scholarly journals Contributions of the Women's Health Initiative to understanding associations between sleep duration, insomnia symptoms, and sleep-disordered breathing across a range of health outcomes in postmenopausal women

Sleep Health ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. 48-59
Author(s):  
Chloe M. Beverly Hery ◽  
Lauren Hale ◽  
Michelle J. Naughton
Keyword(s):  
Health Outcomes ◽  
Women's Health ◽  
Postmenopausal Women ◽  
Sleep Duration ◽  
Sleep Disordered Breathing ◽  
Women's Health Initiative ◽  
Health Initiative ◽  
Insomnia Symptoms ◽  
The Women’S Health Initiative ◽  
Disordered Breathing

scholarly journals A Cross-Sectional Analysis of Telomere Length and Sleep in the Women’s Health Initiative

2019 ◽  
Vol 188 (9) ◽  
pp. 1616-1626 ◽  
Author(s):  
Laurie Grieshober ◽  
Jean Wactawski-Wende ◽  
Rachael Hageman Blair ◽  
Lina Mu ◽  
Jingmin Liu ◽  
...  
Keyword(s):  
Sleep Disturbance ◽  
Women's Health ◽  
Postmenopausal Women ◽  
Telomere Length ◽  
Sleep Duration ◽  
Entire Sample ◽  
Women's Health Initiative ◽  
Women’S Health Initiative ◽  
Health Initiative ◽  
The Women’S Health Initiative

Abstract Telomere length is a heritable marker of cellular age that is associated with morbidity and mortality. Poor sleep behaviors, which are also associated with adverse health events, may be related to leukocyte telomere length (LTL). We studied a subpopulation of 3,145 postmenopausal women (1,796 European-American (EA) and 1,349 African-American (AA)) enrolled in the Women’s Health Initiative in 1993–1998 with data on Southern blot-measured LTL and self-reported usual sleep duration and sleep disturbance. LTL-sleep associations were analyzed separately for duration and disturbance using weighted and confounder-adjusted linear regression models in the entire sample (AAs + EAs; adjusted for race/ethnicity) and in racial/ethnic strata, since LTL differs by ancestry. After adjustment for covariates, each additional daily hour of sleep beyond 5 hours, approximately, was associated with a 27-base-pair (95% confidence interval (CI): 6, 48) longer LTL in the entire sample. Associations between sleep duration and LTL were strongest among AAs (adjusted β = 37, 95% CI: 4, 70); a similar, nonsignificant association was observed for EAs (adjusted β = 20, 95% CI: −7, 48). Sleep disturbance was not associated with LTL in our study. Our models did not show departure from linearity (quadratic sleep terms: P ≥ 0.55). Our results suggest that longer sleep duration is associated with longer LTL in postmenopausal women.

scholarly journals Sleep Duration and Risk of Liver Cancer in Postmenopausal Women: The Women's Health Initiative Study

2017 ◽  
Vol 26 (12) ◽  
pp. 1270-1277 ◽  
Author(s):  
Kathryn E. Royse ◽  
Hashem B. El-Serag ◽  
Liang Chen ◽  
Donna L. White ◽  
Lauren Hale ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Women’S Health ◽  
Women's Health ◽  
Postmenopausal Women ◽  
Sleep Duration ◽  
Women's Health Initiative ◽  
Women’S Health Initiative ◽  
Health Initiative ◽  
The Women’S Health Initiative
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