Serum vitamin A and vitamin E concentrations after parenteral vitamin A administration in sheep

2013 ◽  
Vol 109 (1) ◽  
pp. 28-30 ◽  
Author(s):  
A.T. Koutsoumpas ◽  
N.D. Giadinis ◽  
S.Q. Lafi ◽  
E.J. Petridou ◽  
M.-A. Karatzia ◽  
...  
Keyword(s):  
1991 ◽  
Vol 23 (4) ◽  
pp. 399-405 ◽  
Author(s):  
M. Mydlík ◽  
K. Derzsiová ◽  
M. Brátová ◽  
Š. Havriš

2020 ◽  
Vol 8 ◽  
pp. 205031212094053
Author(s):  
Md. Mustafa Kamal ◽  
Farina Aziz ◽  
Md. Rabiul Islam ◽  
Monira Ahsan ◽  
Sheikh Nazrul Islam

Introduction: Acute respiratory infection is a major cause of death for under-5 children in Bangladesh. We aimed to analyze the effect of immunonutritional status, healthcare factors, and lifestyle on the incidence of acute respiratory infection among under-5 children taking individual-level and contextual-level risk factors into consideration. Methods: This study recruited 200 children suffering from acute respiratory infection and 100 healthy controls matched by age, sex, and sociodemographic profile. Serum antioxidant vitamin A (retinol), vitamin C (ascorbic acid), and vitamin E (α-tocopherol) were assessed along with the impact of vaccination, socioeconomic factors, and Z-score on the incidence of acute respiratory infection. Results: Serum antioxidant vitamins were significantly lower in the acute respiratory infection children compared to the non–acute respiratory infection group. Vitamin A was found to be significantly high in acute respiratory infection children who were breastfed for more than 1 year. Vitamin E levels were found to be significantly higher in the acute respiratory infection children who were immunized. Compared to the children living in tin-shed house or huts, serum vitamin E level increased in those acute respiratory infection children who resided in apartments. Vitamin A level was significantly high in those acute respiratory infection children whose height-for-age was −2 SD and above ( Z-score), and vitamin C levels were also significantly high in those acute respiratory infection children whose weight-for-height was −2 SD and below ( Z-score). Conclusion: Deficiencies of antioxidant vitamins along with healthcare and lifestyle factors have a significant influence on the incidence of acute respiratory infection among under-5 children in Bangladesh.


1996 ◽  
Vol 13 (05) ◽  
pp. 287-291 ◽  
Author(s):  
Shahed Ziari ◽  
Veronica Mireles ◽  
Cynthia Cantu ◽  
Miguel Cervantes ◽  
Audu Idrisa ◽  
...  

1994 ◽  
Vol 87 (5) ◽  
pp. 505-511 ◽  
Author(s):  
Timothy M. E. Davis ◽  
Tran Quang Binh ◽  
Phan Thi Danh ◽  
John R. Dyer ◽  
Andrew St John ◽  
...  

1. To assess the association between vitamin A, vitamin E and the clinical course of severe malaria, serial morning blood samples were taken from 24 Vietnamese patients, aged 18–62 years, receiving intensive treatment for complicated Plasmodium falciparum infections. A single fasting blood sample was also taken from 10 control subjects aged 22–45 years. Serum retinol, carotene and vitamin E concentrations were measured by h.p.l.c. 2. Admission serum retinol concentration was depressed relative to that of the control subjects (0.69 ± 0.35 versus 1.86 ± 0.41μmol/l mean ± SD, P < 0.001) and correlated inversely with indices of hepatic function, but positively with the simultaneous serum creatinine concentration (P < 0.05). During the first week of treatment, serum retinol concentration increased in parallel with improving liver function, whereas serum creatinine concentration remained elevated in the majority of patients. Serum α- and β-carotene concentrations remained depressed throughout. 3. Serum vitamin E concentration, corrected for total serum cholesterol concentration in the form of a ratio, was also depressed at presentation (3.1 ± 1.8×103 versus 4.2 ± 0.8×103 in control subjects; P < 0.05), but tended to be higher than the control value at the time of discharge (0.1 > P > 0.05); there was a significant correlation between admission ratio and parasite clearance time (P = 0.04). 4. On the basis of this and previous studies, vitamin A replacement could be considered in selected severely ill patients without renal impairment. As found previously in animal models, depressed vitamin E levels may have a beneficial effect on the course of malarial infection.


2008 ◽  
Vol 7 ◽  
pp. S93
Author(s):  
S. Stezowska ◽  
S. Drzymala-Czyz ◽  
A. Lisowska ◽  
A. Popiel ◽  
W. Cichy ◽  
...  

Author(s):  
Marjan Sohrabi ◽  
Mahmoud Djalali ◽  
Mohammad Hassan Javanbakht ◽  
Niloofar Shekoohi ◽  
Abed Ghavami ◽  
...  

Background: Cigarette smoking is associated with changes in blood concentrations of some antioxidant vitamins. This study aimed to determine the association of cigarette smoking with serum concentrations of vitamins A and E in men. Methods: This was a case-control study, in which the participants were 80 male smokers and 84 male nonsmokers (age range: 20-60 years). Data on dietary intake, health status, smoking habits, anthropometric characteristics, and vitamin levels were compared between cases and controls. Results: Smokers had significantly lower concentrations of serum vitamin E (p = 0.001) and vitamin A (p = 0.013) compared with nonsmokers. However, serum vitamin E to cholesterol ratio was not significantly different between smokers and nonsmokers. Moreover, the highest circulating concentrations of vitamin E was observed in smokers who smoked ≤9 cigarettes per day (p < 0.03), while and the lowest vitamin E was seen in men smoking ≥20 cigarettes per day. Conclusion: The results of this study identified that cigarette smoking is associated with lower levels of serum vitamin E and vitamin A, although it was not associated with vitamin E to cholesterol ratio.


PEDIATRICS ◽  
1985 ◽  
Vol 76 (5) ◽  
pp. 857-857
Author(s):  
BERNARD RUDENSKY ◽  
MEYER ISACSOHN ◽  
ARTHUR I. EIDELMAN

To the Editor.— The pros and cons of vitamin E therapy for premature infants have been quite extensively written about during the past year, especially in Pediatrics.1-4 We were interested in the report of Johnson et al,5 showing increased incidence of sepsis and necrotizing enterocolitis in neonates with elevated serum vitamin E levels. Major et a16 reported that vitamin A inhibited complement-induced hemolysis of sensitized erythrocytes, at concentrations similar to those for vitamin E, implicated by Johnson et al as resulting in increased sepsis rates.


2008 ◽  
Vol 92 (2) ◽  
pp. 220-220
Author(s):  
R. C. Hill ◽  
K. Haynes ◽  
K. C. Scott ◽  
S. J. Tucker ◽  
J. K. Levy ◽  
...  
Keyword(s):  

2020 ◽  
Vol 11 (1) ◽  
pp. 56-62
Author(s):  
Sadegh Piran ◽  
Sahar Sarmasti ◽  
Mohammad Shabani ◽  
Naser Kakavandi ◽  
Bita Hosseni ◽  
...  

Background &Aims: It is well-known that the coronary artery stenosis is related to lipid profile. This is a descriptive cross-sectional study to investigate the relationship between the serum fat-soluble vitamins (A, E and D), circulating proprotein convertase subtilisin/kexin type 9 (PCSK9), and lipid profile in the study population. Methods: A total of 120 overweight subjects were participated in this study. The circulating PCSK9 and vitamin D were measured by ELISA technique. The serum vitamin A and vitamin E amounts were simultaneously measured by the HPLC method. The Serum Small Dense LDLCholesterol (sdLDL-C) values were evaluated using heparin-Mg2+ precipitation technique. The lipid profile was measured by routine laboratory techniques. Results: The serum vitamin E values correlated significantly to vitamin A (r= 0.47, P= 0.0001), VLDL-C (r= 0.30, P= 0.002), total cholesterol (r= 0.309, P= 0.001), PCSK9 (r= 0.233, P= 0.01) and total triglyceride (r= 0.61, P= 0.0001) values. The circulating PCSK9 values correlated significantly to LDL-C (r= 0.17, P= 0.05) and total cholesterol (r= 0.23, P= 0.009) values. However, there were not correlations between the levels of serum D and A vitamins, the serum LDL-C, sdLDL-C and total cholesterol values. Conclusion: The data showed the correlations between serum vitamin E and PCSK9-related LDLC values lower than the normal range. Furthermore, the results suggested a nutritional need on the patents considering supplementation or fortification of vitamin E for the overweight subjects with higher LDL-C levels.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 452.2-453
Author(s):  
Y. Kim ◽  
G. T. Kim ◽  
J. Kang

Background:Hyperuricemia is an important risk factor for gout as well as hypertension, type 2 diabetes and renal impairment. Although previous studies investigated the association of questionnaire-based micronutrient intake with serum uric acid levels, limited data on serum micronutrients levels in relation to the risk of hyperuricemia especially in Asian population.Objectives:This study aimed to evaluate the association of serum vitamin A, vitamin E and folate level with hyperuricemia in the Korean general population.Methods:The present study included 6023 participants (2722 men and 3301 women) aged ≥19 years with available data on serum vitamin A, vitamin E, folate and serum uric acid. General characteristics of participants were compared using the Chi-square test and Student’s t test. The association between serum vitamin A, E and folate and serum uric acid levels were evaluated using general linear regression model. Multivariate logistic regression analyses were performed to estimate the effects of these micronutrients on hyperuricemia.Results:Serum uric acid levels were increased from the lowest quintile of vitamin A levels to the highest quintile after adjustment for covariates (Ptrend< 0.001 in both sexes). In addition, dose-dependent relationship was observed between vitamin A levels and the risk of hyperuricemia in fully-adjusted analyses (Ptrend< 0.001 in both sexes). However, neither serum vitamin E nor serum folate was associated with hyperuricemia across analyses models.Conclusion:This study suggested that vitamin A could be a risk factor of hyperuricemia and further studies are warranted to elucidate underlying mechanism of the observed findings.References:[1]Choi, Woo-Joo, et al. “Independent association of serum retinol and β-carotene levels with hyperuricemia: A national population study.”Arthritis care & research64.3 (2012): 389-396.Disclosure of Interests: :None declared


Sign in / Sign up

Export Citation Format

Share Document