A meta-analysis of the polyunsaturated fatty acid composition of erythrocyte membranes in schizophrenia

2012 ◽  
Vol 141 (2-3) ◽  
pp. 153-161 ◽  
Author(s):  
W.J.M. van der Kemp ◽  
D.W.J. Klomp ◽  
R.S. Kahn ◽  
P.R. Luijten ◽  
H.E. Hulshoff Pol
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Polyunsaturated Fatty Acid ◽  
Meta Analysis ◽  
Erythrocyte Membranes

scholarly journals Influence of Pancreatic Status and Sex on Polyunsaturated Fatty Acid Profiles in Cystic Fibrosis

2008 ◽  
Vol 54 (2) ◽  
pp. 388-395 ◽  
Author(s):  
Thierry Charles Coste ◽  
Gladys Deumer ◽  
Gregory Reychler ◽  
Patrick Lebecque ◽  
Pierre Wallemacq ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Docosahexaenoic Acid ◽  
Acid Composition ◽  
Polyunsaturated Fatty Acid ◽  
Eicosatrienoic Acid ◽  
Erythrocyte Membranes ◽  
Healthy Controls ◽  
Mead Acid

Abstract Background: Some but not all studies have reported abnormal polyunsaturated fatty acid composition in cystic fibrosis (CF) patients. We investigated the influence of pancreatic status and sex on the fatty acid profile in plasma and erythrocyte membranes in patients with CF. Methods: After a 1-step transesterification with acetyl chloride on plasma and washed erythrocyte membranes, we quantified fatty acid methyl esters by use of GC-MS in 124 CF patients and 80 age-matched healthy controls. In the CF group, mean (SD) age was 17.5 (11.3) years, and 51.6% were male. Pancreatic insufficiency was diagnosed in 78% of the CF population. Results: A decrease in docosahexaenoic acid concentrations was observed in CF patients independently of pancreatic status. Pancreatic insufficient CF patients displayed lower concentrations of linoleic acid and arachidonic acid and higher concentrations of dihomo-γ-linolenic acid and eicosatrienoic acid (mead acid) in plasma and erythrocyte membranes compared with healthy controls and pancreatic sufficient CF patients. Male CF patients had significantly lower docosahexaenoic acid and higher eicosatrienoic acid in plasma and erythrocyte membranes compared with female CF patients. Conclusions: These results support the concept that multiple abnormalities of polyunsaturated fatty acid composition participate in the CF disease phenotype and that pancreatic status plays a major role in such abnormalities. Moreover, patient sex influences the polyunsaturated fatty acid spectrum in CF, with more marked abnormalities in males.

Fatty acid composition of phospholipids in erythrocyte membranes and risk of breast cancer

1990 ◽  
Vol 45 (5) ◽  
pp. 807-810 ◽  
Author(s):  
D. G. Zaridze ◽  
V. E. Chevchenko ◽  
A. A. Levtshuk ◽  
Y. E. Lifanova ◽  
D. M. Maximovitch
Keyword(s):  
Breast Cancer ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Erythrocyte Membranes

scholarly journals Oilseed Lipid Supplements and Fatty Acid Composition of Cow Milk: A Meta-Analysis

2008 ◽  
Vol 91 (12) ◽  
pp. 4687-4703 ◽  
Author(s):  
F. Glasser ◽  
A. Ferlay ◽  
Y. Chilliard
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Meta Analysis ◽  
Cow Milk

Fatty Acid Composition of the Erythrocyte Membranes Varies between Early-Term, Full-Term, and Late-Term Infants in Japan

2018 ◽  
Vol 73 (4) ◽  
pp. 335-343 ◽  
Author(s):  
Yohei Kitamura ◽  
Chieko Kogomori ◽  
Hirokazu  Hamano ◽  
Iwao Maekawa ◽  
Takashi Shimizu ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Full Term ◽  
Erythrocyte Membranes ◽  
Term Infants ◽  
Early Term ◽  
Gestational Period ◽  
The Third ◽  
Study Results

Background: Term infants can be categorized into 3 sub-groups: early term (37w0d to 38w6d), full term (39w0d to 40w6d), and late term (41w0d and beyond). However, the fatty acid composition among the 3 groups of term infants has not been investigated. The association between fatty acid composition and gestational period of term infants in Japan is unclear. Methods: We assessed the fatty acid composition of maternal erythrocyte membranes in the third trimester and of cord erythrocyte membranes at birth in 212 healthy term Japanese infants using data from a prospective hospital-based cohort study. Results: In maternal erythrocyte membranes, docosahexaenoic acid (DHA) levels and omega-3 index were significantly higher in the late-term group than in the early-term group. In cord erythrocyte membranes, DHA levels were not significantly different between the 3 groups; late-term infants showed significantly higher DHA/arachidonic acid (ARA) and lower 20: 3n-6 and ARA levels compared to early-term infants. Gestational period positively correlated with the DHA status in maternal and cord erythrocyte membranes. Conclusions: Fatty acid composition in maternal and cord erythrocyte membranes varies between early-, full-, and late-term infants, and the greater gestational period may contribute to the relatively high n-3 polyunsaturated fatty acids status in term infants. Furthermore, maternal DHA status in the third semester directly correlates with gestational period in pregnant Japanese women.

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