The relationship between slow wave activity increase across acute and chronic sleep loss and vigilance impairments

2017 ◽  
Vol 40 ◽  
pp. e210
Author(s):  
A. Maric ◽  
C. Lustenberger ◽  
E. Werth ◽  
C.R. Baumann ◽  
R. Poryazova ◽  
...  
Keyword(s):  
Slow Wave ◽  
Sleep Loss ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Activity Increase ◽  
The Relationship ◽  
Chronic Sleep

scholarly journals Relationship of sleep homeostasis to seizures and cognition in children with focal epilepsy

2020 ◽  
Author(s):  
Maria H Eriksson ◽  
Torsten Baldeweg ◽  
Ronit Pressler ◽  
Stewart G Boyd ◽  
Reto Huber ◽  
...  
Keyword(s):  
Slow Wave ◽  
Focal Epilepsy ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Iq Testing ◽  
Sleep Homeostasis ◽  
Interictal Discharges ◽  
Relationship Of ◽  
The Relationship

AbstractObjectiveSleep disruption and cognitive impairment are important co-morbidities in childhood epilepsy, yet a mechanistic link has not been substantiated. Slow wave activity during sleep and its homeostatic decrease across the night is associated with synaptic renormalisation, and shows maturational changes over the course of childhood. Here, we aimed to investigate the effect of epilepsy on sleep homeostasis in the developing brain.MethodsWe examined the relationship of sleep homeostasis as reflected in slow wave activity to seizures, cognition and behaviour, comparing 22 children (aged 6 to 16 years) with focal epilepsy to 21 age-matched healthy controls. Participants underwent overnight sleep EEG and IQ testing and performed memory consolidation tasks. Their parents completed standard behavioural questionnaires.ResultsChildren with epilepsy had lower slow wave activity at the start of non-rapid eye movement (NREM) sleep, though similar overnight decline and slow wave activity in the final hour of NREM sleep. Both groups displayed an antero-posterior shift in peak slow wave activity overnight, though individual patients showed persistent local increases at scalp locations matching those of focal interictal discharges. Patients who had seizures during their admission had lower early-night slow wave activity, the group without seizures showing similar activity to controls. We found a positive correlation between full scale IQ and early-night slow wave activity in patients but not controls.InterpretationReduced early night slow wave activity in children with focal epilepsies is correlated with lower cognitive ability and more seizures and may reflect a reduction in learning-related synaptic potentiation.

scholarly journals 0321 Increased Slow-Wave Activity Predicts Slower Processing Speed in Toddlers

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A122-A122
Author(s):  
A E Waddle ◽  
S Kurth ◽  
J Harsh ◽  
J M Lassonde ◽  
D Lee ◽  
...  
Keyword(s):  
Reaction Time ◽  
Slow Wave ◽  
Processing Speed ◽  
Cognitive Skills ◽  
Time Course ◽  
Spectral Power ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
The Relationship

Abstract Introduction Slow-wave activity (SWA) shows an inverted U-shaped time course during development. Specifically, maximal SWA undergoes a posteroanterior shift from 2 to 20 years of age, which may reflect cortical maturation. Previously, we showed that greater slow sigma power during sleep predicted faster reaction time in preschool-aged children. To date, little is known about the relationship between SWA and processing speed (PS), a basic fundament underlying complex cognitive skills in early development. Methods This project examined the relationship between SWA and PS in 2.5-3.0-year-old children (n=26, 50% males) via home-based assessments. After a 5-day stabilization sleep schedule, a baseline sleep EEG recording was performed on participants at 4 electrode placements: Fz, Oz, C3, and C4. SWA EEG spectral power was quantified in the 0.75-4.5 Hz rangeduring the first 60 minutes of NREM sleep. PS was obtained as part of a standard cognitive assessment via a computer-based task one hour after waking from a midday nap. Results On average, reaction time (PS) was 2111 ± 08 ms and SWA was 856.4 ± 300.7 µV2/Hz. Increased SWA in the occipital region was predictive of a longer reaction time and therefore slower PS (r = 0.44, p = 0.03). This relationship showed differences between sexes, suggesting that females (r = 0.26, p = 0.07) may show a stronger association between SWA in the occipital brain region and PS than males (r = 0.09, p = 0.33). Conclusion Interestingly, these findings contradict our hypothesis based on previous data with older children indicating that greater SWA was associated with more advanced behavioral and cognitive skills. This discrepancy may reflect the stark individual differences present within this rapidly maturing age group. Support Research support from NIH R01-MH086566 to MKL.

Forebrain rhythm generators influence sympathetic activity in anesthetized cats

1990 ◽  
Vol 259 (3) ◽  
pp. R572-R578
Author(s):  
M. J. Kenney ◽  
G. L. Gebber ◽  
S. M. Barman ◽  
B. Kocsis
Keyword(s):  
Slow Wave ◽  
Coherence Function ◽  
Sympathetic Nerves ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Descending Influences ◽  
Alpha Chloralose ◽  
The Relationship ◽  
Electroencephalogram Eeg ◽  
Renal Sympathetic

Autospectral and coherence analyses were used to study the frequency-domain relationships between frontal-parietal cortical activity [electroencephalogram (EEG)] and the discharges of the interior cardiac and renal sympathetic nerves of baroreceptor-denervated and vagotomized cats anesthetized with either alpha-chloralose or pentobarbital sodium. Delta slow-wave activity in the EEG was correlated to sympathetic nerve discharge (SND) as shown by sharp peaks between 0.5 and 4 Hz in the coherence function. The relationship was stronger in chloralose- than in pentobarbital-anesthetized cats. Coherence of the two signals could be attributed to descending influences of forebrain delta slow-wave generators on sympathetic circuits, since midbrain transection preferentially reduced the power in SND at frequencies that cohered to the EEG before transection. In contrast, the power in the EEG was not reduced by midbrain transection. The relationship between cortical delta slow-wave activity and SND was stronger during than between cortical spindlelike events that lasted 1-3 s and recurred once every 5-10 s. These events were similar to cortical spindles observed during the early stages of sleep and under light barbiturate anesthesia. These observations raise the possibility that the influences of forebrain delta slow-wave generators on SND are gated by thalamic mechanisms normally involved in the sleep-wake cycle.

scholarly journals Why Does Sleep Slow-Wave Activity Increase After Extended Wake? Assessing the Effects of Increased Cortical Firing During Wake and Sleep

2016 ◽  
Vol 36 (49) ◽  
pp. 12436-12447 ◽  
Author(s):  
Alexander V. Rodriguez ◽  
Chadd M. Funk ◽  
Vladyslav V. Vyazovskiy ◽  
Yuval Nir ◽  
Giulio Tononi ◽  
...  
Keyword(s):  
Slow Wave ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Activity Increase

Sa1640 NONINVASIVE MEASUREMENT OF SMALL BOWEL SLOW WAVE ACTIVITY IN NEONATES - A PILOT STUDY

2020 ◽  
Vol 158 (6) ◽  
pp. S-364
Author(s):  
Suseela Somarajan ◽  
Nicole D. Muszynski ◽  
Aurelia s. Monk ◽  
Joseph D. Olson ◽  
Alexandra Russell ◽  
...  
Keyword(s):  
Pilot Study ◽  
Small Bowel ◽  
Slow Wave ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Noninvasive Measurement

Slow Wave Activity Related to Working Memory Maintenance in the N-Back Task

2016 ◽  
Vol 30 (4) ◽  
pp. 141-154 ◽  
Author(s):  
Kira Bailey ◽  
Gregory Mlynarczyk ◽  
Robert West
Keyword(s):  
Working Memory ◽  
Slow Wave ◽  
Time Course ◽  
Relevant Information ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Response Accuracy ◽  
Functional Neuroanatomy ◽  
Stimulus Interval ◽  
Back Task

Abstract. Working memory supports our ability to maintain goal-relevant information that guides cognition in the face of distraction or competing tasks. The N-back task has been widely used in cognitive neuroscience to examine the functional neuroanatomy of working memory. Fewer studies have capitalized on the temporal resolution of event-related brain potentials (ERPs) to examine the time course of neural activity in the N-back task. The primary goal of the current study was to characterize slow wave activity observed in the response-to-stimulus interval in the N-back task that may be related to maintenance of information between trials in the task. In three experiments, we examined the effects of N-back load, interference, and response accuracy on the amplitude of the P3b following stimulus onset and slow wave activity elicited in the response-to-stimulus interval. Consistent with previous research, the amplitude of the P3b decreased as N-back load increased. Slow wave activity over the frontal and posterior regions of the scalp was sensitive to N-back load and was insensitive to interference or response accuracy. Together these findings lead to the suggestion that slow wave activity observed in the response-to-stimulus interval is related to the maintenance of information between trials in the 1-back task.

scholarly journals Electroencephalogram During Sleep in the Cat: Age Effects on Slow-Wave Activity

SLEEP ◽  
1984 ◽  
Vol 7 (4) ◽  
pp. 380-385 ◽  
Author(s):  
S. Scott Bowersox ◽  
Tom Floyd ◽  
William C. Dement
Keyword(s):  
Slow Wave ◽  
Wave Activity ◽  
Age Effects ◽  
Slow Wave Activity
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