Notch receptor–ligand binding and activation: Insights from molecular studies

Chandramouli R. Chillakuri; Devon Sheppard; Susan M. Lea; Penny A. Handford

doi:10.1016/j.semcdb.2012.01.009

Notch receptor–ligand binding and activation: Insights from molecular studies

Seminars in Cell and Developmental Biology ◽

10.1016/j.semcdb.2012.01.009 ◽

2012 ◽

Vol 23 (4) ◽

pp. 421-428 ◽

Cited By ~ 100

Author(s):

Chandramouli R. Chillakuri ◽

Devon Sheppard ◽

Susan M. Lea ◽

Penny A. Handford

Keyword(s):

Ligand Binding ◽

Notch Receptor ◽

Receptor Ligand ◽

Molecular Studies

Download Full-text

Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor

Reactome - a curated knowledgebase of biological pathways ◽

10.3180/react_2001.2 ◽

2007 ◽

Vol 21 ◽

Author(s):

B Jassal

Keyword(s):

Ligand Binding ◽

Proteolytic Cleavage ◽

Notch Receptor ◽

Receptor Ligand

Download Full-text

Three-dimensional structure of homodimeric androgen receptor ligand-binding domain

Endocrine Abstracts ◽

10.1530/endoabs.42.il3 ◽

2016 ◽

Author(s):

Eva Estebanez Perpina

Keyword(s):

Androgen Receptor ◽

Ligand Binding ◽

Three Dimensional ◽

Binding Domain ◽

Ligand Binding Domain ◽

Dimensional Structure ◽

Receptor Ligand ◽

Three Dimensional Structure

Download Full-text

Human formyl peptide receptor ligand binding domain(s). Studies using an improved mutagenesis/expression vector reveal a novel mechanism for the regulation of receptor occupancy.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)31671-x ◽

1994 ◽

Vol 269 (36) ◽

pp. 22485-22487

Author(s):

H.D. Perez ◽

L. Vilander ◽

W.H. Andrews ◽

R. Holmes

Keyword(s):

Ligand Binding ◽

Expression Vector ◽

Receptor Occupancy ◽

Binding Domain ◽

Ligand Binding Domain ◽

Formyl Peptide Receptor ◽

Receptor Ligand ◽

Peptide Receptor ◽

Formyl Peptide

Download Full-text

Mechanism of Vitamin D Receptor Ligand-Binding Domain Regulation Studied by gREST Simulations

Journal of Chemical Information and Modeling ◽

10.1021/acs.jcim.1c00534 ◽

2021 ◽

Author(s):

Toru Ekimoto ◽

Takafumi Kudo ◽

Tsutomu Yamane ◽

Mitsunori Ikeguchi

Keyword(s):

Vitamin D ◽

Ligand Binding ◽

Vitamin D Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand

Download Full-text

High Level Production, Characterization and Construct Optimization of the Ionotropic Glutamate Receptor Ligand Binding Core

Tetrahedron ◽

10.1016/s0040-4020(00)00825-5 ◽

2000 ◽

Vol 56 (48) ◽

pp. 9409-9419 ◽

Cited By ~ 2

Author(s):

Guo Qiang Chen ◽

Eric Gouaux

Keyword(s):

Ligand Binding ◽

Glutamate Receptor ◽

Ionotropic Glutamate Receptor ◽

Receptor Ligand ◽

Construct Optimization ◽

Binding Core ◽

High Level ◽

Level Production

Download Full-text

Regulation of endothelial cell and platelet receptor-ligand binding by the 12- and 15-lipoxygenase monohydroxides, 12-, 15-HETE and 13-HODE

Prostaglandins Leukotrienes and Essential Fatty Acids ◽

10.1016/s0952-3278(98)90069-2 ◽

1998 ◽

Vol 58 (5) ◽

pp. 339-346 ◽

Cited By ~ 22

Author(s):

M.R. Buchanan ◽

P. Horsewood ◽

S.J. Brister

Keyword(s):

Endothelial Cell ◽

Ligand Binding ◽

Receptor Ligand ◽

Platelet Receptor

Download Full-text

Identification of a Determinant of Epidermal Growth Factor Receptor Ligand-Binding Specificity Using a Truncated, High-Affinity Form of the Ectodomain

Biochemistry ◽

10.1021/bi010037b ◽

2001 ◽

Vol 40 (30) ◽

pp. 8930-8939 ◽

Cited By ~ 65

Author(s):

Thomas C. Elleman ◽

Teresa Domagala ◽

Neil M. McKern ◽

Maureen Nerrie ◽

Björn Lönnqvist ◽

...

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Ligand Binding ◽

Growth Factor Receptor ◽

Binding Specificity ◽

Receptor Ligand ◽

High Affinity ◽

Epidermal Growth

Download Full-text

Molecular modulators of benzodiazepine receptor ligand binding

International Journal of Quantum Chemistry ◽

10.1002/qua.560360720 ◽

2009 ◽

Vol 36 (S16) ◽

pp. 261-271

Author(s):

H. O. Villar ◽

G. H. Loew

Keyword(s):

Ligand Binding ◽

Benzodiazepine Receptor ◽

Receptor Ligand

Download Full-text

Application of Oestrogen Receptor Ligand Binding Domain to the Generic Isolation of Oestrogens by Receptor Affinity Chromatography

Chromatographia ◽

10.1365/s10337-003-0246-4 ◽

2004 ◽

Vol 59 (S1) ◽

pp. S123-S130 ◽

Cited By ~ 1

Author(s):

M. F. Byford ◽

M. J. Sauer

Keyword(s):

Ligand Binding ◽

Affinity Chromatography ◽

Oestrogen Receptor ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Receptor Affinity

Download Full-text

Simulations of the Estrogen Receptor Ligand-Binding Domain: Affinity of Natural Ligands and Xenoestrogens

Journal of Medicinal Chemistry ◽

10.1021/jm001045d ◽

2000 ◽

Vol 43 (24) ◽

pp. 4594-4605 ◽

Cited By ~ 72

Author(s):

B. Chris Oostenbrink ◽

Jed W. Pitera ◽

Marola M. H. van Lipzig ◽

John H. N. Meerman ◽

Wilfred F. van Gunsteren

Keyword(s):

Estrogen Receptor ◽

Ligand Binding ◽

Binding Domain ◽

Ligand Binding Domain ◽

Receptor Ligand ◽

Natural Ligands ◽

Estrogen Receptor Ligand

Download Full-text