scholarly journals Prognostic value of plasma neutrophil gelatinase-associated lipocalin in patients with heart failure

2015 ◽  
Vol 34 (7-8) ◽  
pp. 473-478
Author(s):  
Humberto Villacorta ◽  
Rochele Alberto Martins Santos ◽  
Marcelle Alves Baco Marroig ◽  
Guilherme Pinella Guedes Pereira ◽  
Analucia Rampazzo Xavier ◽  
...  
2021 ◽  
Vol 26 (1) ◽  
pp. 4126
Author(s):  
N. V. Kompanets ◽  
Yu. V. Shchukin ◽  
L. V. Limareva ◽  
M. V. Komarova

Aim. To study the prognostic value of neutrophil gelatinase-associated lipocalin (NGAL or lipocalin-2) and cystatin C in patients with heart failure (HF) and myocardial infarction (MI).Material and methods. Baseline plasma concentrations of NGAL and cystatin C were measured in 119 participants (median age, 50-61 years; men, 101) with HF and primary MI (4-6 weeks old) who underwent percutaneous coronary intervention in the acute period. Adverse cardiovascular events within 1 year were considered as the endpoint.Results. Patients with elevated NGAL levels were significantly more likely to have adverse events (p<0,001). The optimal cut-off value for NGAL was 18,75 ng/ml (odds ratio, 10, 95% CI, 3,09-32,45; p=0,0001). Multivariate logistic regression showed that NGAL, N-terminal pro-brain natriuretic peptide, left ventricular aneurysm, and SYNTAX score were significant predictors of adverse events. Cystatin C did not affect prognosis in the study cohort.Conclusion. Increased NGAL levels is a predictor of unfavorable clinical outcome in patients with HF and previous MI.


2015 ◽  
Vol 34 (7-8) ◽  
pp. 473-478 ◽  
Author(s):  
Humberto Villacorta ◽  
Rochele Alberto Martins Santos ◽  
Marcelle Alves Baco Marroig ◽  
Guilherme Pinella Guedes Pereira ◽  
Analucia Rampazzo Xavier ◽  
...  

2014 ◽  
Vol 7 (1) ◽  
pp. 35-42 ◽  
Author(s):  
Vincent M. van Deursen ◽  
Kevin Damman ◽  
Adriaan A. Voors ◽  
Martje H. van der Wal ◽  
Tiny Jaarsma ◽  
...  

2013 ◽  
Vol 165 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Margarida Alvelos ◽  
Patrícia Lourenço ◽  
Carla Dias ◽  
Marta Amorim ◽  
Joana Rema ◽  
...  

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