Self-face recognition and theory of mind in patients with schizophrenia and first-degree relatives

2006 ◽  
Vol 88 (1-3) ◽  
pp. 151-160 ◽  
Author(s):  
Farzin Irani ◽  
Steven M. Platek ◽  
Ivan S. Panyavin ◽  
Monica E. Calkins ◽  
Christian Kohler ◽  
...  
Keyword(s):  
Face Recognition ◽  
Theory Of Mind ◽  
First Degree Relatives

Theory-of-mind understanding and theory-of-mind use in unaffected first-degree relatives of schizophrenia and bipolar disorder

2015 ◽  
Vol 230 (2) ◽  
pp. 735-737 ◽  
Author(s):  
Yong-guang Wang ◽  
David L. Roberts ◽  
Yan Liang ◽  
Jian-fei Shi ◽  
Kai Wang
Keyword(s):  
Bipolar Disorder ◽  
Theory Of Mind ◽  
First Degree Relatives

No evidence for impaired 'theory of mind' in unaffected first-degree relatives of schizophrenia patients

2004 ◽  
Vol 110 (2) ◽  
pp. 146-149 ◽  
Author(s):  
O. Kelemen ◽  
S. Keri ◽  
A. Must ◽  
G. Benedek ◽  
Z. Janka
Keyword(s):  
Theory Of Mind ◽  
First Degree Relatives

scholarly journals Social cognition in first-degree relatives of bipolar disorder: Theory of Mind and nonverbal sensitivity

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0246908
Author(s):  
Usue Espinós ◽  
Enrique G. Fernández-Abascal ◽  
Mercedes Ovejero ◽  
Guillermo Lahera
Keyword(s):  
Bipolar Disorder ◽  
Social Cognition ◽  
Theory Of Mind ◽  
Social Cognitive ◽  
Control Group ◽  
Type I ◽  
Nonverbal Sensitivity ◽  
First Degree Relatives ◽  
Significant Impairment ◽  
Bipolar Patients

Social cognition might be impaired in first degree relatives (FDR) of BD but existing research shows controversial results about social cognitive impairments in this population. The aim of this study was to assess Theory of Mind (ToM) and nonverbal sensitivity in FDR of BD and compare the results with those of two groups of persons with remitted bipolar disorder (BD), type I and II, and a control group. Social cognitive ability was examined in first degree relatives of BD, with a biological parent, offspring or sibling diagnosed with the disorder. For this study, 37 FDRs of bipolar patients, 37 BD I, 40 BD II and 40 control participants were recruited. Social cognition was explored by means of the Reading the Mind in the Eyes Test and the MiniPONS. Results showed a significant impairment in FDR of BD in the ToM task, but not in nonverbal sensitivity. Performance of FDRs in social cognition is better than that of BDs (either type I or type II) but worse when compared with that of healthy individuals without a family history of psychiatric disorders. Nevertheless, no differences were found between BD I and BD II groups. Males and older participants showed a worse performance in all groups. Group family therapy with FDRs of BD might include training in the recognition of nonverbal cues, which might increase the understanding of their familiars with BD, in order to modify communication abilities.

scholarly journals Impaired theory of mind in unaffected first‐degree relatives of patients with anorexia nervosa

2019 ◽  
Vol 27 (6) ◽  
pp. 692-699 ◽  
Author(s):  
Fernanda Tapajóz ◽  
Sebastian Soneira ◽  
Natalia Catoira ◽  
Alfredo Aulicino ◽  
Ricardo F. Allegri
Keyword(s):  
Anorexia Nervosa ◽  
Theory Of Mind ◽  
First Degree Relatives

scholarly journals The role of schizotypal traits and the OXTR gene in theory of mind in schizophrenia: A family-based study

2020 ◽  
Vol 63 (1) ◽  
Author(s):  
M. Giralt-López ◽  
S. Miret ◽  
J. Soler ◽  
S. Campanera ◽  
M. Parellada ◽  
...  
Keyword(s):  
Theory Of Mind ◽  
Receptor Gene ◽  
Schizophrenia Spectrum Disorders ◽  
Healthy Individuals ◽  
Oxytocin Receptor Gene ◽  
Genetic Liability ◽  
Schizotypal Personality ◽  
First Degree Relatives ◽  
Modifying Effect

Abstract Background. There is consistent evidence that theory of mind (ToM) is impaired in schizophrenia (SZ); however, it remains unclear whether such deficits are trait- or state-dependent. We evaluated ToM in patients with schizophrenia spectrum disorders (SSDs), their healthy first-degree relatives, and controls to test its suitability as an endophenotypic marker. We also studied the modifying effect of markers of clinical and genetic liability to SZ (schizotypy and genetic variability in the oxytocin receptor gene: OXTR) on ToM in healthy individuals. Methods. The sample included 38 stable SSD patients, 80 unaffected first-degree relatives, and 81 controls. ToM was assessed using the Hinting Task (HT) and schizotypy via the Schizotypal Personality Questionnaire-Brief (SPQ-B), which generates interpersonal (SPQ-IP), cognitive-perceptual (SPQ-CP), and disorganization (SPQ-D) scores. The polymorphism rs53576 of OXTR was genotyped. Results. Patients presented poorer HT performance than relatives and controls (p = 0.003 and p < 0.001). High SPQ-IP and SPQ-CP scores correlated with poorer ToM performance in relatives (p = 0.010 and p = 0.030), but not in controls. OXTR was not associated with HT scores, but it showed a modifying effect within controls; high SPQ-CP was related to HT poorer performance conditional to GG genotype (p = 0.007). Conclusions. ToM deficits were present in patients but not in unaffected relatives or controls. However, our data indicate the usefulness of clinical and genetic liability markers to characterize differences in ToM abilities within healthy individuals. Then, the observed link between ToM and SZ liability suggests the putative role of ToM as an endophenotypic marker. Nevertheless, new analyses in larger samples are needed.

scholarly journals Theory of Mind in Borderline Personality Disorder: A Possible Endophenotypic Factor?

2021 ◽  
Vol 18 (6) ◽  
pp. 3193
Author(s):  
Esther Ortega-Díaz ◽  
Jonatan García-Campos ◽  
Alejandro Moya-Martínez ◽  
Clara Ramírez-Cremades ◽  
José M. Rico-Gomis ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Theory Of Mind ◽  
Case Control Study ◽  
Borderline Personality ◽  
Correct Interpretation ◽  
First Degree Relatives ◽  
Familial Vulnerability ◽  
And Control ◽  
Control Study

The purpose of this study is to examine whether theory of mind (ToM) is an endophenotypic marker of borderline personality disorder (BPD), thus constituting an etiopathogenic factor of the disease. This would suggest familial vulnerability to BPD. This was a case-control study involving 146 individuals with 57 BPD patients, 32 first-degree relatives, and 57 controls (median age of BPD and control = 33.4 years; relatives = 52.9 years; BPD females and controls = 91.2%; female relatives = 62.5%). All the participants completed the Spanish version of the Movie for the Assessment of Social Cognition test to evaluate the ToM subclassification: interpretation of emotions, thoughts and intentions. BPD patients and their healthy first-degree relatives exhibited significant deficits in the correct interpretation of emotions and intentions compared to healthy controls. Both patients with BPD and their healthy first-degree relatives exhibited significant deficits in ToM, which suggests that it may be an etiopathogenic factor of BPD, and ToM (interpretation of emotions, thoughts and intentions) is a possible endophenotypic marker of BPD, suggesting a genetic predisposition to the disorder. Therefore, ToM could be considered as an indicator for the early detection of the disorder of and intervention for BPD.

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