Development of a three-dimensional microfluidic system for long-term tumor spheroid culture

2012 ◽  
Vol 173 ◽  
pp. 908-913 ◽  
Author(s):  
Karina Ziółkowska ◽  
Radosław Kwapiszewski ◽  
Agnieszka Stelmachowska ◽  
Michał Chudy ◽  
Artur Dybko ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Microfluidic System ◽  
Tumor Spheroid ◽  
Spheroid Culture

scholarly journals Effect of amine content and chemistry on long-term, three-dimensional hepatocyte spheroid culture atop aminated elastin-like polypeptide coatings

2016 ◽  
Vol 105 (2) ◽  
pp. 377-388 ◽  
Author(s):  
C. Andrew Weeks ◽  
Bethany Aden ◽  
Junlin Zhang ◽  
Anisha Singh ◽  
Raymond D. Hickey ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Spheroid Culture ◽  
Hepatocyte Spheroid ◽  
Amine Content

Studies of anticancer drug cytotoxicity based on long-term HepG2 spheroid culture in a microfluidic system

2017 ◽  
Vol 38 (8) ◽  
pp. 1206-1216 ◽  
Author(s):  
Agnieszka Zuchowska ◽  
Karina Kwapiszewska ◽  
Michal Chudy ◽  
Artur Dybko ◽  
Zbigniew Brzozka
Keyword(s):  
Anticancer Drug ◽  
Microfluidic System ◽  
Spheroid Culture

A thermo-sensitive chitosan/pectin hydrogel for long-term tumor spheroid culture

2021 ◽  
pp. 118633
Author(s):  
Giulia Morello ◽  
Alessandra Quarta ◽  
Antonio Gaballo ◽  
Lorenzo Moroni ◽  
Giuseppe Gigli ◽  
...  
Keyword(s):  
Tumor Spheroid ◽  
Spheroid Culture

Alginate core-shell beads for simplified three-dimensional tumor spheroid culture and drug screening

2015 ◽  
Vol 17 (2) ◽  
Author(s):  
Linfen Yu ◽  
Cynthia Ni ◽  
Samantha M. Grist ◽  
Carmen Bayly ◽  
Karen C. Cheung
Keyword(s):  
Drug Screening ◽  
Three Dimensional ◽  
Core Shell ◽  
Tumor Spheroid ◽  
Spheroid Culture ◽  
Shell Beads

Practical electron tomography

1995 ◽  
Vol 53 ◽  
pp. 742-743
Author(s):  
C.L. Woodcock
Keyword(s):  
Electron Tomography ◽  
Tomographic Reconstruction ◽  
Three Dimensional ◽  
3D Shape ◽  
Computational Resources ◽  
Shape Of Particles

Despite the potential of the technique, electron tomography has yet to be widely used by biologists. This is in part related to the rather daunting list of equipment and expertise that are required. Thanks to continuing advances in theory and instrumentation, tomography is now more feasible for the non-specialist. One barrier that has essentially disappeared is the expense of computational resources. In view of this progress, it is time to give more attention to practical issues that need to be considered when embarking on a tomographic project. The following recommendations and comments are derived from experience gained during two long-term collaborative projects.Tomographic reconstruction results in a three dimensional description of an individual EM specimen, most commonly a section, and is therefore applicable to problems in which ultrastructural details within the thickness of the specimen are obscured in single micrographs. Information that can be recovered using tomography includes the 3D shape of particles, and the arrangement and dispostion of overlapping fibrous and membranous structures.

Custom Presurgical Planning for Midfacial Reconstruction

2020 ◽  
Vol 36 (06) ◽  
pp. 696-702
Author(s):  
Nolan B. Seim ◽  
Enver Ozer ◽  
Sasha Valentin ◽  
Amit Agrawal ◽  
Mead VanPutten ◽  
...  
Keyword(s):  
Multidisciplinary Approach ◽  
Functional Performance ◽  
Three Dimensional ◽  
Free Tissue Transfer ◽  
Long Term Effects ◽  
Presurgical Planning ◽  
Dental Rehabilitation ◽  
Midface Reconstruction ◽  
Reconstructive Algorithm

AbstractResection and reconstruction of midface involve complex ablative and reconstructive tools in head and oncology and maxillofacial prosthodontics. This region is extraordinarily important for long-term aesthetic and functional performance. From a reconstructive standpoint, this region has always been known to present challenges to a reconstructive surgeon due to the complex three-dimensional anatomy, the variable defects created, combination of the medical and dental functionalities, and the distance from reliable donor vessels for free tissue transfer. Another challenge one faces is the unique features of each individual resection defect as well as individual patient factors making each preoperative planning session and reconstruction unique. Understanding the long-term effects on speech, swallowing, and vision, one should routinely utilize a multidisciplinary approach to resection and reconstruction, including head and neck reconstructive surgeons, prosthodontists, speech language pathologists, oculoplastic surgeons, dentists, and/or craniofacial teams as indicated and with each practice pattern. With this in mind, we present our planning and reconstructive algorithm in midface reconstruction, including a dedicated focus on dental rehabilitation via custom presurgical planning.

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