Determination of normal values for an isocapnic hyperpnea endurance test in healthy individuals

2016 ◽  
Vol 230 ◽  
pp. 5-10 ◽  
Author(s):  
Marjolaine Vincent ◽  
Isabelle Court-Fortune ◽  
Clément Brun ◽  
Jean-Philippe Camdessanché ◽  
Samuel Vergès ◽  
...  
Keyword(s):  
Normal Values ◽  
Healthy Individuals ◽  
Endurance Test ◽  
Isocapnic Hyperpnea

scholarly journals Study of hemolytic activity and subfactors of complement in smokers intoxication

2019 ◽  
Author(s):  
Rojan Ghanim Al Allaf
Keyword(s):  
Hemolytic Activity ◽  
Normal Values ◽  
Control Group ◽  
Healthy Individuals ◽  
Complement Components ◽  
Complement Activity ◽  
Normal People ◽  
Hemolytic Complement Activity ◽  
Heavy Smokers

Abstract Heavy Smokers appeared to be less resistant to infection, such as bacteria, viruses, and parasites. Many studies have examined the complement components concentrations than compared with normal people and ignored the functional sequencing of complement components, our study included the determination of complement activity by using Sheep red blood cells (SRBCs) as antigen and extracting the hemolytic activity (50%) of complement compounds, and because of difficulty of this method we using statistical analysis program (SPSS 23) and derived the inverse equation which gives the decomposition percentage (1-100%) of complement components by using five serum dilutions only. The total hemolytic complement activity (CH50) and its C3 and C4 fractions were determined in 30 heavy smokers. The results were compared with a control group that contained 30 persons matched in age and sex. Generally, both C3 and C4 concentrations were increased in smoker's individual in compared with the control group. However, when the independent t-test has applied the differences in the C3 and C4 levels in the control group (healthy individuals) and in the smoker group were found to be statistically insignificant but the inverse equation showed a 7% reduction in CH50 in smokers compared with the control group, where 18% reduction was observed. Our current study suggests that the complement components of the heavy smokers suffer from a significant dysfunction in the function, although the concentration of the basic components in the serum is parallel with normal values.

Determination of normal values for an isocapnic hyperventilation endurance test

2015 ◽  
Author(s):  
Marjolaine Vincent ◽  
Isabelle Court Fortune ◽  
Jean Philippe Camdessanche ◽  
Frédéric Costes
Keyword(s):  
Normal Values ◽  
Endurance Test

The muscle fatigue of external anal sphincter in patients with anal incontinence

2017 ◽  
pp. 69-75
Author(s):  
О.Ю. Фоменко ◽  
Ю.А. Шелыгин ◽  
Г.В. Порядин ◽  
А.Ю. Титов ◽  
Е.А. Берсенева ◽  
...  
Keyword(s):  
Muscle Fatigue ◽  
Anal Sphincter ◽  
Anal Incontinence ◽  
Normal Values ◽  
External Sphincter ◽  
Colon Polyps ◽  
Endurance Test ◽  
Water Sensor ◽  
Post Traumatic

Цель - изучение зависимости утомляемости наружного сфинктера от наличия анальной инконтиненции и степени выраженности. Методы. Для выяснения зависимости утомляемости от наличия анальной инконтиненции обследовано 203 пациента с жалобами на недержание различных компонентов кишечного содержимого: 90 мужчин (44,3%), средний возраст 44,8 ± 14,7 года и 113 женщин (55,7%), средний возраст 46,4 ± 15,2 года. Для определения нормативных величин отобраны 53 пациента с полипами ободочной кишки, без клинико-инструментальных признаков анальной инконтиненции. В состав группы вошли 23 женщины (43,4%), средний возраст 51,4 ± 11,1 года и 30 мужчин (56,6%), средний возраст 65,1 ± 15,9 года. Использован разработанный в ФГБУ ГНЦК им. А.Н. Рыжих Минздрава России метод комплексной сфинктерометрии неперфузионным датчиком водного наполнения на приборе WPM Solar GI. Результаты и обсуждение. Получены нормативные показатели теста на выносливость наружного сфинктера. Не выявлено корреляции между степенью недостаточности анального сфинктера (по показателям давления в анальном канале) и одним из параметров утомляемости (временем падения давления на 50%), вероятнее всего из-за посттравматического характера недостаточности анального сфинктера. Предполагается продолжение работы по изучению утомляемости при различном генезе анальной инконтинеции. The article presents materials on the muscle fatigue of the external sphincter in the norm and in patients with anal sphincter failure. The purpose. To determine the dependence of external sphincter fatigue on the presence of anal incontinence and its degree. Methods. 203 patients with complaints of incontinence of various components of intestinal contents were examined (90 male (44.3%), mean age is 44.8 ± 14.7 years, 113 female (55.7%) mean age is 46.4 ± 15.2 years) to determine the dependence of fatigue on the presence of anal incontinence. 53 patients with colon polyps without clinical and instrumental signs of anal incontinence were selected for the determination of normal values. 23 female (43.4%), mean age is 51.4 ± 11.1 years; 30 male (56.6%), mean age is 65.1 ± 15.9 years. For the study, we used the method of complex sphincterometry developed in State Scientific Centre of Coloproctology on the device WPM Solar GI (MMS, The Netherlands) with a nonperfusion water sensor. Results. We have received normal values for external sphincter endurance test. At the same time, there was no correlation between the degree of anal sphincter failure (in terms of pressure in the anal canal) and one of the fatigue parameters (the time of the pressure drop by 50%), most likely because of the post-traumatic nature of anal sphincter failure. We plan to continue studying fatigue with a different genesis of anal incontinence. Conclusion. We plan to continue studying fatigue with a different genesis of anal incontinence.

scholarly journals Study of hemolytic activity and subfactors of complement in smokers intoxication

2019 ◽  
Author(s):  
Rojan Ghanim Al Allaf
Keyword(s):  
Hemolytic Activity ◽  
Normal Values ◽  
Control Group ◽  
Healthy Individuals ◽  
Complement Components ◽  
Complement Activity ◽  
Normal People ◽  
Hemolytic Complement Activity ◽  
Heavy Smokers

Abstract Background: Heavy Smokers appeared to be less resistant to infection, such as bacteria, viruses, and parasites. Many studies have examined the complement components concentrations than compared with normal people and ignored the functional sequencing of complement components. Methods: our study included the determination of complement activity by using Sheep red blood cells (SRBCs) as antigen and extracting the hemolytic activity (50%) of complement compounds, and because of difficulty of this method we using statistical analysis program (SPSS 23) and derived the inverse equation which gives the decomposition percentage (1-100%) of complement components by using five serum dilutions only, The total hemolytic complement activity (CH50) and its C3 and C4 fractions were determined in 30 heavy smokers. Results: The results were compared with a control group that contained 30 persons matched in age and sex. Generally, both C3 and C4 concentrations were increased in smoker's individual in compared with the control group. However, when the independent t-test has applied the differences in the C3 and C4 levels in the control group (healthy individuals) and in the smoker group were found to be statistically insignificant but the inverse equation showed a 7% reduction in CH50 in smokers compared with the control group, where 18% reduction was observed. Conclusions: Our current study suggests that the complement components of the heavy smokers suffer from a significant dysfunction in the function, although the concentration of the basic components in the serum is parallel with normal values.

Quantification of myocardial function using MRI feature tracking in children - Determination of normal values

2014 ◽  
Vol 62 (S 02) ◽  
Author(s):  
A. Helling ◽  
S. Buss ◽  
A. Foell ◽  
D. Robbers-Visser ◽  
W.A. Helbing ◽  
...  
Keyword(s):  
Feature Tracking ◽  
Myocardial Function ◽  
Normal Values

Comparison of the Aditus ad Antrum Diameter on CT between Patients with Chronic Otitis Media and Healthy Individuals

2019 ◽  
Vol 15 (10) ◽  
pp. 990-993 ◽  
Author(s):  
Elif Gündoğdu ◽  
Uğur Toprak
Keyword(s):  
Computed Tomography ◽  
Otitis Media ◽  
Middle Ear ◽  
Healthy Subjects ◽  
Normal Values ◽  
Chronic Otitis Media ◽  
Healthy Individuals ◽  
Inner Diameter ◽  
Male Patients ◽  
The Right

Background: The middle ear cavity is ventilated through the aditus ad antrum. Aditus blockage contributes to the pathology of otitis media. Objective: To determine the normal values of the aditus ad antrum diameter on computed tomography and to investigate its relationship with chronic otitis media and related pathologies (tympanosclerosis and myringosclerosis). Methods: The temporal CT images of 162 individuals were evaluated retrospectively. In the axial sections, the inner diameter of the aditus was measured at the narrowest point at the cortex. The differences in diameter were compared between diseased and healthy ears. Results: In healthy individuals, the diameter was narrower in women. There was no difference between the right and left ears in healthy subjects. No correlation was found between age and diameter. In male patients with myringosclerosis, the diameter was slightly narrower on both sides but more marked on the left. In female patients with myringosclerosis, the diameter in both ears was slightly narrower. In cases of otitis media and tympanosclerosis, the diameter was less than that of healthy individuals, despite the lack of statistically significant result in all cases. Conclusion: The aditus ad antrum was narrower in diseased ears, indicating that a blocked aditus may contribute to the development of otitis media, as well as mucosal diseases.

scholarly journals Alanine Aminopeptidase, γ-Glutamyl Transferase and β2-microglobulin as Diagnostic Markers in Patients with Rheumatoid Arthritis

2008 ◽  
Vol 27 (1) ◽  
pp. 59-63
Author(s):  
Dejan Spasovski ◽  
Todor Gruev ◽  
Nada Marina ◽  
Jordan Calovski ◽  
Ljubinka Rajčevska ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Diagnostic Markers ◽  
Border Region ◽  
Healthy Individuals ◽  
Kinetic Assay ◽  
Renal Lesions ◽  
Alanine Aminopeptidase ◽  
Glutamyl Transferase ◽  
Higher Sensitivity

Alanine Aminopeptidase, γ-Glutamyl Transferase and β2-microglobulin as Diagnostic Markers in Patients with Rheumatoid Arthritis The purpose of this research is to evaluate the values of alanine aminopeptidase (AAP), γ-glutamyl transferase (γ-GT), and β2-Microglobulin in urine (β2-M), in untreated rheumatoid arthritis (RA) and to define the effect of untreated rheumatoid arthritis on the tubular function and brush border region. We used a kinetic assay for AAP, standard methods by the IFCC for γ-glutamyl transferase and MEIA for the determination of β2-Microglobulin in urine in 70 participants (35 untreated RA patients, 35 healthy individuals). From the total of 35 RA patients, 24 patients had AAP (sensitivity of the test 68.57%), 16 patients had γ-GT enzymuria (sensitivity of the test 45.71%), while the presence of β2-Microglobulin in urine was found in a very low percentage. Out of 18 RF negative patients, 14 patients are AAP positive, 10 patients were γ-GT positive, while the presence of β2-Microglobulin in urine was not detected. Among 17 RF positive RA patients, the presence of AAP was noticed in 10, the presence of γ-GT in 6 patients, while the presence of β2-Microglobulin in urine was not detected. AAP has higher sensitivity than γ-GT and β2-Microglobulin in the detection of asymptomatic renal lesions in untreated RA.

Colombian Study to Assess the Use of Noninvasive Determination of Endothelium-Mediated Vasodilatation (CANDEV). Normal Values and Factors Associated

Endothelium ◽  
2001 ◽  
Vol 8 (2) ◽  
pp. 157-166 ◽  
Author(s):  
Jose Luis Accin ◽  
Aristides Sotomayor ◽  
Freddy Trujillo ◽  
Juan Guillermo Barrera ◽  
Leonelo Bautista ◽  
...  
Keyword(s):  
Normal Values ◽  
Factors Associated

Is there a relation between serum methylarginine levels and infertility?

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Yasin Saygın ◽  
Abdullah Sivrikaya ◽  
Turan Akdağ ◽  
Duygu Dursunoğlu ◽  
Mehmet Kaynar ◽  
...  
Keyword(s):  
Sperm Concentration ◽  
Reproductive Period ◽  
Healthy Individuals ◽  
Adma Level ◽  
Chromatography Tandem Mass Spectrometry ◽  
Potential Biomarker ◽  
Liquid Chromatography Tandem Mass ◽  
Arginine Residues ◽  
Dimethyl Arginine

Abstract Objectives Infertility is defined as the absence of pregnancy within the reproductive period despite regular sexual intercourse. Methylarginines are formed as a result of methylation of arginine residues in proteins and formed in three forms as asymmetric dimethyl arginine (ADMA), symmetrical dimethyl arginine (SDMA) and monomethylarginine (L-NMMA). So, here, we aimed to evaluate arginine and their derivatives levels in fertile and infertile individuals. Methods Present study were consist of 30 oligozoospermia patients (proven by spermiogram analysis) and 30 healthy individuals with normozoospermia group who were applied to the urology department. With blood samples taken from individuals, serum methylarginine and its derivatives levels were analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Clinic data and demographic characteristics of individuals were also recorded at the same time. Results The serum ADMA level (0.38 ± 0.07) of the oligozoospermia group was found to be significantly higher than the normozoospermia group (0.35 ± 0.05) (p=0.046). A positive correlation were observed between ADMA and SDMA (r=0.686, p=0.000), HArg and SDMA (r=0.611, p=0.001), citrulline and L-NMMA (r=0.595, p=0.001) in patients with oligosospermia. The increase in SDMA, arginine and HArg levels and a decrease in L-NMMA and citrulline levels were not significant as statistically. Also, the ADMA level was found to be high in individuals with low sperm concentration. Conclusions Consequently, serum ADMA levels of individuals with oligozoospermia were statistically significantly higher than those with normozoospermia. As proposal, determination of ADMA levels may be a potential biomarker parameter in terms of early diagnosis of fertility and infertility.

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