic of captured antigen onto BSA/anti-CYFRA-21-1/serine/nZrO2/ITO immunoelectrode and its electrochemical response.

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