The effect of titanium dioxide on the biochemical constituents of the brain of Zebrafish (Danio rerio): An FT-IR study

2011 ◽  
Vol 79 (1) ◽  
pp. 206-212 ◽  
Author(s):  
PL.RM. Palaniappan ◽  
K.S. Pramod
Keyword(s):  
Titanium Dioxide ◽  
Danio Rerio ◽  
Biochemical Constituents ◽  
Ft Ir ◽  
Ir Study ◽  
The Brain

scholarly journals Recent results on biomedical problems: A Fourier transform infrared (FT‒IR) study

2002 ◽  
Vol 16 (3-4) ◽  
pp. 245-250
Author(s):  
V. Crupi ◽  
S. Galli ◽  
D. Majolino ◽  
P. Migliardo ◽  
S. Pergolizzi ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Fourier Transform Infrared ◽  
Normal Brain ◽  
Spectral Features ◽  
Spectral Contribution ◽  
Vibrational Bands ◽  
Ft Ir ◽  
Ir Study ◽  
Rat Tissue ◽  
The Brain

In the present work, we report on a vibrational study performed on rat encephalon samples and on human tissue affected by cancer, using Fourier Transform Infrared absorbance spectroscopy. As the brain rat tissue is concerned, the FT-IR measurements, performed in the CH–OH vibrational stretching region (2400–3800 cm−1), permitted us to reveal the presence of a very diffuse commercial benzodiazepine: VALIUM®. The comparison between the spectral features of normal brain and the ones of samples with administrated substance has unambiguously showed that the CH stretching region seems not to be affected by any change for the pharmacological treatment, instead the OH band is strongly modified probably due to the presence of a new spectral contribution characteristic of diazepam molecule. In the case of skin tissue the investigation was addressed to characterize the presence of two different pathologies, namely epithelioma and basalioma, and to show clear different spectral features passing from the normal tissue to the malignant one in particular in the region (1500–2000 cm−1) which is typical of the lipids vibrational bands.

The FT-IR study of the brain tissue of Labeo rohita due to arsenic intoxication

2009 ◽  
Vol 91 (1) ◽  
pp. 118-124 ◽  
Author(s):  
PL.RM. Palaniappan ◽  
V. Vijayasundaram
Keyword(s):  
Brain Tissue ◽  
Labeo Rohita ◽  
Ft Ir ◽  
Ir Study ◽  
The Brain

Synthesis of Functionalized Magnetite Titanium Dioxide Nanocomposite for Removal of Acid Fuchsine Dye

2018 ◽  
Vol 21 (8) ◽  
pp. 583-593 ◽  
Author(s):  
Sara Rahnama ◽  
Shahab Shariati ◽  
Faten Divsar
Keyword(s):  
Titanium Dioxide ◽  
Removal Efficiency ◽  
Magnetic Core ◽  
Fractional Factorial ◽  
Order Kinetic ◽  
Sorption Data ◽  
Salt Addition ◽  
Order Kinetic Model ◽  
Pseudo Second Order ◽  
Ft Ir

Objective: In this research, a novel magnetite titanium dioxide nanocomposite functionalized by amine groups (Fe3O4@SiO2@TiO2-NH2) was synthesized and its ability for efficient removal of Acid Fuchsine as an anionic dye from aqueous solutions was investigated. Method: The core-shell structure of Fe3O4@SiO2@TiO2 was prepared using Fe3O4 as magnetic core, tetra ethyl orthosilicate as silica and tetra butyl titanate as titanium source for shell. The synthesized nanocomposites (particle size lower than 44 nm) were characterized by FT-IR, XRD, DRS, SEM and TGA instruments. The various experimental parameters affecting dye removal efficiency were investigated and optimized using Taguchi fractional factorial design. Results: The synthesized adsorbent showed the highest removal efficiency of Acid Fuchsine (99 %) at pH= 3.5, without salt addition and during stirring at contact times less than 10 minutes. The study of kinetic models at two concentration levels showed the fast dye sorption on the surface of proposed nanocomposites with pseudo second order kinetic model (R2=1). Also, the fitting of Acid Fuchsine sorption data to Freundlich, Langmuir and Temkin isotherms suggested that Freundlich model gave a better fitting than other models (R2=0.9936, n=2). Conclusion: Good chemical stability, excellent magnetic properties, very fast adsorption kinetics and high removal efficiency make the synthesized nanocomposite as a proper recoverable sorbent for removal of Acid Fuchsine dye from wastewaters.

scholarly journals Unraveling the neurotoxicity of titanium dioxide nanoparticles: focusing on molecular mechanisms

2016 ◽  
Vol 7 ◽  
pp. 645-654 ◽  
Author(s):  
Bin Song ◽  
Yanli Zhang ◽  
Jia Liu ◽  
Xiaoli Feng ◽  
Ting Zhou ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Titanium Dioxide ◽  
Molecular Mechanisms ◽  
Titanium Dioxide Nanoparticles ◽  
Brain Dysfunction ◽  
In Vivo Studies ◽  
Cell Components ◽  
New Perspective ◽  
The Brain

Titanium dioxide nanoparticles (TiO2 NPs) possess unique characteristics and are widely used in many fields. Numerous in vivo studies, exposing experimental animals to these NPs through systematic administration, have suggested that TiO2 NPs can accumulate in the brain and induce brain dysfunction. Nevertheless, the exact mechanisms underlying the neurotoxicity of TiO2 NPs remain unclear. However, we have concluded from previous studies that these mechanisms mainly consist of oxidative stress (OS), apoptosis, inflammatory response, genotoxicity, and direct impairment of cell components. Meanwhile, other factors such as disturbed distributions of trace elements, disrupted signaling pathways, dysregulated neurotransmitters and synaptic plasticity have also been shown to contribute to neurotoxicity of TiO2 NPs. Recently, studies on autophagy and DNA methylation have shed some light on possible mechanisms of nanotoxicity. Therefore, we offer a new perspective that autophagy and DNA methylation could contribute to neurotoxicity of TiO2 NPs. Undoubtedly, more studies are needed to test this idea in the future. In short, to fully understand the health threats posed by TiO2 NPs and to improve the bio-safety of TiO2 NPs-based products, the neurotoxicity of TiO2 NPs must be investigated comprehensively through studying every possible molecular mechanism.

An FT-IR Study on Packing Defects in Mixed β-Aggregates of Poly(l-glutamic acid) and Poly(d-glutamic acid): A High-Pressure Rescue from a Kinetic Trap

2012 ◽  
Vol 116 (17) ◽  
pp. 5172-5178 ◽  
Author(s):  
Yudai Yamaoki ◽  
Hiroshi Imamura ◽  
Aleksandra Fulara ◽  
Sławomir Wójcik ◽  
Łukasz Bożycki ◽  
...  
Keyword(s):  
High Pressure ◽  
Glutamic Acid ◽  
Kinetic Trap ◽  
Packing Defects ◽  
Ft Ir ◽  
Ir Study

AN ENHANCEMENT OF SOLUBILITY OF PIOGLITAZONE HYDROCHLORIDE USING LIQUISOLID TECHNIQUE

INDIAN DRUGS ◽  
2013 ◽  
Vol 50 (06) ◽  
pp. 36-39
Author(s):  
S Deshmane ◽  
◽  
K Gandhi ◽  
S. Nagpure ◽  
A. Sawant ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Drug Release ◽  
Dissolution Rate ◽  
In Vivo Study ◽  
Dimethyl Acetamide ◽  
Volatile Liquid ◽  
Ft Ir ◽  
Ir Study

The new mathematical model was developed by studying angle of slide using N, N-dimethyl acetamide, non-volatile liquid vehicle and prepared liquisolid tablets, in which the different concentrations of non-volatile liquid adsorbed over carrier and coating material separately. Both DSC and FT-IR study showed better compatibility and stability. The optimized formulation showed higher drug release during in-vitro and in-vivo study against conventional and marketed preparation. The present work concludes that N, N-dimethyl acetamide enhanced the solubility of pioglitazone HCl with higher dissolution rate through liquisolid technique.

FT-IR study on solvent effects in building blocks of bioactive compounds. V

2006 ◽  
Vol 790 (1-3) ◽  
pp. 89-93
Author(s):  
C. Conti ◽  
R. Galeazzi ◽  
E. Giorgini ◽  
G. Tosi
Keyword(s):  
Bioactive Compounds ◽  
Solvent Effects ◽  
Building Blocks ◽  
Ft Ir ◽  
Ir Study
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