Simultaneous first order derivative spectrophotometric determination of vanadium and zirconium in alloy steels and minerals

2012 ◽  
Vol 95 ◽  
pp. 46-52 ◽  
Author(s):  
Anitha Varghese ◽  
Louis George
Keyword(s):  
Spectrophotometric Determination ◽  
Order Derivative ◽  
First Order ◽  
Alloy Steels

scholarly journals Derivative spectrophotometric determination of acetamiprid in the presence of 6-chloronicotinic acid

2012 ◽  
Vol 77 (7) ◽  
pp. 911-917 ◽  
Author(s):  
Valéria Guzsvány ◽  
Sanja Lazic ◽  
Natasa Vidakovic ◽  
Zsigmond Papp
Keyword(s):  
Simultaneous Determination ◽  
Spectrophotometric Determination ◽  
Spectrophotometric Method ◽  
Detection Limits ◽  
Model Systems ◽  
Order Derivative ◽  
Zero Crossing ◽  
First Order ◽  
Relative Standard

A simple first-order derivative spectrophotometric method was developed for the simultaneous determination of acetamiprid and 6-chloronicotinic acid (6-CNA) at pH 7.0. By using the zero-crossing approach, acetamiprid was determined at 269.0 nm and 6-CNA at 216.0 nm with the detection limits of 7.19x10-7 and 8.25x10-7 mol dm-3, respectively and relative standard deviations not exceeding 1.2% in the case of model systems.

scholarly journals UV Spectrophotometric Simultaneous Determination of Paracetamol and Ibuprofen in Combined Tablets by Derivative and Wavelet Transforms

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Vu Dang Hoang ◽  
Dong Thi Ha Ly ◽  
Nguyen Huu Tho ◽  
Hue Minh Thi Nguyen
Keyword(s):  
Simultaneous Determination ◽  
Wavelet Transforms ◽  
Hybrid Approach ◽  
Uv Spectra ◽  
Order Derivative ◽  
First Order ◽  
Spectrophotometric Methods ◽  
Combined Use ◽  
Linear Concentration

The application of first-order derivative and wavelet transforms to UV spectra and ratio spectra was proposed for the simultaneous determination of ibuprofen and paracetamol in their combined tablets. A new hybrid approach on the combined use of first-order derivative and wavelet transforms to spectra was also discussed. In this application, DWT (sym6 and haar), CWT (mexh), and FWT were optimized to give the highest spectral recoveries. Calibration graphs in the linear concentration ranges of ibuprofen (12–32 mg/L) and paracetamol (20–40 mg/L) were obtained by measuring the amplitudes of the transformed signals. Our proposed spectrophotometric methods were statistically compared to HPLC in terms of precision and accuracy.

Fourth Order Derivative Spectrophotometric Determination of Lead with 1,10-Phenanthroline and Rose Bengal

1993 ◽  
Vol 26 (3) ◽  
pp. 523-539 ◽  
Author(s):  
D. Sreevalsan Nair ◽  
T. Prasada Rao ◽  
C. S. P. Iyer ◽  
A. D. Damodaran
Keyword(s):  
Spectrophotometric Determination ◽  
Fourth Order ◽  
Rose Bengal ◽  
Order Derivative

scholarly journals Spectrophotometric Determination of Olmutinib in Bulk by Area under Curve and First Order Derivative Methods and its Validation as per ICH guidelines

2019 ◽  
Vol 9 (4-A) ◽  
pp. 349-354
Author(s):  
BALU KHANDARE ◽  
Atish C. Musle ◽  
Sanket S. Arole ◽  
Pravin V. Popalghat
Keyword(s):  
Area Under Curve ◽  
Limit Of Detection ◽  
Order Derivative ◽  
Spectrometric Method ◽  
First Order ◽  
Accuracy And Precision ◽  
Ich Guidelines ◽  
Validation Parameters ◽  
Limit Of Quantitation

Abstract: A simple, precise and economical UV-spectrophotometric method has been developed for the estimation of Olmutinib from bulk. Two methods were developed First method (A) applied was area under curve (AUC) in which the area was integrated in wavelength from 262-272nm. Second method (B) was first order derivative spectrometric method. In this method absorbance at λmin=256.57nm, λmax=282.83nm and zero cross=267.68nm was measured. Calibration curves were plotted for the method by using instrumental response at selected wavelength and concentration of analyte in the solution. In both the methods, linearity was observed in the concentration range of 2-12µg/ml at the λmax=267.68nm. Accuracy and precision studies were carried out and results were satisfactorily obtained. The drug at each of the 80 %, 100 % and 120 % levels showed good recoveries that is in the range of 98.00 to 99.00% for both methods, hence it could be said that the method was accurate. Limit of detection (LOD) and limit of quantitation (LOQ) were determined for the method. The method was validated as per International Conference on Harmonization. All validation parameters were within the acceptable limit. The developed method was successfully applied to estimate the amount of Olmutinib in pharmaceutical formulation.

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