Histone H4 gene expression and morphological changes on shoot apices of strawberry (Fragaria×ananassa Duch.) during floral induction

2006 ◽  
Vol 110 (2) ◽  
pp. 192-197 ◽  
Author(s):  
Takeshi Kurokura ◽  
Yukio Inaba ◽  
Nobuo Sugiyama
Keyword(s):  
Gene Expression ◽  
Morphological Changes ◽  
Floral Induction ◽  
Fragaria Ananassa ◽  
Histone H4 ◽  
Shoot Apices ◽  
Histone H4 Gene

scholarly journals Histone H4 Gene Expression in Shoot Apices Associated with Floral Initiation in Lettuce

2005 ◽  
Vol 74 (2) ◽  
pp. 121-126 ◽  
Author(s):  
O New Lee ◽  
Keisuke Nemoto ◽  
Nobuo Sugiyama
Keyword(s):  
Gene Expression ◽  
Floral Initiation ◽  
Histone H4 ◽  
Shoot Apices ◽  
Histone H4 Gene

scholarly journals HiNF-P Directly Links the Cyclin E/CDK2/p220NPAT Pathway to Histone H4 Gene Regulation at the G1/S Phase Cell Cycle Transition

2005 ◽  
Vol 25 (14) ◽  
pp. 6140-6153 ◽  
Author(s):  
Angela Miele ◽  
Corey D. Braastad ◽  
William F. Holmes ◽  
Partha Mitra ◽  
Ricardo Medina ◽  
...  
Keyword(s):  
Gene Expression ◽  
Phase Transition ◽  
Cell Cycle ◽  
Cyclin E ◽  
S Phase ◽  
Phase Cell ◽  
Genome Replication ◽  
Dependent Manner ◽  
Histone H4 ◽  
Histone H4 Gene

ABSTRACT Genome replication in eukaryotic cells necessitates the stringent coupling of histone biosynthesis with the onset of DNA replication at the G1/S phase transition. A fundamental question is the mechanism that links the restriction (R) point late in G1 with histone gene expression at the onset of S phase. Here we demonstrate that HiNF-P, a transcriptional regulator of replication-dependent histone H4 genes, interacts directly with p220NPAT, a substrate of cyclin E/CDK2, to coactivate histone genes during S phase. HiNF-P and p220 are targeted to, and colocalize at, subnuclear foci (Cajal bodies) in a cell cycle-dependent manner. Genetic or biochemical disruption of the HiNF-P/p220 interaction compromises histone H4 gene activation at the G1/S phase transition and impedes cell cycle progression. Our results show that HiNF-P and p220 form a critical regulatory module that directly links histone H4 gene expression at the G1/S phase transition to the cyclin E/CDK2 signaling pathway at the R point.

Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML

1990 ◽  
Vol 10 (9) ◽  
pp. 4932-4934
Author(s):  
E C Park ◽  
J W Szostak
Keyword(s):  
Gene Expression ◽  
Mating Type ◽  
Point Mutations ◽  
Active Role ◽  
Histone H4 ◽  
Type Locus ◽  
Mating Type Locus ◽  
N Terminus ◽  
Lysine Residues ◽  
Histone H4 Gene

The N-terminal serine and four conserved lysine residues near the N-terminus of yeast histone H4 are acetylated. We found that a mutation that changed the fourth lysine to alanine resulted in specific derepression of the silent mating type locus HML, while mutations that altered the N-terminal serine or the first three lysines had only minor phenotypic effects. Our results support an active role for histone H4 in the silencing of gene expression at this locus.

scholarly journals Point mutations in the yeast histone H4 gene prevent silencing of the silent mating type locus HML.

1990 ◽  
Vol 10 (9) ◽  
pp. 4932-4934 ◽  
Author(s):  
E C Park ◽  
J W Szostak
Keyword(s):  
Gene Expression ◽  
Mating Type ◽  
Point Mutations ◽  
Active Role ◽  
Histone H4 ◽  
Type Locus ◽  
Mating Type Locus ◽  
N Terminus ◽  
Lysine Residues ◽  
Histone H4 Gene

The N-terminal serine and four conserved lysine residues near the N-terminus of yeast histone H4 are acetylated. We found that a mutation that changed the fourth lysine to alanine resulted in specific derepression of the silent mating type locus HML, while mutations that altered the N-terminal serine or the first three lysines had only minor phenotypic effects. Our results support an active role for histone H4 in the silencing of gene expression at this locus.

scholarly journals Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development

Gene ◽  
2011 ◽  
Vol 483 (1-2) ◽  
pp. 1-10 ◽  
Author(s):  
Li-Jun Liu ◽  
Ronglin Xie ◽  
Sadiq Hussain ◽  
Jane B. Lian ◽  
Jaime Rivera-Perez ◽  
...  
Keyword(s):  
Gene Expression ◽  
Transcription Factor ◽  
Functional Coupling ◽  
Histone H4 ◽  
Mouse Development ◽  
Histone H4 Gene

The histone H4 gene of Plasmodium falciparum is developmentally transcribed in asexual parasites

2003 ◽  
Vol 90 (5) ◽  
pp. 387-389 ◽  
Author(s):  
Jude M. Przyborski ◽  
Kathrin Bartels ◽  
Michael Lanzer ◽  
Katherine T. Andrews
Keyword(s):  
Plasmodium Falciparum ◽  
Histone H4 ◽  
Histone H4 Gene

scholarly journals Growth, Development, and Gene Expression in a Persistent Streptococcus gordonii Biofilm

2003 ◽  
Vol 71 (8) ◽  
pp. 4759-4766 ◽  
Author(s):  
Keeta S. Gilmore ◽  
Pravina Srinivas ◽  
Darrin R. Akins ◽  
Kenneth L. Hatter ◽  
Michael S. Gilmore
Keyword(s):  
Gene Expression ◽  
Biofilm Formation ◽  
Bacterial Population ◽  
Morphological Changes ◽  
Expression Patterns ◽  
Nutrient Flux ◽  
Gene Expression Patterns ◽  
Significant Shift ◽  
Streptococcus Gordonii ◽  
Growth Development

ABSTRACT A model for the protracted (30-day) colonization of smooth surfaces by Streptococcus gordonii that incorporates the nutrient flux that occurs in the oral cavity was developed. This model was used to characterize the biphasic expansion of the adherent bacterial population, which corresponded with the emergence of higher-order architectures characteristic of biofilms. Biofilm formation by S. gordonii was observed to be influenced by the presence of simple sugars including sucrose, glucose, and fructose. Real-time PCR was used to quantify changes in expression of S. gordonii genes known or thought to be involved in biofilm formation. Morphological changes were accompanied by a significant shift in gene expression patterns. The majority of S. gordonii genes examined were observed to be downregulated in the biofilm phase. Genes found to be upregulated in the biofilm state were observed to encode products related to environmental sensing and signaling.

scholarly journals Identification of cis-elements regulating the expression of an Arabidopsis histone H4 gene

1996 ◽  
Vol 10 (3) ◽  
pp. 425-435 ◽  
Author(s):  
Nicole Chaubet ◽  
Martine Flenet ◽  
Bernadette Clement ◽  
Pierre Brignon ◽  
Claude Gigot
Keyword(s):  
Cis Elements ◽  
Histone H4 ◽  
Histone H4 Gene

scholarly journals Pathogenesis and characteristics of large ameloblastoma of the jaw: a report of two rare cases

2021 ◽  
Vol 49 (5) ◽  
pp. 030006052110148
Author(s):  
Xue Qiao ◽  
Xing Niu ◽  
Jiayi Liu ◽  
Lijie Chen ◽  
Yan Guo ◽  
...  
Keyword(s):  
Gene Expression ◽  
Epithelial Mesenchymal Transition ◽  
Morphological Changes ◽  
Molecular Evidence ◽  
Nucleotide Polymorphisms ◽  
Related Gene ◽  
Epithelial Tumor ◽  
Single Nucleotide ◽  
Mesenchymal Transition ◽  
Hras Gene

Ameloblastoma is a common odontogenic epithelial tumor that exhibits various biological behaviors, ranging from simple cystic expansion to aggressive solid masses characterized by local invasiveness, a high risk of recurrence, and even malignant transformation. We report on two cases of unusually large solid ameloblastomas. We detected epithelial–mesenchymal transition-related gene expression and HRAS gene single nucleotide polymorphisms, providing possible molecular evidence of mesenchymal morphological changes in ameloblastoma. The detailed analysis of the pathogenesis of these two cases of ameloblastoma may deepen our understanding of this rare disease and offer promising targets for future targeted therapy.

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