Interaction between fluorescein isothiocyanate and carbon dots: Inner filter effect and fluorescence resonance energy transfer

Author(s):  
Huabing Liu ◽  
Chaoyong Xu ◽  
Yanli Bai ◽  
Lin Liu ◽  
Dongmei Liao ◽  
...  
Nanomedicine ◽  
2021 ◽  
Author(s):  
Abolghasem Abbasi Kajani ◽  
Masoud Ayatollahi Mehrgardi

Aim: To develop a novel theranostic nanoplatform for simultaneous fluorescent monitoring and stimuli-triggered drug delivery. Materials & methods: Different microscopic and spectroscopic techniques were used for the characterization of nanocarriers. MCF-7 and human umbilical vein endothelial cell lines were cultured and treated with different doses of doxorubicin-loaded nanocarriers. The cell viability and drug release were studied using MTT assay and fluorescence microscopy. Results: Biocompatible and mono-disperse nanocarriers represent hollow and mesoporous structures with the calculated surface area of 552.83 m2.g-1, high magnetic activity (12.6 emu.g-1), appropriate colloidal stability and high drug loading capacity (up to 61%). Conclusion: Taxane-based carbon dots act as the pH-responsive gatekeepers for the controlled release of doxorubicin into cancer cells and provide a fluorescence resonance energy transfer system for real-time monitoring of drug delivery.


RSC Advances ◽  
2015 ◽  
Vol 5 (79) ◽  
pp. 64790-64796 ◽  
Author(s):  
Ying Shi ◽  
Chunyan Li ◽  
Shaopu Liu ◽  
Zhongfang Liu ◽  
Jinghui Zhu ◽  
...  

A carbon dot-based fluorescence probe was designed for detecting curcumin via fluorescence resonance energy transfer.


2015 ◽  
Vol 7 (12) ◽  
pp. 5067-5073 ◽  
Author(s):  
M. Reza Hormozi-Nezhad ◽  
M. Taghipour

In this study, a novel approach for sensitive and extremely selective detection of copper ions has been developed based on fluorescence resonance energy transfer (FRET) between AuNPs as an acceptor and fluorescein isothiocyanate (FITC) as a donor.


2018 ◽  
Vol 6 (15) ◽  
pp. 2315-2322 ◽  
Author(s):  
Di Yang ◽  
Shanyue Guan ◽  
Yuefang Niu ◽  
Zheng Xie ◽  
Shuyun Zhou ◽  
...  

Hypoxia responsive upconversion nano-aggregates are synthesized which can be excited by NIR light to give oxygen dependent phosphorescence emission via the FRET process.


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