Postmortem diagnosis of aspermatogenesis and hypospermatogenesis in the Nigerian Sahel goat by testicular and epididymal sperm cytometry

2016 ◽  
Vol 144 ◽  
pp. 35-40
Author(s):  
Y. Abba ◽  
I.O. Igbokwe
2021 ◽  
Vol 548 ◽  
pp. 7-13
Author(s):  
Zongzhuang Wen ◽  
Dongyue Liu ◽  
Haixia Zhu ◽  
Xiaoyang Sun ◽  
Yu Xiao ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1155
Author(s):  
Meihui Tian ◽  
Zhipeng Cao ◽  
Hao Pang

The prevention and diagnosis of sudden cardiac death (SCD) are among the most important keystones and challenges in clinical and forensic practice. However, the diagnostic value of the current biomarkers remains unresolved issues. Therefore, novel diagnostic biomarkers are urgently required to identify patients with early-stage cardiovascular diseases (CVD), and to assist in the postmortem diagnosis of SCD cases without typical cardiac damage. An increasing number of studies show that circular RNAs (circRNAs) have stable expressions in myocardial tissue, and their time- and tissue-specific expression levels might reflect the pathophysiological status of the heart, which makes them potential CVD biomarkers. In this article, we briefly introduced the biogenesis and functional characteristics of circRNAs. Moreover, we described the roles of circRNAs in multiple SCD-related diseases, including coronary artery disease (CAD), myocardial ischemia or infarction, arrhythmia, cardiomyopathy, and myocarditis, and discussed the application prospects and challenges of circRNAs as a novel biomarker in the clinical and forensic diagnosis of SCD.


Animals ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 80
Author(s):  
Xin Li ◽  
Chenying Duan ◽  
Ruyi Li ◽  
Dong Wang

To reduce subfertility caused by low semen quality and provide theoretical guidance for the eradication of human male infertility, we sequenced the bovine transcriptomes of round, elongated spermatids and epididymal sperms. The differential analysis was carried out with the reference of the mouse transcriptome, and the homology trends of gene expression to the mouse were also analysed. First, to explore the physiological mechanism of spermiogenesis that profoundly affects semen quality, homological trends of differential genes were compared during spermiogenesis in dairy cattle and mice. Next, Gene Ontology (GO), Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathway enrichment, protein–protein interaction network (PPI network), and bioinformatics analyses were performed to uncover the regulation network of acrosome formation during the transition from round to elongated spermatids. In addition, processes that regulate gene expression during spermiogenesis from elongated spermatid to epididymal sperm, such as ubiquitination, acetylation, deacetylation, and glycosylation, and the functional ART3 gene may play important roles during spermiogenesis. Therefore, its localisation in the seminiferous tubules and epididymal sperm were investigated using immunofluorescent analysis, and its structure and function were also predicted. Our findings provide a deeper understanding of the process of spermiogenesis, which involves acrosome formation, histone replacement, and the fine regulation of gene expression.


Cryobiology ◽  
2021 ◽  
Author(s):  
Samara Sandy Jeronimo Moreira ◽  
Andreia Maria da Silva ◽  
Ana Liza Paz Souza ◽  
Erica Camila Gurgel Praxedes ◽  
João Batista Freire de Souza Junior ◽  
...  

Andrology ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 706-718 ◽  
Author(s):  
Nushin Naderi ◽  
Manouchehr Souri ◽  
Mohammad Hossein Nasr Esfahani ◽  
Mehdi Hajian ◽  
Nima Tanhaei Vash
Keyword(s):  

2012 ◽  
Vol 87 (4) ◽  
Author(s):  
Olivier D'Amours ◽  
Gilles Frenette ◽  
Louis-Jean Bordeleau ◽  
Nancy Allard ◽  
Pierre Leclerc ◽  
...  

Science ◽  
1983 ◽  
Vol 219 (4587) ◽  
pp. 989-991 ◽  
Author(s):  
D. Mukherjee ◽  
A. Agrawal ◽  
R Manjunath ◽  
A. Mukherjee
Keyword(s):  

2013 ◽  
Vol 387 (1-2) ◽  
pp. 113-121 ◽  
Author(s):  
Subir K. Nagdas ◽  
Teresa Buchanan ◽  
Samir Raychoudhury
Keyword(s):  

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