P343 Central sleep apnea and central periodic breathing during sleep in acute ischemic stroke

2006 ◽  
Vol 7 ◽  
pp. S62-S63
Author(s):  
Massimiliano M. Siccoli ◽  
Claudio L. Bassetti
Keyword(s):  
Ischemic Stroke ◽  
Sleep Apnea ◽  
Acute Ischemic Stroke ◽  
Central Sleep Apnea ◽  
Periodic Breathing

Adaptive servo-ventilation as treatment of persistent central sleep apnea in post-acute ischemic stroke patients

2014 ◽  
Vol 15 (11) ◽  
pp. 1309-1313 ◽  
Author(s):  
Anne-Kathrin Brill ◽  
Regula Rösti ◽  
Jacqueline Pichler Hefti ◽  
Claudio Bassetti ◽  
Matthias Gugger ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Sleep Apnea ◽  
Acute Ischemic Stroke ◽  
Central Sleep Apnea ◽  
Stroke Patients ◽  
Adaptive Servo Ventilation

Sleep Apnea-Predictor of Functional Outcome in Acute Ischemic Stroke

2019 ◽  
Vol 28 (3) ◽  
pp. 807-814 ◽  
Author(s):  
Radhika Nair ◽  
Kurupath Radhakrishnan ◽  
Aparajita Chatterjee ◽  
Shankar P. Gorthi ◽  
Varsha A. Prabhu
Keyword(s):  
Ischemic Stroke ◽  
Sleep Apnea ◽  
Acute Ischemic Stroke ◽  
Functional Outcome

scholarly journals Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes

2009 ◽  
Vol 107 (3) ◽  
pp. 696-706 ◽  
Author(s):  
Yoseph Mebrate ◽  
Keith Willson ◽  
Charlotte H. Manisty ◽  
Resham Baruah ◽  
Jamil Mayet ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Sleep Apnea ◽  
Time Window ◽  
Central Sleep Apnea ◽  
Periodic Breathing ◽  
Optimal Time ◽  
Optimal Timing ◽  
Ventilatory Control ◽  
Dynamic Therapy ◽  
End Tidal

We examine the potential to treat unstable ventilatory control (seen in periodic breathing, Cheyne-Stokes respiration, and central sleep apnea) with carefully controlled dynamic administration of supplementary CO2, aiming to reduce ventilatory oscillations with minimum increment in mean CO2. We used a standard mathematical model to explore the consequences of phasic CO2 administration, with different timing and dosing algorithms. We found an optimal time window within the ventilation cycle (covering ∼1/6 of the cycle) during which CO2 delivery reduces ventilatory fluctuations by >95%. Outside that time, therapy is dramatically less effective: indeed, for more than two-thirds of the cycle, therapy increases ventilatory fluctuations >30%. Efficiency of stabilizing ventilation improved when the algorithm gave a graded increase in CO2 dose (by controlling its duration or concentration) for more severe periodic breathing. Combining gradations of duration and concentration further increased efficiency of therapy by 22%. The (undesirable) increment in mean end-tidal CO2 caused was 300 times smaller with dynamic therapy than with static therapy, to achieve the same degree of ventilatory stabilization (0.0005 vs. 0.1710 kPa). The increase in average ventilation was also much smaller with dynamic than static therapy (0.005 vs. 2.015 l/min). We conclude that, if administered dynamically, dramatically smaller quantities of CO2 could be used to reduce periodic breathing, with minimal adverse effects. Algorithms adjusting both duration and concentration in real time would achieve this most efficiently. If developed clinically as a therapy for periodic breathing, this would minimize excess acidosis, hyperventilation, and sympathetic overactivation, compared with static treatment.

scholarly journals Supine sleep and positional sleep apnea after acute ischemic stroke and intracerebral hemorrhage

Clinics ◽  
2012 ◽  
Vol 67 (12) ◽  
pp. 1357-1360 ◽  
Author(s):  
MR Camilo ◽  
RM Fernandes ◽  
HH Sander ◽  
F Nobre ◽  
T Santos-Pontelli ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Sleep Apnea ◽  
Intracerebral Hemorrhage ◽  
Acute Ischemic Stroke ◽  
Supine Sleep
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