Corrigendum to “A randomized controlled trial of the effect of sublingual orally disintegrating olanzapine versus oral olanzapine on body mass index: The PLATYPUS Study” Schizophr. Res. 113 (2009) 41-48

2011 ◽  
Vol 133 (1-3) ◽  
pp. 266
Author(s):  
J. Karagianis ◽  
L. Grossman ◽  
J. Landry ◽  
V.A. Reed ◽  
L. de Haan ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Randomized Controlled Trial ◽  
Body Mass ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Oral Olanzapine

scholarly journals Revisiting the Heterogeneous IFN-γ Response of Bacille of Calmette-Guérin (BCG)-Revaccinated Healthy Volunteers in a Randomized Controlled Trial: Effect of the Body Mass Index and of the IFNG+874 A/T Polymorphism

PLoS ONE ◽  
2016 ◽  
Vol 11 (7) ◽  
pp. e0160149 ◽  
Author(s):  
Elisabete L. Conceição ◽  
Francisco S. Nascimento-Sampaio ◽  
Paulo A. Schwingel ◽  
Evelin S. Oliveira ◽  
Michael S. Rocha ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Randomized Controlled Trial ◽  
Healthy Volunteers ◽  
Body Mass ◽  
Controlled Trial ◽  
The Body ◽  
Trial Effect ◽  
Randomized Controlled ◽  
Ifn Γ

scholarly journals Different Limb Lengths in Gastric Bypass Surgery: Study Protocol for A Swiss Multicenter Randomized Controlled Trial (SLIM)

2020 ◽  
Author(s):  
Marko Kraljević ◽  
Romano Schneider ◽  
Bettina Wölnerhanssen ◽  
Marco Bueter ◽  
Tarik Delko ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Body Mass Index ◽  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Gastric Bypass ◽  
Body Mass ◽  
Controlled Trial ◽  
Morbidly Obese ◽  
Randomized Controlled ◽  
Multicenter Randomized Controlled Trial

Abstract Background Obesity and type 2 diabetes mellitus (T2DM) are reaching epidemic proportions. In morbidly obese patients, bariatric operations lead to sustained weight loss and relief of comorbidities in the majority of patients. Laparoscopic Roux-Y-gastric bypass (RYGB) is one of the most frequently performed operations, but it is still unknown why some patients respond better than others. Therefore, a number of variations of this operation have been introduced. Recent evidence suggests that a longer bypassed biliopancreatic limb (BPL) has the potential to be more effective compared to the standard RYGB with a shorter BPL length. This article describes the design and protocol of a randomized controlled trial comparing the outcome of a RYGB operation with a long versus short BPL.Methods/Design The trial is designed as a multicenter, randomized, patient and observer blinded trial. The relevant ethics committee has approved the trial protocol. To demonstrate that long BPL RYGB is superior compared to short BPL RYGB in terms of weight loss and resolution of T2DM the study is conducted as a superiority trial. Postoperative percent excess body mass index loss (%EBMIL) is the primary endpoint, whereas morbidity, mortality, remission of obesity related comorbidities and quality of life are secondary endpoints. Eight hundred patients, between 18 and 65 years and with a body mass index (BMI) from 35 to 60 kg/m2 who meet the regulatory rules for bariatric surgery in Switzerland will be randomized. The endpoints and baseline measurements will be assessed pre-, intra- and postoperatively.Discussion With its high number of patients and a 5-year follow-up this study will answer questions about effectiveness and safety of long BPL RYGB and provide level I evidence for improvement of the standard RYGB. These findings might therefore potentially influence global bariatric surgery guidelines.Trial registration This trial was registered on ClinicalTrials.gov under the identifier NCT04219787, on January 7th, 2020.

Sign in / Sign up

Export Citation Format

Share Document