scholarly journals Active acromegaly is associated with enhanced left ventricular contractility: Results from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study

2020 ◽  
Vol 39 (4) ◽  
pp. 189-196
Author(s):  
Árpád Kormányos ◽  
Péter Domsik ◽  
Anita Kalapos ◽  
Nándor Gyenes ◽  
Zsuzsanna Valkusz ◽  
...  
Keyword(s):  
Speckle Tracking ◽  
Three Dimensional ◽  
Left Ventricular ◽  
Ventricular Contractility ◽  
Left Ventricular Contractility ◽  
Active Acromegaly

scholarly journals P1795 Active acromegaly is associated with enhanced left ventricular contractility - A three-dimensional speckle-tracking echocardiographic study

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
A Kormanyos ◽  
P Domsik ◽  
A Kalapos ◽  
N Gyenes ◽  
Z Valkusz ◽  
...  
Keyword(s):  
Speckle Tracking ◽  
Interventricular Septum ◽  
Three Dimensional ◽  
Radial Strain ◽  
Human Growth ◽  
Left Ventricular ◽  
Healthy Population ◽  
Valvular Regurgitation ◽  
Ventricular Contractility ◽  
Active Acromegaly

Abstract Introduction Acromegaly is a relatively rare, chronic hormonal disease resulting in disfigurement. In 90% of the cases, acromegaly is caused by a benign pituitary monoclonal human growth hormone-secreting tumor. Hypertension and left ventricular (LV) hypertrophy are the most common cardiovascular comorbidites, but serious valvular regurgitation and heart failure could also develop at the end-stages. The aim of the present study was to determine the presence of LV deformational abnormalities using three-dimensional speckle-tracking echocardiography (3DSTE) in a group of acromegaly patients. Methods Thirty-eight acromegaly patients were involved in the present study. Thirteen patients were excluded due to inadequate image quality. The mean age of the remaining patients were 57.2 ± 13.6 years (7 males). The active acromegaly subgroup consisted of 14 patients (mean age: 58.6 ± 14.6 years, 5 males), while the inactive group contained 11 patients (mean age: 54.0 ± 12.9, 2 males). Their data was compared to an age- and gender matched control population, which comprised of 34 healthy volunteers (mean age: 52.7 ± 4.9 years, 15 males). All subjects have undergone complete two-dimensional Doppler echocardiography extended with 3DSTE. Results Significant differences in left atrial diameter and volume, LV end-diastolic diameter and volume, interventricular septum and LV posterior wall thickness could be demonstrated between the acromegaly group and healthy controls. Global and mean segmental 3DSTE-derived LV radial strain (RS)(33.2 ± 13.4% vs. 25.2 ± 10.8%, p =0.01 and 36.0 ± 12.1% vs. 28.2 ± 10.0%, p =0.009, respectively) proved to be significantly higher in acromegaly patients compared to controls. Active acromegaly patients had a significantly higher global and mean segmental RS (35.5 ± 14.4% vs. 25.2 ± 10.8%, p =0.03 and 37.9 ± 13.3% vs. 28.2 ± 10.0%, p =0.03, respectively) as compared to that of controls. Between active and inactive acromegaly groups only basal LV circumferential strain (-30.2 ± 4.8% vs. -26.7 ± 4.1%, p =0.02) was found to be significantly different. Conclusion With presented clinical, demographic, therapeutic and echocardiographic features, active acromegaly is associated with enhanced LV-RS as compared to the healthy population.

Validation of three‐dimensional echocardiographic principal strain analysis for assessing left ventricular contractility: An animal study

2019 ◽  
Vol 46 (5) ◽  
pp. 2137-2144
Author(s):  
Sahmin Lee ◽  
Seunghyun Choi ◽  
Sehwan Kim ◽  
Yeongjin Jeong ◽  
Kyusup Lee ◽  
...  
Keyword(s):  
Animal Study ◽  
Three Dimensional ◽  
Strain Analysis ◽  
Left Ventricular ◽  
Principal Strain ◽  
Ventricular Contractility ◽  
Left Ventricular Contractility

Four-Dimensional Speckle Tracking for Assessing Improvement in Left Ventricular Contractility After Coronary Angioplasty

2013 ◽  
Vol 39 (1) ◽  
pp. 102-110 ◽  
Author(s):  
Philippe Arbeille ◽  
Denis Angoulvant ◽  
Kathreen Zuj ◽  
Jeanne Patier ◽  
Bernard Desveaux ◽  
...  
Keyword(s):  
Coronary Angioplasty ◽  
Speckle Tracking ◽  
Left Ventricular ◽  
Ventricular Contractility ◽  
Left Ventricular Contractility

Early Detection of Left Ventricular Contractility Abnormalities by Two-Dimensional Speckle Tracking Strain in Chagas' Disease

2013 ◽  
Vol 31 (5) ◽  
pp. 623-630 ◽  
Author(s):  
Marcia M Barbosa ◽  
Manoel O Costa Rocha ◽  
Daniel Furtado Vidigal ◽  
Renata de Carvalho Bicalho Carneiro ◽  
Rafaela Drumond Araújo ◽  
...  
Keyword(s):  
Early Detection ◽  
Chagas Disease ◽  
Speckle Tracking ◽  
Left Ventricular ◽  
Two Dimensional ◽  
Ventricular Contractility ◽  
Left Ventricular Contractility
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